Cytoplasmic P53 Immunostaining With N-Terminus P53 Antibody And Absence Of Staining With C-Terminus P53 Antibody: A Report Of Two Pediatric Sarcomas With Distal Truncating TP53 Mutations Affecting Nuclear Localization Domain [0.03%]
N端P53抗体的细胞质P53免疫染色及C端P53抗体缺如：2例TP53远端截短突变影响核定位域的儿童肉瘤报告
Hilda Mirbaha,Deyssy Carrillo,Midori Mitui et al.
Hilda Mirbaha et al.
P53 immunohistochemical staining with antibodies targeted to epitopes at or near the N-terminus are commonly used in diagnostic pathology practice as a surrogate for TP53 mutations. The abnormal staining patterns indicating TP53 mutations i...
Expression of SATB2 in Neuroendocrine Carcinomas of the Lung: Frequent Immunopositivity of Large Cell Neuroendocrine Carcinoma with a Diagnostic Pitfall [0.03%]
SATB2在肺神经内分泌癌中的表达：大细胞神经内分泌癌常见免疫阳性及其诊断陷阱
Hiromichi Inoue,Jun Matsushima,Satoru Kobayashi et al.
Hiromichi Inoue et al.
Small cell lung carcinoma (SCLC) and pulmonary large cell neuroendocrine carcinoma (LCNEC) are both classified as lung neuroendocrine carcinoma (NEC). It has recently been reported that the special AT-rich sequence-binding protein 2 (STAB2)...
A Rare Case of Low-Grade Dedifferentiated Liposarcoma Presenting as a Pharyngeal Polyp: Avoiding a Pitfall With Significant Repercussions [0.03%]
低度恶变脂肪肉瘤致咽部息肉样突起一例报告：避免误诊以减少严重后果
Natalia Georgantzoglou,Donald Green,Joel A Lefferts et al.
Natalia Georgantzoglou et al.
Dedifferentiated liposarcoma is a nonlipogenic sarcoma of variable histological grade that frequently arises in association with a well-differentiated liposarcoma. Dedifferentiation occurs in approximately 10% of well-differentiated liposar...
Pulmonary Hypertensive Changes Secondary to COVID-19 Pneumonia in a Chronically SARS-CoV-2-Infected Bilateral Lung Explant [0.03%]
慢性SARS-CoV-2感染的双侧肺移植标本中继发于COVID-19肺炎的肺动脉高压改变
Joseph M Rohr,Heather Strah,David Berkheim et al.
Joseph M Rohr et al.
COVID-19, the syndrome caused by the novel coronavirus SARS-CoV-2, has spread throughout the world, causing the death of at least three million people. For the over 81 million who have recovered, however, the long-term effects are only begi...
Primary Sclerosing Epithelioid Fibrosarcoma of the Kidney: A Case Report and Review of the Literature [0.03%]
原发性硬化上皮样纤维肉瘤肾脏癌的病例报告及文献回顾
Yan Peng,Tongbing Chen,Dachuan Zhang et al.
Yan Peng et al.
Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma. We report one case of primary kidney SEF occurring in a 38-year-old man. Microscopically, epithelioid neoplastic cells are mainly arranged in cords and nests embed...
A Case Report of Mucoepidermoid Carcinoma With Extensive Keratinization in Parotid: Expanding the Morphologic Spectrum [0.03%]
广泛的角化型腮腺黏液表皮样癌一例报告及文献复习——形态学谱系的扩展
Mei Kong,Bo Wang,Xiaoxi Wang et al.
Mei Kong et al.
Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of salivary glands in children and young adults. Typically, it is composed of squamoid, mucin-producing and intermediate-types cells. However, overt keratinization is rare. T...
Squamous Differentiation in the Thyroid: Metaplasia, Neoplasia, or Bystander? [0.03%]
甲状腺鳞状分化：变异、新生物还是伴随病变？
Meagan A Chambers,Peter M Sadow,Darcy A Kerr
Meagan A Chambers
Background. Squamous differentiation within the thyroid is seen in a variety of settings. Squamous epithelium is non-native to the thyroid, and its debated origins span reactive metaplasia and developmental/embryologic remnants. Despite a l...
Clinical Characteristics, Pathology and Outcome of 237 Patients With Synovial Sarcoma: Single Center Experience [0.03%]
滑膜肉瘤的临床特点、病理及预后：单中心报道237例患者的经验
Hao Cheng,Chi Yihebali,Hongtu Zhang et al.
Hao Cheng et al.
Background. Synovial sarcoma (SS) is a rare soft tissue sarcoma. Available data regarding survival outcomes of patients with SS still remains limited. In this study, a single center retrospective analysis was performed to investigate the cl...
Endometrial Stromal Expression of ER, PR, and B-Catenin Toward Differentiating Hyperplasia Diagnoses [0.03%]
子宫内膜基质的ER、PR和B-连环蛋白表达用于鉴别增生性疾病诊断
Paschalis Chatzipantelis,Michail Koukourakis,Konstantina Balaska et al.
Paschalis Chatzipantelis et al.
Background. The interpretation of histopathological changes of endometrial hyperplasia with or without atypia can be challenging. We aim to investigate the role of specific immunohistochemical markers in the endometrial stroma to classify e...
Periductal Stromal Tumor of the Breast: One Institution's Review of 6 Tumors Over a 22 Year Period With Immunohistochemical Analysis [0.03%]
乳腺 peri ductal间质瘤：一项为期22年的六肿瘤机构回顾及免疫组织化学分析
Longmei Zhao,Miglena K Komforti,Andrea Dawson et al.
Longmei Zhao et al.
Introduction. Periductal stromal tumor (PST) of the breast is a rare fibroepithelial neoplasm with controversial pathogenesis. Methods. A retrospective search of our Pathology database from 2000 to 2021 identified 6 PST, all evaluated accor...