Extracellular vesicles [0.03%]
细胞外囊泡
Juan Wang,Maureen M Barr,Ann M Wehman
Juan Wang
Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differenti...
Calcium influx rapidly establishes distinct spatial recruitments of Annexins to cell wounds [0.03%]
钙离子迅速建立了细胞伤口处 Annexin 的不同空间募集效应
Mitsutoshi Nakamura,Susan M Parkhurst
Mitsutoshi Nakamura
To survive daily damage, the formation of actomyosin ring at the wound edge is required to rapidly close cell wounds. Calcium influx is one of the start signals for these cell wound repair events. Here, we find that rapid recruitment of all...
Genome size and chromosome number are critical metrics for accurate genome assembly assessment in Eukaryota [0.03%]
真核生物基因组组装评估的两个关键指标：基因组大小和染色体数量
Carl E Hjelmen
Carl E Hjelmen
The number of genome assemblies has rapidly increased in recent history, with NCBI databases reaching over 41,000 eukaryotic genome assemblies across about 2,300 species. Increases in read length and improvements in assembly algorithms have...
SHC-3: a previously unidentified C. elegans Shc family member functions in the insulin-like signaling pathway to enhance survival during L1 arrest [0.03%]
SHC-3：一个此前未被识别的秀丽杆线虫Shc家族成员通过作用于胰岛素信号传导通路提高L1停滞阶段的存活率
Mercedes Di Bernardo,Victoria L León Guerrero,Jacob C Sutoski et al.
Mercedes Di Bernardo et al.
Shc proteins function in many different signaling pathways where they mediate phosphorylation-dependent protein-protein interactions. These proteins are characterized by the presence of two phosphotyrosine-binding domains, an N-terminal PTB...
A spatial approach to jointly estimate Wright's neighborhood size and long-term effective population size [0.03%]
基于空间统计的Wright邻里大小和种群有效数估计方法
Zachary B Hancock,Rachel Toczydlowski,Gideon S Bradburd
Zachary B Hancock
Spatially continuous patterns of genetic differentiation, which are common in nature, are often poorly described by existing population genetic theory or methods that assume either panmixia or discrete, clearly definable populations. There ...
Estimating Genetic Variance Contributed by a Quantitative Trait Locus: Removing Nuisance Parameters [0.03%]
估计数量性状位点贡献的遗传方差：消除干扰参数
Shizhong Xu
Shizhong Xu
A main objective of mapping quantitative trait loci (QTL) and genome-wide association studies (GWAS) is to identify and locate QTLs on the genome. Estimating the sizes of QTL is equally important as identifying the QTLs. The size of a QTL i...
Gene duplication and evolutionary plasticity of lin-12/Notch gene function in Caenorhabditis [0.03%]
基因重复和模式动物线虫中lin-12/Notch基因功能的进化适应性研究进展
Haimeng Lyu,Nicolas D Moya,Erik C Andersen et al.
Haimeng Lyu et al.
Gene duplication is an important substrate for the evolution of new gene functions, but the impacts of gene duplicates on their own activities and on the developmental networks in which they act are poorly understood. Here, we use a natural...
Somatic epigenetic drift during shoot branching: a cell lineage-based model [0.03%]
基于细胞系的模型揭示了分枝过程中表观遗传漂变的现象
Yifan Chen,Agata Burian,Frank Johannes
Yifan Chen
Plant architecture is shaped by the production of new organs, most of which emerge post-embryonically. This process includes the formation of new lateral branches along existing shoots. Current evidence supports a detached meristem model as...
From heterosis to outbreeding depression: genotype-by-environment interaction shifts hybrid fitness in opposite directions [0.03%]
从杂种优势到近交衰退：基因型-环境互作使杂种适应性朝相反方向变化
Haolong Wang,Baofeng Su,Ying Zhang et al.
Haolong Wang et al.
In F1 hybrids, phenotypic values are expected to be near the parental means under additive effects or close to one parent under dominance. However, F1 traits can fall outside the parental range, and outbreeding depression occurs when inferi...
Susan Strome,Needhi Bhalla,Rohinton Kamakaka et al.
Susan Strome et al.
Gregor Mendel developed the principles of segregation and independent assortment in the mid-1800s based on his detailed analysis of several traits in pea plants. Those principles, now called Mendel's laws, in fact, explain the behavior of g...