Development of an in-house control standard for quantitative polymerase chain reaction-based diagnosis of leprosy [0.03%]
Selfu Girma,Mesfin Tafesse Gemeda,Adugna Abdi Woldesemayat et al.
Selfu Girma et al.
Introduction: To develop an in-house reference control DNA standard targeting the RLEP region of Mycobacterium leprae for use in quantitative polymerase chain reaction (qPCR) diagnostics, aiming to reduce dependence on an...
A liquid chromatography-tandem mass spectrometry method for therapeutic drug monitoring of treosulfan [0.03%]
Jeayeon Ryu,Sollip Kim,Sang-Hee Lee et al.
Jeayeon Ryu et al.
Introduction: Treosulfan is an alkylating agent administered before hematopoietic stem cell transplantation. Because pharmacokinetic parameters exhibit interindividual variability, therapeutic drug monitoring may be neces...
Systematic investigation of population-wide elevation in serum uric acid among military conscripts: development of a traceable laboratory quality control framework [0.03%]
Xianmin Lv,Yulian Li,Luwei Yan et al.
Xianmin Lv et al.
Introduction: A collective elevation in serum uric acid levels was detected among 98 military conscripts during routine physical examinations. This study aimed to determine the underlying causes and establish a traceable ...
Antibody screening for red blood cell alloimmunization in patients with chronic kidney disease undergoing hemodialysis in Arak, Iran [0.03%]
Maryam Yavari,Saeed Hassani,Mahmood Khosravi et al.
Maryam Yavari et al.
Introduction: This study aimed to investigate the prevalence of red blood cell (RBC) alloimmunization in hemodialysis-dependent patients with chronic kidney disease (CKD) in Arak, Iran. There is a paucity of incidence dat...
High-performance liquid chromatography screening reveals HbS/β+-thalassemia double heterozygosity as a pediatric muscular dystrophy mimic [0.03%]
高效液相色谱筛选发现HbS/β⁺-地中海贫血双重杂合子作为儿科肌营养不良的模拟病例
Carlos López-Medina,Isabel M Portell-Rigo,Virginia González-Iribarren et al.
Carlos López-Medina et al.
Introduction: Compound hemoglobinopathies may present with variable clinical phenotypes, particularly when additional genetic modifiers coexist. Sickle cell hemoglobin (HbS)/β+-thalassemia can mimic other pediatric condi...
Impact of SARS-CoV-2 vaccination on CD4+ and CD8+ T lymphocyte profiles in an HIV-positive and HIV-negative female cohort [0.03%]
SARS-CoV-2疫苗对HIV阳性及阴性女性队列的CD4+和CD8+T淋巴细胞谱型的影响
Olive Khaliq,Niren Maharaj,Mikyle David et al.
Olive Khaliq et al.
Introduction: The COVID-19 pandemic led to rapid global vaccine deployment, especially among high-risk groups, such as individuals living with HIV. Data are limited, however, on the immunologic effects of SARS-CoV-2 vacci...
Communication of newly diagnosed monoclonal gammopathy as a quasi-critical laboratory value [0.03%]
新发现单克隆免疫球蛋白的检验结果危急值报告沟通研究
Gurmukh Singh,Roni J Bollag,Natasha M Savage et al.
Gurmukh Singh et al.
Suspicious bands in serum and urine protein immunofixation electrophoresis tests in patients with and without a history of monoclonal gammopathies: a retrospective database study [0.03%]
有无单克隆丙球病史患者血和尿蛋白免疫固定电泳检测中可疑带的原因分析：数据库回顾性研究
Merve Dincer,Ozgur Aydin,Volkan Karakus et al.
Merve Dincer et al.
Introduction: Electrophoresis tests are reported as negative, positive, or-rarely-as suspicious for monoclonal band (SfMB). This study aimed to determine the fate of patients with SfMB findings in long-term follow-up. ...
Leukocyte telomere length and chronic disease burden in an adult community sample: a cross-sectional study [0.03%]
来自成人社区样本的白细胞端粒长度与慢性疾病负担：一项横断面研究
Jerome Alfred Q Tabajonda,Shang-Hsien Yang,Yi-Ling Shen et al.
Jerome Alfred Q Tabajonda et al.
Introduction: Telomere length is a biomarker of cellular aging and chronic disease risk, but its population-level correlates and disease-specific patterns remain unclear. This study examined telomere length associations a...
Colorimetric LAMP assay enables rapid detection of Hb Lepore and Hb Sicilian deletions in the β-globin gene cluster with minimal instrumentation [0.03%]
一种基于环介导等温扩增技术的比色法，可在无需复杂仪器的情况下实现β-球蛋白基因簇中Hb Lepore和Hb Sicilian缺失突变的快速检测
Leila Riahi,Mohsen Golabi,Hossein Jalali
Leila Riahi
Introduction: Accurate and timely detection of hemoglobin (Hb) variants, including Hb Lepore and Hb Sicilian, is crucial for diagnosing and managing β-thalassemia. This study aimed to develop a simple and rapid colorimet...