STRIPAK regulation of katanin microtubule severing in the Caenorhabditis elegans embryo [0.03%]
STRIPAK对秀丽隐杆线虫胚胎中katanin微管切割的调节作用
Tammy Lu,Ryan B Smit,Hanifa Soueid et al.
Tammy Lu et al.
Microtubule severing plays important role in cell structure and cell division. The microtubule severing protein katanin, composed of the MEI-1/MEI-2 subunits in Caenorhabditis elegans, is required for oocyte meiotic spindle formation; howev...
Properties of 2-locus genealogies and linkage disequilibrium in temporally structured samples [0.03%]
具有时间结构样本的双位点基因组和连锁不平衡性质
Arjun Biddanda,Matthias Steinrücken,John Novembre
Arjun Biddanda
Archeogenetics has been revolutionary, revealing insights into demographic history and recent positive selection. However, most studies to date have ignored the nonrandom association of genetic variants at different loci (i.e. linkage diseq...
Functional variability in adhesion and flocculation of yeast megasatellite genes [0.03%]
芽囊酵母基因组巨型卫星dna的功能变异及其在黏附和絮凝中的作用
Cyril Saguez,David Viterbo,Stéphane Descorps-Declère et al.
Cyril Saguez et al.
Megasatellites are large tandem repeats found in all fungal genomes but especially abundant in the opportunistic pathogen Candida glabrata. They are encoded in genes involved in cell-cell interactions, either between yeasts or between yeast...
L Sian Gramates,Julie Agapite,Helen Attrill et al.
L Sian Gramates et al.
FlyBase provides a centralized resource for the genetic and genomic data of Drosophila melanogaster. As FlyBase enters our fourth decade of service to the research community, we reflect on our unique aspects and look forward to our continue...
The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in Caenorhabditis elegans [0.03%]
锌指转录因子LSL-1是调节秀丽隐杆线虫生殖系 transcriptional程序的主要调节因子
David Rodriguez-Crespo,Magali Nanchen,Shweta Rajopadhye et al.
David Rodriguez-Crespo et al.
Specific gene transcriptional programs are required to ensure the proper proliferation and differentiation processes underlying the production of specialized cells during development. Gene activity is mainly regulated by the concerted actio...
Monique Lillis,Nathan J Zaccardi,Maxwell G Heiman
Monique Lillis
Cells are highly organized machines with functionally specialized compartments. For example, membrane proteins are localized to axons or dendrites in neurons and to apical or basolateral surfaces in epithelial cells. Interestingly, many sen...
Bipin Kumar Tripathi,Kenneth D Irvine
Bipin Kumar Tripathi
The Drosophila wing imaginal disc is a tissue of undifferentiated cells that are precursors of the wing and most of the notum of the adult fly. The wing disc first forms during embryogenesis from a cluster of ∼30 cells located in the secon...
Brian Charlesworth
Brian Charlesworth
R.A. Fisher's 1922 paper On the dominance ratio has a strong claim to be the foundation paper for modern population genetics. It greatly influenced subsequent work by Haldane and Wright, and contributed 3 major innovations to the study of e...
Taking flight: an educational primer for use with "A novel mechanism for activation of myosin regulatory light chain by protein kinase C-delta in Drosophila" [0.03%]
展翅飞翔：教授文章“A novel mechanism for activation of myosin regulatory light chain by protein kinase C-delta in Drosophila”所用的教学指导书
Scott J Nowak,Krista C Dobi
Scott J Nowak
Muscles are required for animal movement, feeding, heartbeat, and reproduction. Disruption of muscle function can lead to mobility impairments and diseases like muscular dystrophy and cardiac myopathy; therefore, research in this area has s...
Germ granules and gene regulation in the Caenorhabditis elegans germline [0.03%]
模式动物线虫中的生殖细胞基因表达调控及其遗传机制研究
Carolyn M Phillips,Dustin L Updike
Carolyn M Phillips
The transparency of Caenorhabditis elegans provides a unique window to observe and study the function of germ granules. Germ granules are specialized ribonucleoprotein (RNP) assemblies specific to the germline cytoplasm, and they are largel...