The microtubule GTP-tubulin cap size is modulated during cell division [0.03%]
细胞分裂过程中微管GTP-微管帽大小的变化
Anna C Cassidy,Dylan T Burnette,Marija Zanic
Anna C Cassidy
Microtubule dynamics change during cell division to enable rapid microtubule network remodeling. The switching from microtubule growth to shrinkage is attributed to the loss of a stabilizing GTP-cap structure at the growing microtubule end....
Markus K Klose,Junghun Kim,Brigitte F Schmidt et al.
Markus K Klose et al.
Neuropeptide release by Drosophila sLNv clock neurons controls circadian behaviors and sleep. Strikingly, neuropeptide content in sLNv terminals is rhythmic with late-night accumulation occurring while the axon arbor is expanding in prepara...
Matrix stiffness and stress relaxation regulate osteogenesis through histone demethylases KDM4B and KDM6B [0.03%]
基质刚度和应力松弛通过组蛋白去甲基酶KDM4B和KDM6B调节成骨细胞分化
Ian M Tayler,Amy Zhu,Abhishek Sharma et al.
Ian M Tayler et al.
Stem cells sense biophysical cues within their extracellular microenvironment and respond via mechanotransduction signaling pathways that induce changes in gene expression and associated cell fate outcomes. Histone modifying enzymes are kno...
ATG9B Regulates Mitochondrial Integrity and Apoptotic Tumor Cell Death [0.03%]
ATG9B调节线粒体完整性及细胞凋亡型肿瘤细胞死亡
Hong Cao,Lixia Guo,Jing Chen et al.
Hong Cao et al.
It is well established that many tumor types possess defective autophagic pathways. Several studies have reported that the transmembrane, autophagic lipid scramblase ATG9B is altered in multiple cancers, suggesting that this dysregulation c...
Celia Municio-Diaz,Nicolas Minc
Celia Municio-Diaz
The Cell Wall (CW) protects fungal cells from various challenges making its integrity essential for cell survival. CW integrity is monitored by transmembrane sensors that activate effectors to promote CW synthesis in response to injuries. S...
Linear Z-line-like alignment of capping protein in obliquely striated muscle of the nematode C. elegans suggests that dense bodies are not equivalent to Z-lines [0.03%]
秀丽隐杆线虫斜纹肌中类似Z带的直线排列表明密体不等同于Z线
Shoichiro Ono,Emily Nickoloff-Bybel,Kennosuke Kurimaru et al.
Shoichiro Ono et al.
Many invertebrates have obliquely striated muscles, in which neighboring thin and thick filaments are staggered and aligned obliquely. This type of muscle allows force production over a wide range of lengths and is beneficial for soft-bodie...
Mitophagy Enhancement Delays Mouse Mesenchymal Stem Cell Senescence by Attenuating the Senescence-Associated Secretory Phenotype [0.03%]
线粒体自噬增强通过减弱衰老相关分泌表型延迟鼠源间充质干细胞的衰老
Yingying Sun,Xudong Fu,Yi Li et al.
Yingying Sun et al.
Aging is a complex biological process that heightens susceptibility to age-related diseases, often driven by declining mitochondrial function. Mitophagy, the selective removal of damaged mitochondria, is a key quality-control mechanism esse...
Analyses of bent spindles reveal the mechanics of anaphase B in fission yeast [0.03%]
分裂纺锤体的分析揭示了裂殖酵母后期B的动力学
Paula Real-Calderón,Thomas G Fai,Rafael R Daga et al.
Paula Real-Calderón et al.
The mitotic spindle in the fission yeast Schizosaccharomyces pombe is a single bundle of microtubules which elongates to segregate the chromosomes during anaphase B. The mechanical properties of the spindle and the forces driving its elonga...