UPLC-MS/MS Combined with Microdialysis for Determination of Two Active Components of Chuanxiong Rhizoma Extracts in Rat Brain: Application in Pharmacokinetic Study [0.03%]
结合微透析的UPLC-MS/MS法测定川芎提取物中两种有效成分在大鼠脑内的分布及其药动学研究
Yu Wang,Liang Jin,Xinhua Liu et al.
Yu Wang et al.
Chuanxiong Rhizoma (Chuanxiong), a traditional Chinese medicine, has been widely used to treat various nervous and cardiovascular system-related conditions. Its active components, senkyunolide A (SA) and 3-n-butylphthalide (NBP), have been ...
Development and Validation of Rapid and Cost-Effective RP-HPLC/UV Method for Determination of Cetirizine/Levocetirizine in Blood Plasma of Smokers and Non Smokers: a Two Cohort Comparative Study [0.03%]
开发和验证快速且低成本的RP-HPLC/UV方法，用于测定吸烟者和非吸烟者血浆中西替利嗪/左旋西替利嗪的含量：一项两队列比较研究
Mashal Khattak,Zafar Iqbal,Asif Jan et al.
Mashal Khattak et al.
In this research study, a simple, rapid, sensitive, and cost-effective Reverse Phase High Performance Liquid Chromatography method was developed and validated for determination of Cetirizine and Levocetirizine in human plasma. The drugs wer...
A General Strategy to Rapid and Sensitive Determination of Five High Boiling Point Solvents in Pharmaceuticals by RP-HPLC Combined with Precipitation Method [0.03%]
一种用于药品中五种高沸点溶剂快速灵敏检测的RP-HPLC结合沉淀法通用策略研究
Chenxia Zhang,Zeyi Wu,Meiyan Qiu et al.
Chenxia Zhang et al.
The difficulty on determination of high boiling point solvents, always exist due to their low vapor pressure in headspace (HS) vial. What's worse, the commonly used GC diluents, such as N, N-dimethylacetamide, 1,3-dimethyl-2-imidazolidinone...
Rapid Characterization and Identification of the Chemical Constituents in San-Huang-Xie-Xin-Tang, a Traditional Chinese Medicine Formula, by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry [0.03%]
基于高效液相色谱与电喷雾串联四极杆飞行时间质谱的三黄泻心汤化学成分快速分析及鉴定
Lei Liu,Pei Hu,Mengmo Chen et al.
Lei Liu et al.
San-Huang-Xie-Xin-Tang (SHXXT), a traditional Chinese medicine formula composed of Coptidis rhizome (CR), Scutellariae radix (SR) and Rhei rhizome (RR), is widely used to treat hypertension, gastritis and peptic ulcer clinically. However, t...
Application of Polydopamine-Based Magnetic Solid-Phase Extraction for Highly Sensitive Determination of Aristolochic Acid I from Traditional Chinese Medicine Samples [0.03%]
基于聚多巴胺的磁固相萃取技术在传统中药样品中高效灵敏测定马兜铃酸I的应用研究
Huimin Li,Huina Cao,Zixin Zhang et al.
Huimin Li et al.
A low cost-effective and simple synthesis method combining magnetic solid-phase extraction (MSPE) and high-pressure liquid chromatography was developed for the analysis of aristolochic acids I (AAI) in traditional Chinese medicine samples. ...
Determination of Residual Dimethyl Sulfate in Cephalosporin Using HS-SPME/GC-MS [0.03%]
头孢类药物中残余二甲亚砜的HS-SPME/GCMS检测方法
Rongchun Lu
Rongchun Lu
Dimethyl sulfate (DMS) is widely used in manufacturing process but because of its genotoxicity nature, it should be monitored at trace levels (1 μg/mL). It is complicated and difficult to quantify DMS in cephalosporin with traditional meth...
Fast Determination of Propofol in Human Plasma Using C18-Functionalized Magnetic Nanomaterials Followed by Supercritical Fluid Chromatography [0.03%]
一种基于超临界流体色谱法和C18功能化磁性纳米材料的丙泊酚快速测定新方法研究
Shan-Yan Liang,Xiao-Min Xu,Peng Wang et al.
Shan-Yan Liang et al.
Novel C18-functionalized magnetic nanomaterials; i.e., C18@poly-styrene-divinylbenzene-glycidyl methacrylate-Fe3O4 (C18@PS-DVB-GMA-Fe3O4) have been synthesized by using N, N-dimethyloctadecylamine as modifying agent, which could be benefici...
RP-HPLC Study of the Complexation of Acetamiprid, Imidacloprid and Carboxin Guest Molecules With Thiophosphorylated Calix [6] Arene in Dimethylformamide-Acetonitrile-Water Mobile Phase [0.03%]
噻吩磷化杯[6]芳烃柱状基底与乙酰胺吡啶、沙拉assin和甲霜灵形成配合物的反相高效液相色谱研究
Chandramauly R Sharma,Vijay Mishra,Yadvendra Agrawal
Chandramauly R Sharma
Reversed-phase high-performance liquid chromatography was used to study the host-guest complexation of thiophosphacalixarenes (TPC 1-3) with acetamiprid, imidacloprid and carboxin as guests. The Onyx Monolithic C 18 column (150 × 0.1 mm) a...
Preparation of Chiral Stationary Phase Based on 1,1'-bi-2-Naphthol for Chiral Enantiomer Separation [0.03%]
基于1,1'-手性柱的制备及其对映体分离性能研究
Kun Fan,Rui Dong,Wenqing Hou et al.
Kun Fan et al.
Two enantiomeric novel chiral stationary phases (CSPs) R-3-Amide-BINOL CSP (CSP-1) and S-3-Amide-BINOL CSP (CSP-2) were prepared using (R/S)-1,1'-bi-2-naphthol (BINOL) derivatives as chiral selectors. The structure of CSPs was characterized...
Novel Green Chromatographic Approaches for Estimation of a Triple Common Cold Pharmaceutical Combination [0.03%]
一种新型的绿色色谱法用于测定普通感冒复方制剂中活性成分的含量研究
Rabab M Soliman,Yasmin Rostom,Yasmin M Fayez et al.
Rabab M Soliman et al.
Nowadays, there is a strong interest in the scientific community in developing innovative methodologies within a green analytical chemistry framework. Herein, we introduce the first chromatographic approaches for the concurrent estimation o...