Proximate larval epidermal cell layer generates forces for Pupal thorax closure in Drosophila [0.03%]
果蝇蛹期胸节闭合由近端幼虫表皮细胞层产生力来驱动
Thamarailingam Athilingam,Saurabh S Parihar,Rachita Bhattacharya et al.
Thamarailingam Athilingam et al.
During tissue closures, such as embryonic dorsal closure in Drosophila melanogaster, a proximate extra-embryonic layer, amnioserosa, generates forces that drive migration of the flanking lateral embryonic epidermis, thereby zip-shutting the...
Brian Charlesworth
Brian Charlesworth
The effects of selection on variability at linked sites have an important influence on levels and patterns of within-population variation across the genome. Most theoretical models of these effects have assumed that selection is sufficientl...
Improving genomic predictions with inbreeding and nonadditive effects in two admixed maize hybrid populations in single and multienvironment contexts [0.03%]
利用近交和非加性效应改进两个杂种玉米群体的单环境及多环境背景下泛基因组预测能力
Morgane Roth,Aurélien Beugnot,Tristan Mary-Huard et al.
Morgane Roth et al.
Genetic admixture, resulting from the recombination between structural groups, is frequently encountered in breeding populations. In hybrid breeding, crossing admixed lines can generate substantial nonadditive genetic variance and contraste...
Fitness benefits play a vital role in the retention of the Pi-ta susceptible alleles [0.03%]
适合度效应在Pt抗病等位基因保留中的作用
Jia Liu,Suobing Zhang,Pengfei Xie et al.
Jia Liu et al.
In plants, large numbers of R genes, which segregate as loci with alternative alleles conferring different levels of disease resistance to pathogens, have been maintained over a long period of evolution. The reason why hosts harbor suscepti...
A numerical framework for genetic hitchhiking in populations of variable size [0.03%]
数值框架：大小可变种群中的基因搭便现象
Eric Friedlander,Matthias Steinrücken
Eric Friedlander
Natural selection on beneficial or deleterious alleles results in an increase or decrease, respectively, of their frequency within the population. Due to chromosomal linkage, the dynamics of the selected site affect the genetic variation at...
The utility of a closed breeding colony of Peromyscus leucopus for dissecting complex traits [0.03%]
封闭繁殖的田鼠（白足鼠）种群在解析复杂性状中的应用价值分析
Phillip N Long,Vanessa J Cook,Arundhati Majumder et al.
Phillip N Long et al.
Deermice of the genus Peromyscus are well suited for addressing several questions of biologist interest, including the genetic bases of longevity, behavior, physiology, adaptation, and their ability to serve as disease vectors. Here, we exp...
Single-cell Iso-Sequencing enables rapid genome annotation for scRNAseq analysis [0.03%]
单细胞等位基因序列信息快速注释scRNAseq分析中的基因组信息
Hope M Healey,Susan Bassham,William A Cresko
Hope M Healey
Single-cell RNA sequencing is a powerful technique that continues to expand across various biological applications. However, incomplete 3'-UTR annotations can impede single-cell analysis resulting in genes that are partially or completely u...
ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans [0.03%]
新型的与CDK-5相互作用结合蛋白CCD-5调控秀丽隐杆线虫腹神经索引导先行轴突指引方向
Abigail H Feresten,Jaffar M Bhat,Alex J Yu et al.
Abigail H Feresten et al.
During nervous system development, axons navigate complex environments to reach synaptic targets. Early extending axons must interact with guidance cues in the surrounding tissue, while later extending axons can interact directly with earli...
Anton Gartner,JoAnne Engebrecht
Anton Gartner
DNA must be accurately copied and propagated from one cell division to the next, and from one generation to the next. To ensure the faithful transmission of the genome, a plethora of distinct as well as overlapping DNA repair and recombinat...
A complex genetic architecture underlies mandibular evolution in big mice from Gough Island [0.03%]
库格岛大鼠类动物下颌进化的复杂遗传结构
Michelle D Parmenter,Jacob P Nelson,Melissa M Gray et al.
Michelle D Parmenter et al.
Some of the most compelling examples of morphological evolution come from island populations. Alterations in the size and shape of the mandible have been repeatedly observed in murid rodents following island colonization. Despite this patte...