David C Knight,Eleanor P Lewis,Kimberly H Wood
David C Knight
During Pavlovian conditioning the expression of a conditioned response typically serves as evidence that an association between a conditioned stimulus (CS) and an unconditioned stimulus (UCS) has been learned. However, learning-related chan...
Early-life maternal separation and social isolation produce an increase in impulsive action but not impulsive choice [0.03%]
早期的母体分离和社会孤立会产生冲动行为但不会产生冲动选择
Vedran Lovic,Darren Keen,Paul J Fletcher et al.
Vedran Lovic et al.
Early life environment, events, and context, such as mother-offspring relationship, can have profound effects on future behavior and physiology. We investigated the effects of long-term maternal and social separation, through artificial rea...
Tap withdrawal circuit interneurons require CREB for long-term habituation in Caenorhabditis elegans [0.03%]
CREB决定秀丽隐杆线虫中触须撤回电路中间神经元的长期习惯化现象
Tiffany A Timbers,Catharine H Rankin
Tiffany A Timbers
We investigated the role of the Caenorhabditis elegans CREB (cAMP response element binding protein) homologue, crh-1, in response to tap (nonlocalized mechanosensory stimulation) and tap habituation. Worms with a loss-of-function mutation i...
Involvement of retrosplenial cortex in forming associations between multiple sensory stimuli [0.03%]
后楔叶皮层在多重感觉刺激之间形成关联的作用
Siobhan Robinson,Christopher S Keene,Hannah F Iaccarino et al.
Siobhan Robinson et al.
The retrosplenial cortex (RSP) is highly interconnected with medial temporal lobe structures, yet relatively little is known about its specific contributions to learning and memory. One possibility is that RSP is involved in forming associa...
Orbitofrontal cortex and basolateral amygdala lesions result in suboptimal and dissociable reward choices on cue-guided effort in rats [0.03%]
眶额皮层和基底外侧杏仁核损伤导致大鼠在基于线索的精力引导下做出次优且解离化的奖励选择
Serena Ostrander,Victor A Cazares,Charissa Kim et al.
Serena Ostrander et al.
The orbitofrontal cortex (OFC) and basolateral nucleus of the amygdala (BLA) are important neural regions in responding adaptively to changes in the incentive value of reward. Recent evidence suggests these structures may be differentially ...
Comparative Study
Behavioral neuroscience. 2011 Jun;125(3):350-9. DOI:10.1037/a0023574 2011
Yogita Chudasama
Yogita Chudasama
Executive function allows us to interact with the world in a purposive, goal-directed manner. It relies on several cognitive control operations that are mediated by different regions of the prefrontal cortex. While much of our knowledge abo...
Introduction to the special section on "translational models of prefrontal cortical function" [0.03%]
额叶功能的转化模型介绍
Mark G Baxter
Mark G Baxter
Impaired functioning of the prefrontal cortex is particularly prominent in many forms of psychopathology and in degenerative brain diseases. Because it is challenging to draw causal links between specific brain abnormalities and impaired co...
The role of context in re-acquisition of extinguished alcoholic beer-seeking [0.03%]
上下文在消退的酒精性啤酒寻求行为重新获得中的作用
Andrea L Willcocks,Gavan P McNally
Andrea L Willcocks
We studied the role of context in reacquisition of extinguished reward-seeking. Rats were trained to respond for alcoholic beer, then extinguished and retrained. Reacquisition was faster than acquisition regardless of whether retraining occ...
Glossopharyngeal nerve transection impairs unconditioned avoidance of diverse bitter stimuli in rats [0.03%]
迷走神经切断影响大鼠对多种苦味刺激的非条件性回避反应
Laura C Geran,Susan P Travers
Laura C Geran
There is growing evidence of heterogeneity among responses to bitter stimuli at the peripheral, central and behavioral levels. For instance, the glossopharyngeal (GL) nerve and neurons receiving its projections are more responsive to bitter...
The risky business of dopamine agonists in Parkinson disease and impulse control disorders [0.03%]
多巴胺激动剂与帕金森病及冲动控制障碍的利弊分析
Daniel O Claassen,Wery P M van den Wildenberg,K Richard Ridderinkhof et al.
Daniel O Claassen et al.
Risk-taking behavior is characterized by pursuit of reward in spite of potential negative consequences. Dopamine neurotransmission along the mesocorticolimbic pathway is a potential modulator of risk behavior. In patients with Parkinson's d...