DREAM interrupted: severing LIN-35-MuvB association in Caenorhabditis elegans impairs DREAM function but not its chromatin localization [0.03%]
干扰线虫中的LIN-35-MuvB相互作用不影响DREAM的染色质定位，但会损害其功能
Paul D Goetsch,Susan Strome
Paul D Goetsch
The mammalian pocket protein family, which includes the Retinoblastoma protein (pRb) and Rb-like pocket proteins p107 and p130, regulates entry into and exit from the cell cycle by repressing cell cycle gene expression. Although pRb plays a...
Reconstruction of full-length LINE-1 progenitors from ancestral genomes [0.03%]
从祖先基因组中重建完整的LINE-1始祖元件
Laura F Campitelli,Isaac Yellan,Mihai Albu et al.
Laura F Campitelli et al.
Sequences derived from the Long INterspersed Element-1 (L1) family of retrotransposons occupy at least 17% of the human genome, with 67 distinct subfamilies representing successive waves of expansion and extinction in mammalian lineages. L1...
BioKIT: a versatile toolkit for processing and analyzing diverse types of sequence data [0.03%]
BioKIT：用于处理和分析各种类型序列数据的多功能工具包
Jacob L Steenwyk,Thomas J Buida,Carla Gonçalves et al.
Jacob L Steenwyk et al.
Bioinformatic analysis-such as genome assembly quality assessment, alignment summary statistics, relative synonymous codon usage, file format conversion, and processing and analysis-is integrated into diverse disciplines in the biological s...
Translational suppression via IFG-1/eIF4G inhibits stress-induced RNA alternative splicing in Caenorhabditis elegans [0.03%]
IFG-1/eIF4G介导的翻译抑制作用可抑制秀丽隐杆线虫中的应激诱导RNA选择性剪接
Samantha C Chomyshen,Hadi Tabarraei,Cheng-Wei Wu
Samantha C Chomyshen
Splicing of precursor mRNA is an essential process for dividing cells, and splicing defects have been linked to aging and various chronic diseases. Environmental stress has recently been shown to modify alternative splicing, and molecular m...
A network modeling approach provides insights into the environment-specific yield architecture of wheat [0.03%]
一种网络建模方法有助于深入研究环境特异性的小麦产量结构
Noah DeWitt,Mohammed Guedira,Joseph Paul Murphy et al.
Noah DeWitt et al.
Wheat (Triticum aestivum) yield is impacted by a diversity of developmental processes which interact with the environment during plant growth. This complex genetic architecture complicates identifying quantitative trait loci that can be use...
Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sublines [0.03%]
细胞培养中的持续转座揭示了多种果蝇S2亚系的系统发育关系
Shunhua Han,Guilherme B Dias,Preston J Basting et al.
Shunhua Han et al.
Cultured cells are widely used in molecular biology despite poor understanding of how cell line genomes change in vitro over time. Previous work has shown that Drosophila cultured cells have a higher transposable element content than whole ...
Seed banks alter the molecular evolutionary dynamics of Bacillus subtilis [0.03%]
芽孢库改变了枯草芽孢杆菌的分子进化动力学
William R Shoemaker,Evgeniya Polezhaeva,Kenzie B Givens et al.
William R Shoemaker et al.
Fluctuations in the availability of resources constrain the growth and reproduction of individuals, which subsequently affects the evolution of their respective populations. Many organisms contend with such fluctuations by entering a revers...
Fatemeh Amini,Guiping Hu,Lizhi Wang et al.
Fatemeh Amini et al.
Selecting for multiple traits as opposed to a single trait has become increasingly important in genomic selection. As one of the most popular approaches to multitrait genomic selection, index selection uses a weighted average of all traits ...
Meiotic cDNA libraries reveal gene truncations and mitochondrial proteins important for competitive fitness in Saccharomyces cerevisiae [0.03%]
配子型cDNA文库揭示了酿酒酵母竞争适应性重要的基因截断及线粒体蛋白
Tina L Sing,Katie Conlon,Stephanie H Lu et al.
Tina L Sing et al.
Gametogenesis is an evolutionarily conserved developmental program whereby a diploid progenitor cell undergoes meiosis and cellular remodeling to differentiate into haploid gametes, the precursors for sexual reproduction. Even in the simple...
Dafang Wang,Chuanhe Yu,Jianbo Zhang et al.
Dafang Wang et al.
Eukaryotic Macrotransposons (MTns) can be formed by 2 nearby elements flanking a segment of host DNA. The maize Ac transposon can form Ac::MTns, but little is known about Ac::MTn transposition activities. Here, we studied 3 Ac::MTns at the ...