James E Haber
James E Haber
More than 20 years before DNA was identified as the hereditary material, the Drosophila geneticist, Hermann Muller, envisioned the fundamental principles that such a molecule must have: to be auto-assembling and to be mutable but then again...
Methylation of CENP-A/Cse4 on arginine 143 and lysine 131 regulates kinetochore stability in yeast [0.03%]
甲硫氨酸CENP-A/Cse4在酵母染色体着丝粒稳定性中的调节作用
Tra My Tran Nguyen,Arno Munhoven,Anke Samel-Pommerencke et al.
Tra My Tran Nguyen et al.
Post-translational modifications on histones are well known to regulate chromatin structure and function, but much less information is available on modifications of the centromeric histone H3 variant and their effect at the kinetochore. Her...
Extensive crop-wild hybridization during Brassica evolution and selection during the domestication and diversification of Brassica crops [0.03%]
白菜类作物驯化和多样性进化过程中普遍存在与野生近缘种杂交现象
Jasmine M Saban,Anne J Romero,Thomas H G Ezard et al.
Jasmine M Saban et al.
Adaptive genetic diversity in crop wild relatives (CWRs) can be exploited to develop improved crops with higher yield and resilience if phylogenetic relationships between crops and their CWRs are resolved. This further allows accurate quant...
Multispecies polyploidization, chromosome shuffling, and genome extraction in Zea/Tripsacum hybrids [0.03%]
基于玉米和簇毛谷子的多物种多倍体杂交后代中的染色体重组及基因组提取事件分析
Muhammad Zafar Iqbal,Xiaodong Wen,Lulu Xu et al.
Muhammad Zafar Iqbal et al.
By hybridization and special sexual reproduction, we sequentially aggregated Zea mays, Zea perennis, and Tripsacum dactyloides in an allohexaploid, backcrossed it with maize, derived self-fertile allotetraploids of maize and Z. perennis by ...
Transcriptomic profiling of sex-specific olfactory neurons reveals subset-specific receptor expression in Caenorhabditis elegans [0.03%]
秀丽杆线虫性别特异性嗅觉神经元的功能研究及受体表达谱分析
Douglas K Reilly,Erich M Schwarz,Caroline S Muirhead et al.
Douglas K Reilly et al.
The nematode Caenorhabditis elegans utilizes chemosensation to navigate an ever-changing environment for its survival. A class of secreted small-molecule pheromones, termed ascarosides, play an important role in olfactory perception by affe...
Genome-wide analysis reveals novel regulators of synaptic maintenance in Drosophila [0.03%]
全基因组分析揭示了果蝇新的突触维持调节因子
Jessica M Sidisky,Danielle de Paula Moreira,Meryem Okumus et al.
Jessica M Sidisky et al.
Maintaining synaptic communication is required to preserve nervous system function as an organism ages. While much work has been accomplished to understand synapse formation and development, we understand relatively little regarding maintai...
Parallel expansion and divergence of an adhesin family in pathogenic yeasts [0.03%]
致病性酵母中黏附素家族的并行扩张及分化
Rachel A Smoak,Lindsey F Snyder,Jan S Fassler et al.
Rachel A Smoak et al.
Opportunistic yeast pathogens arose multiple times in the Saccharomycetes class, including the recently emerged, multidrug-resistant (MDR) Candida auris. We show that homologs of a known yeast adhesin family in Candida albicans, the Hyr/Iff...
Deviations in the Z:A ratio disrupt sexual development in the eri silkmoth, Samia cynthia ricini [0.03%]
Z:A染色体比值的改变会干扰丽纹羽蛾的性别分化
Atsuo Yoshido,František Marec
Atsuo Yoshido
Moths and butterflies (Lepidoptera) have sex chromosome systems with female heterogamety, and 2 models, W-dominance and Z-counting, have been proposed to determine sex. The W-dominant mechanism is well known in Bombyx mori. However, little ...
Caenorhabditis elegans spermatocytes can segregate achiasmate homologous chromosomes apart at higher than random frequency during meiosis I [0.03%]
秀丽隐杆线虫雄性减数第一次分裂过程中同源染色体在没有形成联会复合体的情况下能够以高于随机的概率正确分离
Ting Gong,Francis J McNally
Ting Gong
Chromosome segregation errors during meiosis are the leading cause of aneuploidy. Faithful chromosome segregation during meiosis in most eukaryotes requires a crossover which provides a physical attachment holding homologs together in a "bi...
Modeling the genetic footprint of fluctuating balancing selection: from the local to the genomic scale [0.03%]
平衡选择的遗传特征建模：从局部到基因组尺度
Meike J Wittmann,Sylvain Mousset,Joachim Hermisson
Meike J Wittmann
Natural selection not only affects the actual loci under selection but also leaves "footprints" in patterns of genetic variation in linked genetic regions. This offers exciting opportunities for inferring selection and for understanding the...