From Indirect Evidence to Head-to-Head Trials in Anticoagulation: Clinical Implications of the COBRRA Moment in DOAC Treatment [0.03%]
Andrej Belancic,Josip Andelo Borovac
Andrej Belancic
Underuse of Guideline-Directed Medical Therapy Across Heart Failure Phenotypes in Older Outpatients: A Multicenter Cross-Sectional Study in Vietnam [0.03%]
Huan Thanh Nguyen,Huong Thi Mai Nguyen,Kieu Dang Phuong Nguyen et al.
Huan Thanh Nguyen et al.
BackgroundHeart failure (HF) is common among older adults; however, data on phenotype distribution and real-world pharmacologic management remain limited. This study assessed the prevalence of guideline-directed medical therapy (GDMT) under...
Bringing Journal of Cardiovascular Pharmacology and Therapeutics (JCPT) to a Next Level: Strategies and Vision to Ensure a Sustained Journal Growth [0.03%]
带领《心血管药理学与治疗学杂志》（JCPT）走向新高度：确保期刊持续发展的策略和愿景
Josip Andelo Borovac
Josip Andelo Borovac
Factors Associated With the Selection of Anti-Hypertensive Medications: A Retrospective Cross-Sectional Analysis [0.03%]
高血压药物选择的影响因素：一项回顾性横断面研究分析
Aymen Alqurain,Arif Aldihani,Hadeel Almousa et al.
Aymen Alqurain et al.
BackgroundHypertension remains a leading modifiable risk factor for cardiovascular disease, and effective anti-hypertensive prescribing is essential for optimal management. This study will evaluate the patterns of anti-hypertensive prescrip...
Comparative Effect of Ticagrelor and Clopidogrel on Left Ventricular Remodeling in Acute Coronary Syndrome Patients: A Retrospective Cohort Study [0.03%]
替格瑞洛和氯吡格雷对急性冠脉综合征患者左心室重塑影响的比较：一项回顾性队列研究
Fawaz H Tawhari,Mohammad F Zaitoun,Ehab Elmongui et al.
Fawaz H Tawhari et al.
BackgroundAcute coronary syndrome (ACS) remains a leading cause of mortality globally. Dual antiplatelet therapy (DAPT) is standard after percutaneous coronary intervention (PCI). While ticagrelor has demonstrated favorable myocardial effec...
Factors Associated With Loop Diuretic De-escalation in Patients With Acute Decompensated Heart Failure: The Influence of Guideline Directed Medical Therapy Initiation [0.03%]
急性心力衰竭脱水治疗中指南推荐药物使用对利尿剂减停因素的影响研究
Satoshi Hanazawa,Noriko Kohyama,Erika Iwasaki et al.
Satoshi Hanazawa et al.
BackgroundIn patients with heart failure (HF), loop diuretics (LD) are recommended to relieve congestion and may be de-escalated if symptoms improve. However, long-term use of the same LD dose is sometimes required owing to potential conges...
Preliminary Evidence for the Association of APOB rs1042034 With Short-Term Statin-Induced Lipid Lowering: An Exploratory Study in Vietnam [0.03%]
初步探讨APOB基因多态性与中国南方汉族人短期他汀类药物降脂反应关系的研究
Chau Thi Kim Doan,Anh Tan To Le,Chieu Thi Truong et al.
Chau Thi Kim Doan et al.
ObjectivesTo characterize the rs1042034 allele distribution in Vietnamese adults with untreated hypercholesterolemia and evaluate its impact on baseline lipid profiles and the early lipid-lowering response to rosuvastatin 20 mg.Materials an...
Eleutheroside E Attenuates Doxorubicin-Induced Cardiotoxicity by Suppressing Ferroptosis Through Activation of the Nrf2/SLC7A11/GPX4 Signaling Pathway [0.03%]
eleutheroside E通过激活Nrf2/SLC7A11/GPX4信号通路抑制铁死亡从而缓解阿霉素引起的心脏毒性
Peng Sun,Liheng Chen,Xiangzhou Chen et al.
Peng Sun et al.
Doxorubicin (DOX)-induced cardiotoxicity significantly impairs cancer patient survival rates. Eleutheroside E (EE), a polyphenolic compound with established cardioprotective properties against high-altitude myocardial injury and ischemia/re...
Knockdown of CXCL13 Improves Vascular Remodeling, Reduces Blood Pressure and Protects the Heart in a Hypertensive rat Model by Regulating the PF4V1/NF-κB Signaling Pathway [0.03%]
下调CXCL13通过调节PF4V1/NF-κB信号通路改善高血压大鼠血管重构、降低血压和保护心脏功能
Jie Ma,Xiaoguang Sun,Xianjun Hu
Jie Ma
BackgroundCardiovascular disease remains the first major reason for death in global, and hypertension is one very usual risk factor for this disease. Chemokine (CXC motif) ligand 13 (CXCL13) exhibits a crucial role in the development and an...