Amy P Webster,Chrissie Thirlwell
Amy P Webster
Midgut neuroendocrine neoplasms (NENs) are one of the most common subtypes of NEN, and their incidence is rising globally. Despite being the most frequently diagnosed malignancy of the small intestine, little is known about their underlying...
Kim Henriksen,Federica Genovese,Alexander Reese-Petersen et al.
Kim Henriksen et al.
Our overview covers several key areas related to recent results obtained for collagen type VI and endotrophin (ETP). (1) An introduction to the history of ETP, including how it was identified, how it is released, and its function and potent...
What Is Carcinoid Syndrome? A Critical Appraisal of Its Proposed Mediators [0.03%]
什么是类癌综合征？对其假定介体的批判性评估
Merijn C F Mulders,Wouter W de Herder,Johannes Hofland
Merijn C F Mulders
Carcinoid syndrome (CS) is a debilitating disease that affects approximately 20% of patients with neuroendocrine neoplasms (NEN). Due to the increasing incidence and improved overall survival of patients with NEN over recent decades, patien...
Appetite- and Weight-Regulating Neuroendocrine Circuitry in Hypothalamic Obesity [0.03%]
下丘脑肥胖的相关神经内分泌调节环路研究
Hoong-Wei Gan,Manuela Cerbone,Mehul Tulsidas Dattani
Hoong-Wei Gan
Since hypothalamic obesity (HyOb) was first described over 120 years ago by Joseph Babinski and Alfred Fröhlich, advances in molecular genetic laboratory techniques have allowed us to elucidate various components of the intricate neurocirc...
Neurodevelopmental Programming of Adiposity: Contributions to Obesity Risk [0.03%]
神经发育对肥胖的影响：对肥胖风险的贡献
Alicja A Skowronski,Rudolph L Leibel,Charles A LeDuc
Alicja A Skowronski
This review analyzes the published evidence regarding maternal factors that influence the developmental programming of long-term adiposity in humans and animals via the central nervous system (CNS). We describe the physiological outcomes of...
Caterina Conte,Elisa Cipponeri,Michael Roden
Caterina Conte
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because they are not only risk factors for both acute and chronic COVID-19 manifestations, but also because COVID-19 alters energy metabolism. Such metabolic ...
Marc Gregory Yu,Daniel Gordin,Jialin Fu et al.
Marc Gregory Yu et al.
Chronic complications of diabetes are due to myriad disorders of numerous metabolic pathways that are responsible for most of the morbidity and mortality associated with the disease. Traditionally, diabetes complications are divided into th...
Marisel Rosell-Díaz,José Manuel Fernández-Real
Marisel Rosell-Díaz
The decline in cognitive function and the prevalence of neurodegenerative disorders are among the most serious threats to health in old age. The prevalence of dementia has reached 50 million people worldwide and has become a major public he...
Pei Chia Eng,Maria Phylactou,Ambreen Qayum et al.
Pei Chia Eng et al.
Obesity-related hypogonadotropic hypogonadism is a well-characterized condition in men (termed male obesity-related secondary hypogonadism; MOSH); however, an equivalent condition has not been as clearly described in women. The prevalence o...
Treating Primary Aldosteronism-Induced Hypertension: Novel Approaches and Future Outlooks [0.03%]
原发性醛固酮增多症诱导的高血压治疗：新方法及未来展望
Nathan Mullen,James Curneen,Padraig T Donlon et al.
Nathan Mullen et al.
Primary aldosteronism (PA) is the most common cause of secondary hypertension and is associated with increased morbidity and mortality when compared with blood pressure-matched cases of primary hypertension. Current limitations in patient c...