Javad Anjom-Shoae,Simon Veedfald,Arthur D Conigrave et al.
Javad Anjom-Shoae et al.
The interaction of dietary nutrients with chemoreceptors in the gastrointestinal tract after a meal stimulates the secretion of gut hormones, which trigger the key processes of digestion and absorption, and also regulate energy intake and p...
Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis [0.03%]
子痫前期的胎盘类固醇激素：内分泌发病机制的多层调控
Yun Yang,Shanshan Zhang,Xiao Fang et al.
Yun Yang et al.
The human placenta serves as the predominant endocrine organ throughout pregnancy, assuming a central role in preserving endocrine homeostasis, facilitating maternal physiological adaptation, and safeguarding fetal well-being. Preeclampsia ...
Nanna S Svensson,Tabia Volqvartz,Anna Louise Vestergaard et al.
Nanna S Svensson et al.
Vitamin D deficiency during pregnancy is associated with an increased risk of health issues in the offspring. Accordingly, recent Endocrine Society guidelines strongly support supplementation in pregnancy, also underlining that without cons...
Silvia Corvera,Akhila Rajan,Kristy L Townsend et al.
Silvia Corvera et al.
Adipose tissue has emerged as a central regulator of human physiology, with its dysfunction driving the global rise in obesity-associated diseases, such as type 2 diabetes, cardiovascular and liver diseases, and several cancers. Once though...
Immune checkpoint inhibitors in high-grade gastroenteropancreatic neuroendocrine neoplasms [0.03%]
免疫检查点抑制剂在高级别胃肠胰神经内分泌肿瘤中的应用
Nicola Fazio,Anna La Salvia
Nicola Fazio
High-grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (HG-NENs) comprise both highly proliferating well-differentiated NENs, called grade 3 NE tumors, NETs) and poorly differentiated NENs (also named NE carcinomas, NECs). The cli...
Katarzyna D Arczewska,Dorota Sys,Hilde L Nilsen et al.
Katarzyna D Arczewska et al.
The thyroid is exposed to DNA damage induced by normal physiological processes (eg, oxidative stress resulting from thyroid hormone synthesis or mitochondrial respiration) or through environmental insults (eg, environmental pollutants, ioni...
Jang Won Son,Carel W le Roux,Matthias Blüher et al.
Jang Won Son et al.
The approvals of semaglutide and tirzepatide have set new benchmarks in the treatment of type 2 diabetes and obesity. Building on their success, novel GLP-1-based therapeutics are rapidly advancing. These next-generation agents engage not o...
Glycerol and glycerol-3-phosphate: multifaceted metabolites in metabolism, cancer and other diseases [0.03%]
甘油和甘油-3-磷酸：代谢、癌症及其他疾病中的多功能代谢产物
S R Murthy Madiraju,Elite Possik,Fahd Al-Mulla et al.
S R Murthy Madiraju et al.
Glycerol and glycerol-3-phosphate are key metabolites at the intersection of carbohydrate, lipid and energy metabolism. Their production and usage are organismal and cell type specific. Glycerol has unique physicochemical properties enablin...
Cognitive Assessment in Adults with Adrenal Cortisol Insufficiency: Challenges and Opportunities [0.03%]
成人肾上腺皮质醇不足的认知评估：挑战与机遇
Anat Ben-Shlomo,Michelle Koh,Sarah A Kremen et al.
Anat Ben-Shlomo et al.
Adults with adrenal cortisol insufficiency (ACI) often report cognitive dysfunction, especially in memory processing and executive function. Only a few studies have objectively compared cognitive function as the primary outcome between pati...