Interplay of PD-L1, FOXP3, and CD8 in the Immune Microenvironment of Penile Squamous Cell Carcinoma: Expression Profiles and Correlations [0.03%]
PD-L1、FOXP3和CD8在阴茎鳞状细胞癌免疫微环境中的互作:表达谱及关联分析
Sofia Canete-Portillo,Antonio L Cubilla,George J Netto et al.
Sofia Canete-Portillo et al.
Background: This study investigates the interplay between PD-L1, FOXP3+ regulatory T cells, and CD8+ cytotoxic T lymphocytes in penile squamous cell carcinoma (penile SCC), where understanding the tumor immune microenvironment is crucial. M...
Superficial Anaplastic Lymphoma Kinase (ALK)-Rearranged Myxoid Spindle Cell Neoplasms: A Case Report and Literature Review [0.03%]
关于ALK重排黏液样梭形细胞肿瘤的病例报告及文献复习
Claudia Grosse,Alexandra Grosse
Claudia Grosse
Anaplastic lymphoma kinase (ALK)-rearranged myxoid spindle cell tumors represent a recently recognized subgroup of kinase fusion-positive mesenchymal neoplasms. These tumors often arise in the superficial soft tissues but may occasionally b...
Head and Neck Region Nodular Fasciitis: A Clinicopathological Study of 50 Patients [0.03%]
头颈部节病样纤维组织炎的临床病理研究(50例报告)
Hania Fatima,Sahar Suleman,Syeda Maria Ahmad Zaidi et al.
Hania Fatima et al.
Nodular fasciitis is a benign, self-limiting, and rapidly proliferating fibroblastic/myofibroblastic lesion. Nodular fasciitis, in the head and neck region, in particular, poses significant diagnostic challenges due to its rapid growth and ...
Spectrum of Histopathologic Findings in Transgender Men Undergoing Gender-Affirming Gynecologic Surgery Following Preoperative Androgen Therapy: A Tertiary Care Center Study [0.03%]
男性跨性别者在接受雄激素治疗后的性别肯定妇科手术中的组织病理学表现:一家三级护理中心的研究
Neha Bakshi,Bheem Nanda,Seema Rao et al.
Neha Bakshi et al.
IntroductionTransgender men are assigned female sex at birth, but identify with a masculine gender identity, prompting them to undergo gender-affirming surgery, usually following androgen therapy, which induces changes in histology of hormo...
The Prognostic Significance of Programmed Death-Ligand 1 (PD-L1) in Skin Neoplasms: A Systematic Review and Meta-Analysis [0.03%]
皮肤肿瘤程序性死亡配体1(PD-L1)的预后价值:系统评价和 meta 分析
Alireza Abdollahi,Emad Mehrtash,Bita Jafarzadeh et al.
Alireza Abdollahi et al.
Background and AimsProgrammed death-ligand 1 (PD-L1) is an immune checkpoint molecule with proven therapeutic and prognostic implications. However, its prognostic significance in skin neoplasms remains controversial. In this study, we aimed...
Rosai-Dorfman Disease With Novel BRAF Fusion Involving the Central Nervous System [0.03%]
涉及中枢神经系统的具有新型BRAF融合的Rosai-Dorfman病
Jessica Alvarez-Lesmes,Andrew Rosenberg,Daniel P Cassidy
Jessica Alvarez-Lesmes
Rosai-Dorfman disease is an uncommon histiocytic neoplasm that is often self-limiting; however, rarely, it exhibits aggressive behavior and may undergo biological transformation to histiocytic sarcoma. Pathogenic genetic drivers of Rosai-Do...
Rasheeda Mohamedali,Aishwarya Sharma,Deepander Rathore et al.
Rasheeda Mohamedali et al.
SMARCB1/INI1 (integrase interactor 1) deficient undifferentiated carcinomas of the gastrointestinal tract are highly aggressive neoplasms with a poor clinical outcome. Due to their rarity, the clinicopathological characteristics and molecul...
The Use of Cytology Specimens in Isolation for Diagnosis of High-Grade Serous Carcinoma Prior to Initiation of Neoadjuvant Chemotherapy: A 3-Year Experience at a Large Referral Hospital [0.03%]
单用细胞学标本诊断在新辅助化疗前的高级别浆液性癌:一家大型转诊医院3年的经验
Sameer Chhetri Aryal,Natalie Banet
Sameer Chhetri Aryal
Introduction: Selected patients with pelvic high-grade serous carcinoma (HGSC) receive neoadjuvant chemotherapy prior to resection. Guidelines allow cytopathology fluids to be used to confirm this diagnosis before neoadjuvant chemotherapy, ...
Overlapping Morphologic and Immunophenotypic Features of Plasmacytoid Urothelial Carcinoma and Urothelial Carcinoma With Osteoclast-Like Giant Cells [0.03%]
浆细胞样尿路上皮癌和具有破骨样巨细胞的尿路上皮癌的重叠形态和免疫表型特征
Carol N Rizkalla,Maria Tretiakova,Sean R Williamson et al.
Carol N Rizkalla et al.
Osteoclast-rich undifferentiated carcinoma of the urinary tract, herein referred to as urothelial carcinoma with osteoclast-like giant cells (UCOGC), is an uncommon tumor currently classified under "poorly differentiated" urothelial carcino...
Succinate Dehydrogenase A-Deficient Renal Cell Carcinoma with Predominantly Papillary Structures: A Case Report and Review of the Literature [0.03%]
以乳头状结构为主的琥珀酸脱氢酶A缺陷型肾细胞癌一例报告及文献复习
Xu Liu,Jiao Liu,Jingwen Hu et al.
Xu Liu et al.
Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is a rare molecularly defined renal tumor characterized by defects in the subunit types SDHA, SDHB, SDHC, and SDHD, with most of these genetic alterations involving the SDHB...