MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses [0.03%]
基于网络的多本体和多物种分析基因集富集工具在RGD上的应用（MOET）
Mahima Vedi,Harika S Nalabolu,Chien-Wei Lin et al.
Mahima Vedi et al.
Biological interpretation of a large amount of gene or protein data is complex. Ontology analysis tools are imperative in finding functional similarities through overrepresentation or enrichment of terms associated with the input gene or pr...
JaponicusDB: rapid deployment of a model organism database for an emerging model species [0.03%]
JaponicusDB：新兴模型物种模式生物数据库的快速部署
Kim M Rutherford,Midori A Harris,Snezhana Oliferenko et al.
Kim M Rutherford et al.
The fission yeast Schizosaccharomyces japonicus has recently emerged as a powerful system for studying the evolution of essential cellular processes, drawing on similarities as well as key differences between S. japonicus and the related, w...
Ubiquitin ligases and a processive proteasome facilitate protein clearance during the oocyte-to-embryo transition in Caenorhabditis elegans [0.03%]
ubiquitin蛋白酶体在促进秀丽隐杆线虫卵母细胞到胚胎过渡期间的蛋白质清除中的作用
Caroline A Spike,Tatsuya Tsukamoto,David Greenstein
Caroline A Spike
The ubiquitin-mediated degradation of oocyte translational regulatory proteins is a conserved feature of the oocyte-to-embryo transition. In the nematode Caenorhabditis elegans, multiple translational regulatory proteins, including the TRIM...
Noggin proteins are multifunctional extracellular regulators of cell signaling [0.03%]
Noggin蛋白是细胞信号传导的多功能胞外调节因子
Prashath Karunaraj,Olivia Tidswell,Elizabeth J Duncan et al.
Prashath Karunaraj et al.
Noggin is an extracellular cysteine knot protein that plays a crucial role in vertebrate dorsoventral patterning. Noggin binds and inhibits the activity of bone morphogenetic proteins via a conserved N-terminal clip domain. Noncanonical ort...
The PH/MyTH4/FERM molecule MAX-1 inhibits UNC-5 activity in the regulation of VD growth cone protrusion in Caenorhabditis elegans [0.03%]
C. elegans 中 MAX-1 蛋白通过抑制UNC-5活性调控VD类神经元生长锥的侧向伸出
Snehal S Mahadik,Erik A Lundquist
Snehal S Mahadik
UNC-6/Netrin is a secreted conserved guidance cue that regulates dorsal-ventral axon guidance of Caenorhabditis elegans and in the vertebral spinal cord. In the polarity/protrusion model of VD growth cone guidance away from ventrally expres...
The Mnn10/Anp1-dependent N-linked outer chain glycan is dispensable for Candida albicans cell wall integrity [0.03%]
酿酒酵母假丝酵母细胞壁的完整性不需要Mnn10 / Anp1依赖性的N连接的外链糖链
Neta Dean,Rachel Jones,Justin DaSilva et al.
Neta Dean et al.
Candida albicans cell wall glycoproteins, and in particular their mannose-rich glycans, are important for maintaining cellular integrity as well as host recognition, adhesion, and immunomodulation. The asparagine (N)-linked mannose outer ch...
Evaluation of methods for estimating coalescence times using ancestral recombination graphs [0.03%]
利用祖先重组图估计合并时间的方法评估
Débora Y C Brandt,Xinzhu Wei,Yun Deng et al.
Débora Y C Brandt et al.
The ancestral recombination graph is a structure that describes the joint genealogies of sampled DNA sequences along the genome. Recent computational methods have made impressive progress toward scalably estimating whole-genome genealogies....
Divergent regulatory roles of NuRD chromatin remodeling complex subunits GATAD2 and CHD4 in Caenorhabditis elegans [0.03%]
GATAD2和CHD4在秀丽隐杆线虫中NuRD染色质重塑复合体中的不同调节作用
Nicole L Golden,Michaela K Foley,Karen S Kim Guisbert et al.
Nicole L Golden et al.
During proteotoxic stress, a pathway known as the heat shock response is induced to maintain protein-folding homeostasis or proteostasis. Previously, we identified the Caenorhabditis elegans GATAD2 ortholog, dcp-66, as a novel regulator of ...
Nematode chromosomes [0.03%]
线虫染色体
Peter M Carlton,Richard E Davis,Shawn Ahmed
Peter M Carlton
The nematode Caenorhabditis elegans has shed light on many aspects of eukaryotic biology, including genetics, development, cell biology, and genomics. A major factor in the success of C. elegans as a model organism has been the availability...
The Nup2 meiotic-autonomous region relieves inhibition of Nup60 to promote progression of meiosis and sporulation in Saccharomyces cerevisiae [0.03%]
芽丝虫草酒酵母Nup2 meio自主区通过释放对Nup60的抑制促进减数分裂及有性孢子形成
Kelly Komachi,Sean M Burgess
Kelly Komachi
During meiosis, chromosomes undergo dramatic changes in structural organization, nuclear positioning, and motion. Although the nuclear pore complex has been shown to affect genome organization and function in vegetative cells, its role in m...