Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice [0.03%]
Prdm9基因的锌指编码外显子中的自然变异会影响小鼠的杂交不育性状
Khawla F N AbuAlia,Elena Damm,Kristian K Ullrich et al.
Khawla F N AbuAlia et al.
PRDM9-mediated reproductive isolation was first described in the progeny of Mus musculus musculus (MUS) PWD/Ph and Mus musculus domesticus (DOM) C57BL/6J inbred strains. These male F1 hybrids fail to complete chromosome synapsis and arrest ...
Dynein directs prophase centrosome migration to control the stem cell division axis in the developing Caenorhabditis elegans epidermis [0.03%]
动力蛋白指导腹皮细胞有丝分裂过程中中心体向干细胞分裂极移动
Cátia Carvalho,Daniel J Barbosa,Ricardo Celestino et al.
Cátia Carvalho et al.
The microtubule motor dynein is critical for the assembly and positioning of mitotic spindles. In Caenorhabditis elegans, these dynein functions have been extensively studied in the early embryo but remain poorly explored in other developme...
A new hybrid incompatibility locus between Drosophila melanogaster and Drosophila sechellia [0.03%]
果蝇和塞席尔果蝇之间一个新的杂合不亲和性位点
Jackson Bladen,Jacob C Cooper,Jackson T Ridges et al.
Jackson Bladen et al.
Despite the fundamental importance of hybrid incompatibilities to the process of speciation, there are few cases where the evolution and genetic architecture of hybrid incompatibilities are understood. One of the longest studied hybrid inco...
Transcribed enhancer sequences are required for maize p1 paramutation [0.03%]
转录的增强子序列对于玉米p1等位基因的参数变异是必需的
Lyudmila V Sidorenko,Vicki L Chandler,Xiujuan Wang et al.
Lyudmila V Sidorenko et al.
Paramutation is a transfer of heritable silencing states between interacting endogenous alleles or between endogenous alleles and homologous transgenes. Prior results demonstrated that paramutation occurs at the P1-rr (red pericarp and red ...
Centromere-proximal suppression of meiotic crossovers in Drosophila is robust to changes in centromere number, repetitive DNA content, and centromere-clustering [0.03%]
果蝇中着丝粒附近的减数分裂交换受到着丝粒数量,重复DNA含量和着丝粒聚类变化的稳健抑制作用
Nila M Pazhayam,Leah K Frazier,Jeff Sekelsky
Nila M Pazhayam
Accurate segregation of homologous chromosomes during meiosis depends on both the presence and the regulated placement of crossovers (COs). The centromere effect, or CO exclusion in pericentromeric regions of the chromosome, is a meiotic CO...
Yali Sun,Yuman Yuan,Shoupu He et al.
Yali Sun et al.
Numerous genetic loci and several functionally characterized genes have been linked to determination of lint percentage (lint%), one of the most important cotton yield components, but we still know little about the major genetic components ...
The fitness consequences of genetic divergence between polymorphic gene arrangements [0.03%]
多态基因排列之间遗传分歧的适应性后果
Brian Charlesworth
Brian Charlesworth
Inversions restrict recombination when heterozygous with standard arrangements, but often have few noticeable phenotypic effects. Nevertheless, there are several examples of inversions that can be maintained polymorphic by strong selection ...
Complex epistatic interactions between ELF3, PRR9, and PRR7 regulate the circadian clock and plant physiology [0.03%]
ELF3,PRR9和PRR7之间的复杂上位性相互作用调节生物钟和植物生理学
Li Yuan,Paula Avello,Zihao Zhu et al.
Li Yuan et al.
Circadian clocks are endogenous timekeeping mechanisms that coordinate internal physiological responses with the external environment. EARLY FLOWERING3 (ELF3), PSEUDO RESPONSE REGULATOR (PRR9), and PRR7 are essential components of the plant...
Heterozygosity alters Msh5 binding to meiotic chromosomes in the baker's yeast [0.03%]
杂合性改变了酿酒酵母中Msh5与减数分裂染色体的结合
Suman Dash,Sameer Joshi,Ajith V Pankajam et al.
Suman Dash et al.
Meiotic crossovers are initiated from programmed DNA double-strand breaks. The Msh4-Msh5 heterodimer is an evolutionarily conserved mismatch repair-related protein complex that promotes meiotic crossovers by stabilizing strand invasion inte...