Determination of Residual Dimethyl Sulfate in Cephalosporin Using HS-SPME/GC-MS
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Dimethyl sulfate (DMS) is widely used in manufacturing process but because of its genotoxicity nature, it should be monitored at trace levels (1 μg/mL). It is complicated and difficult to quantify DMS in cephalosporin with traditional method. Herein, a method... ...