High-grade Transformation in Adult Granulosa Cell Tumor: Potential Diagnostic Challenges and the Utility of Molecular Testing [0.03%]
成人颗粒细胞瘤的高级别转化：潜在的诊断挑战及分子检测的应用价值
Aysha Mubeen,Ian Martin,Deepti Dhall
Aysha Mubeen
Adult granulosa cell tumor (AGCT) is the most common sex cord-stromal tumor, accounting for about 1% of all ovarian tumors. It has a propensity for recurrences, especially late in the disease course. High-grade or sarcomatoid transformation...
Primary Intranodal Epithelioid Hemangioendothelioma with Molecular Confirmation [0.03%]
原发性淋巴结上皮样血管内皮细胞瘤伴分子学证实
Jennifer L Vazzano,Ashley Patton,Gabriel Tinoco et al.
Jennifer L Vazzano et al.
Epithelioid hemangioendothelioma (EHE) is a rare low-grade malignant vascular tumor with indolent biology, characterized by reciprocal t(1;3)(p36.6;q25) with resultant WWTR1::CAMTA1 gene fusion in the vast majority of cases, regardless of a...
Comprehensive Evaluation and Unique Morphologic Features of Nonsteroidal Anti-Inflammatory Drug (NSAID) Enteropathy in the Terminal Ileum [0.03%]
非甾体抗炎药性肠病的综合评估及其末段回肠的独特形态学特征分析
Jessica Nguyen,Sherry Lee,Guang-Yu Yang
Jessica Nguyen
Differentiating NSAID enteropathy from Crohn disease can be challenging on terminal ileum biopsy. It is important to distinguish these two entities for management. In this study, clinical, radiographic, endoscopic, and histologic features o...
Keratin 7 and ERBB2 Negative Mammary Paget Disease Without an Underlying in Situ and Invasive Carcinoma [0.03%]
无原位及浸润癌的单纯角蛋白7和ERBB2阴性乳头Paget病1例报告
Mariam Ratiani,Ayesha Farooq,Julie Jorns et al.
Mariam Ratiani et al.
We report a unique case of a post-menopausal female who presented with a lesion on the areola. A biopsy of the lesion demonstrated a pagetoid intraepithelial neoplasm suggesting a differential diagnosis of mammary Paget disease and pagetoid...
Giant Cell Tumor of Bone Versus Tenosynovial Giant Cell Tumor - Similarities and Differences [0.03%]
骨巨细胞瘤与滑膜巨细胞肿瘤的异同点分析
Luka Kropivšek,Jože Pižem,Blaž Mavčič
Luka Kropivšek
Giant cell tumor of bone (GCTB) and tenosynovial giant cell tumor (TGCT) share misleadingly similar names, soft texture and brown color macroscopically, osteoclast-like multinucleated giant cells microscopically and localisation in the musc...
A Rare Case of Tracheal Crystal-Storing Histiocytosis Associated with Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue [0.03%]
与黏膜相关淋巴组织边缘区淋巴瘤相关的气管结晶储积组织细胞病一例报告
Shoichi Kimura,Yuzo Oyama,Wang Ziyao et al.
Shoichi Kimura et al.
Crystal-storing histiocytosis (CSH) is a rare non-neoplastic histiocytic lesion with abnormal accumulation of immunoglobulin (Ig) light chain. CSH is associated with Ig overproduction by B-lymphoproliferative disorders (B-LPDs) or by persis...
Primary Pure Pancreatic -Type Acinar Cell Carcinoma of the Stomach: A Rare Entity with a Difficult Diagnosis and Review of the Literature [0.03%]
以胰腺导管腺癌为主的原发性胃腺鳞癌一例并文献复习
Gloria Paseiro-Crespo,María García-Nebreda,David Roldán Cortés et al.
Gloria Paseiro-Crespo et al.
Acinar cell carcinoma is an uncommon tumour, representing only 1% to 2% of all exocrine pancreatic tumours. Pancreatic-type acinar cell carcinoma can occur in other organs, including the stomach, but it is extraordinarily rare. We report a ...
A Clinicopathological and Molecular Analysis of Fumarate Hydratase (FH)-deficient Renal Cell Carcinomas with Heterogeneous Loss of FH Expression [0.03%]
异柠檬酸脱氢酶表达缺失的富马酸水合酶缺陷型肾细胞癌的临床病理和分子分析
William J Anderson,Harrison K Tsai,Lynette M Sholl et al.
William J Anderson et al.
Aims. Fumarate hydratase (FH)-deficient renal cell carcinoma (RCC) is a rare aggressive renal malignancy associated with hereditary leiomyomatosis and RCC syndrome (HLRCC). Tumors exhibiting heterogeneous (ie, patchy) FH loss by immunohisto...
Finn Morgan Auld,Consolato M Sergi
Finn Morgan Auld
Hepatoblastoma (HB) is the most common malignancy within the rare cohort of pediatric primary liver tumors. It may arise sporadically or in association with germline mutations in specific genetic syndromes. Histogenesis recapitulates fetal ...
Fibrin-Associated EBV-Positive Large B-Cell Lymphoma Incidentally Found Within a Multinodular Goiter [0.03%]
偶然发现于多结节性甲状腺肿内的纤维蛋白相关Epstein-Barr病毒阳性的大B细胞淋巴瘤
Jean-Louis Dargent,Sébastien Toffoli,Céline De Rop et al.
Jean-Louis Dargent et al.
Fibrin-associated diffuse large B-cell lymphoma (fibrin-associated DLBCL) is a very rare subtype of Epstein-Barr virus (EBV)-associated DLBCL that usually develops within fibrin-rich lesions such as cardiac myxoma, chronic hematoma, thrombu...