Human genetics of face recognition: discovery of MCTP2 mutations in humans with face blindness (congenital prosopagnosia) [0.03%]
人类面孔识别的遗传学：发现MCTP2基因突变导致脸盲症（先天性面孔失认症）
Yun Sun,Weiwei Men,Ingo Kennerknecht et al.
Yun Sun et al.
Face recognition is important for both visual and social cognition. While prosopagnosia or face blindness has been known for seven decades and face-specific neurons for half a century, the molecular genetic mechanism is not clear. Here we r...
A cytological F1 RNAi screen for defects in Drosophila melanogaster female meiosis [0.03%]
用于筛选缺陷的果蝇雌性减数分裂的F1 RNAi细胞学筛查
William D Gilliland,Dennis P May,Amelia O Bowen et al.
William D Gilliland et al.
Genetic screens for recessive alleles induce mutations, make the mutated chromosomes homozygous, and then assay those homozygotes for the phenotype of interest. When screening for genes required for female meiosis, the phenotype of interest...
Mouse Genome Informatics: an integrated knowledgebase system for the laboratory mouse [0.03%]
模式小鼠基因功能分析数据库
Richard M Baldarelli,Cynthia L Smith,Martin Ringwald et al.
Richard M Baldarelli et al.
Mouse Genome Informatics (MGI) is a federation of expertly curated information resources designed to support experimental and computational investigations into genetic and genomic aspects of human biology and disease using the laboratory mo...
What is new in FungiDB: a web-based bioinformatics platform for omics-scale data analysis for fungal and oomycete species [0.03%]
FungiDB最新功能介绍：一个用于真菌及壶菌物种的组学尺度数据分析的网络生物信息平台
Evelina Y Basenko,Achchuthan Shanmugasundram,Ulrike Böhme et al.
Evelina Y Basenko et al.
FungiDB (https://fungidb.org) serves as a valuable online resource that seamlessly integrates genomic and related large-scale data for a wide range of fungal and oomycete species. As an integral part of the VEuPathDB Bioinformatics Resource...
Fixation times of de novo and standing beneficial variants in subdivided populations [0.03%]
分层种群中新出现和已存在的有利突变的固定时间
Vitor Sudbrack,Charles Mullon
Vitor Sudbrack
The rate at which beneficial alleles fix in a population depends on the probability of and time to fixation of such alleles. Both of these quantities can be significantly impacted by population subdivision and limited gene flow. Here, we in...
Evolution and genetics of accessory gland transcriptome divergence between Drosophila melanogaster and D. simulans [0.03%]
果蝇(Drosophila melanogaster和D.simulans)辅助腺转录组分化的发展与遗传学研究
Alex C Majane,Julie M Cridland,Logan K Blair et al.
Alex C Majane et al.
Studies of allele-specific expression in interspecific hybrids have provided important insights into gene-regulatory divergence and hybrid incompatibilities. Many such investigations in Drosophila have used transcriptome data from complex m...
Expanding TheCellVision.org: a central repository for visualizing and mining high-content cell imaging projects [0.03%]
扩展TheCellVision.org：一个用于高内涵细胞影像项目的可视化和挖掘的中央仓库
Myra Paz David Masinas,Athanasios Litsios,Anastasia Razdaibiedina et al.
Myra Paz David Masinas et al.
We previously constructed TheCellVision.org, a central repository for visualizing and mining data from yeast high-content imaging projects. At its inception, TheCellVision.org housed two high-content screening (HCS) projects providing genom...
Characterization of the Pristionchus pacificus "epigenetic toolkit" reveals the evolutionary loss of the histone methyltransferase complex PRC2 [0.03%]
模式动物昆虫线虫帕西菲强棘尾线虫表观遗传系统的研究揭示了染色质修饰复合物PRC2的进化丢失
Audrey L Brown,Adriaan B Meiborg,Mirita Franz-Wachtel et al.
Audrey L Brown et al.
Comparative approaches have revealed both divergent and convergent paths to achieving shared developmental outcomes. Thus, only through assembling multiple case studies can we understand biological principles. Yet, despite appreciating the ...
Transcribing the enigma: the B chromosome as a territory of uncharted RNAs [0.03%]
破解谜团：B染色体作为未知RNA的区域
Jordana Inácio Nascimento Oliveira,Diogo C Cabral-de-Mello,Guilherme T Valente et al.
Jordana Inácio Nascimento Oliveira et al.
B chromosomes are supernumerary elements found in several groups of eukaryotes, including fungi, plants, and animals. Typically, these chromosomes either originate from their hosts through errors in meiosis or interspecifically through hori...
Naturally segregating genetic variants contribute to thermal tolerance in a Drosophila melanogaster model system [0.03%]
自然分隔的遗传变异体以果蝇（Drosophila melanogaster）模式系统为例促进热耐受性
Patricka A Williams-Simon,Camille Oster,Jordyn A Moaton et al.
Patricka A Williams-Simon et al.
Thermal tolerance is a fundamental physiological complex trait for survival in many species. For example, everyday tasks such as foraging, finding a mate, and avoiding predation are highly dependent on how well an organism can tolerate extr...