VIDEO - Visual Integration of Drosophila Enhancer Organization: A tool for integrating and visualizing chromatin accessibility, in vivo transcription factor binding and motif occurrence in tissue-specific differentially expressed genes [0.03%]
视频-VIDEO：整合和可视化果蝇增强子组织的工具：染色质可访问性、体内转录因子结合和特异性表达基因中的基序发生的整合和可视化工具
Vidya Ajay,Nathaniel Laughner,Patrick Cahan et al.
Vidya Ajay et al.
Dissecting gene regulation today relies on many genomic assays - including transcriptional output from RNA-seq, chromatin accessibility from ATAC-seq, and transcription factor (TF) binding from ChIP-seq. Whereas numerous tools exist for eac...
Auxin promotes robust founder cell specification during Arabidopsis lateral root initiation [0.03%]
生长素在拟南芥侧根起始过程中的创始人细胞指定中的作用
Cassandra Maranas,Sydney VanGilder,Linda Nguyen et al.
Cassandra Maranas et al.
Cell-to-cell variation in gene expression can be highly detrimental and, in some contexts, is actively buffered out; however, in other contexts, it is crucial and actively amplified. For example, variation must be minimized to build organs ...
A new mathematical model for genetic linkage and recombination of haploid virus populations [0.03%]
单倍体病毒种群遗传连锁和重组的新数学模型
Patrick J Feehley,Michael C Feehley,Zih-Yu Hsieh et al.
Patrick J Feehley et al.
Linkage disequilibrium (LD), logarithm of the odds (LOD), and recombination frequency (Rf) have long been measured independently. However, their relationship in viral haploid recombination has not been fully understood due to the unavailabi...
Residual double strand break repair during meiosis in budding yeast is promoted by PIF1, RAD54 and RDH54/TID1 [0.03%]
PIF1、RAD54和RDH54/TID1促进芽殖酵母减数分裂过程中剩余的双链断裂修复
Raunak Dutta,Lihong Wan,David Murtha et al.
Raunak Dutta et al.
In the budding yeast, Saccharomyces cerevisiae, repair of programmed double strand breaks occurs in two phases during prophase I of meiosis. During Phase 1 interhomolog recombination is mediated by the meiosis-specific Dmc1 recombinase. Cro...
Fluorescent organelle markers in Cryptococcus neoformans: a versatile toolkit for live-cell subcellular localization [0.03%]
新孢子虫荧光细胞器标记物：活细胞亚细胞定位的有力工具包
Yeseul Choi,Yong-Sun Bahn,Joseph Heitman
Yeseul Choi
Understanding how intracellular organelles are organized and dynamically remodeled is essential for elucidating fungal growth, differentiation, and pathogenicity. The human fungal pathogen Cryptococcus neoformans exhibits remarkable morphol...
Comparative genomic analysis and epigenetic profiling of the Drosophila melanogaster B chromosome [0.03%]
模式生物丝氨酸棕图染色体的基因组分析及表观遗传学特征研究
Ana B S M Ferretti,Diogo Milani,Emiliano Martí et al.
Ana B S M Ferretti et al.
Supernumerary B chromosomes have been identified in hundreds of species across many different taxa, each with their own evolutionary history, unique sequence composition, and epigenetic profile. In this study, we generated a detailed repeti...
Multi-trait genomic prediction method in approximate genome-based kernel model [0.03%]
基于约简核模型的多性状基因组预测方法
Hailan Liu,Hai Lan
Hailan Liu
In order to cultivate excellent varieties, breeders need to evaluate multiple traits simultaneously. In this study, we developed an efficient large-scale multi-trait genomic prediction method in approximate genome-based kernel model (MT-RHP...
Pangenomes reveal extensive structural variation in a suboscine passerine bird, the Pearly-vented Tody-Tyrant (Hemitriccus margaritaceiventer) [0.03%]
泛基因组揭示了一种扇尾莺科鸣鸟——珠胁隐短翅娇虎凤头鹦（Hemitriccus margaritaceiventer）中广泛存在的结构变异
Kelsie A Lopez,Clarissa Ferreira de Carvalho,Hevana Santana de Lima et al.
Kelsie A Lopez et al.
Structural variants (SV) are major drivers of evolutionary processes such as adaptation and speciation, yet their complexity and dynamics in wild populations remain largely unexplored. Avian diversity is highest in the Neotropics, primarily...
Pervasive suppressors halt the spread of selfish Segregation Distorter in a natural population [0.03%]
泛在抑制者阻止天然种群中自私分离失真基因的传播
Ching-Ho Chang,Tyler Handler,Nick Fuda et al.
Ching-Ho Chang et al.
Meiotic drivers are selfish genetic elements that subvert Mendelian inheritance to increase their own transmission, yet they are typically found at low frequencies across natural populations. The factors that limit their spread remain uncle...
Multilevel transcriptional regulation of embryonic sex determination and dosage compensation by the X-signal element sex-1 [0.03%]
X信号元件sex-1介导的胚胎性别决定与剂量补偿多层次转录调控机制研究
Eshna Jash,Zoey M Tan,Audry I Rakozy et al.
Eshna Jash et al.
The C. elegans nuclear hormone receptor sex-1 is an embryonic X-signal element that represses xol-1, the sex-switch gene that is the master regulator of sex determination and dosage compensation. Several prior studies on sex-1 function have...