Sex differences in behavior and glutamic acid decarboxylase in Long Evans rats after prolonged social isolation beginning in adolescence [0.03%]
青春期开始长期的社会孤立对长-evans大鼠行为及谷氨酸脱羧酶的性别差异的影响
Shannon M Harding,Aaron R Van Dyke,Matthew Little et al.
Shannon M Harding et al.
Social isolation can have long-term effects on brain development and behavior and increases the risk of developing clinical conditions, including anxiety disorders. One modulator of the stress response is gamma-aminobutyric acid, an inhibit...
Mike E Le Pelley,Poppy Watson,Reinout W Wiers
Mike E Le Pelley
Before we can make any choice, we must gather information from the environment about what our options are. This information-gathering process is critically mediated by attention, and our attention is, in turn, shaped by our previous experie...
Bilal A Bari,Samuel J Gershman
Bilal A Bari
Psychopathology is vast and diverse. Across distinct disease states, individuals exhibit symptoms that appear counter to the standard view of rationality (expected utility maximization). We argue that some aspects of psychopathology can be ...
Hannah L Schoenberg,Samantha K Moriarty,Neil E Winterbauer et al.
Hannah L Schoenberg et al.
Pavlovian extinction reduces the performance of conditioned responses and occurs when the conditioned stimulus (CS) is repeatedly presented in the absence of the unconditioned stimulus (US). However, when the CS is experienced in a context ...
Leveraging individual differences in cue-reward learning to investigate the psychological and neural basis of shared psychiatric symptomatology: The sign-tracker/goal-tracker model [0.03%]
利用线索-奖赏学习的个体差异来探讨共享精神病症状的心理和神经基础：信号追踪者/目标追踪者模型
Princess C Felix,Shelly B Flagel
Princess C Felix
In our modern environment, we are bombarded with stimuli or cues that exert significant influence over our actions. The extent to which such cues attain control over or disrupt goal-directed behavior is dependent on several factors, includi...
Brain electrical patterns associated with pleasure and emotion induced by tonal and atonal music [0.03%]
与由旋律音乐和无调性音乐引起的情绪及快乐相关的脑电波模式
Pablo Valdés-Alemán,Bernarda Téllez-Alanís,Adriana Zamudio-Gurrola
Pablo Valdés-Alemán
Several studies in the last 40 years have used electroencephalography (EEG) to recognize patterns of brain electrical activity correlated with emotions evoked by various stimuli. For example, the frontal alpha and theta asymmetry models to ...
Lrp8 knockout mice fed a selenium-replete diet display subtle deficits in their spatial learning and memory function [0.03%]
饲喂充足硒饮食的Lrp8敲除小鼠出现空间学习和记忆功能轻度缺陷
Odette Leiter,David Brici,Imesh Aththanayake Mudiyan et al.
Odette Leiter et al.
Selenium is an essential trace element that is delivered to the brain by the selenium transport protein selenoprotein P (SEPP1), primarily by binding to its receptor low-density lipoprotein receptor-related protein 8 (LRP8), also known as a...
Indirect and direct cannabinoid agonists differentially affect mesolimbic dopamine release and related behaviors [0.03%]
间接和直接的大麻素激动剂对中脑边缘多巴胺释放及相关行为的不同影响
Kevin M Honeywell,Timothy G Freels,Megan A McWain et al.
Kevin M Honeywell et al.
The cannabinoid system is being researched as a potential pharmaceutical target for a multitude of disorders. The present study examined the effect of indirect and direct cannabinoid agonists on mesolimbic dopamine release and related behav...
Less is more: Smaller hippocampal subfield volumes predict greater improvements in posttraumatic stress disorder symptoms over 2 years [0.03%]
越小越好：海马亚区体积较小预示 PTSD 症状在两年内改善更显著
Joseph DeGutis,Danielle R Sullivan,Sam Agnoli et al.
Joseph DeGutis et al.
Posttraumatic stress disorder (PTSD) is a heterogeneous disorder, and symptom severity varies over time. Neurobiological factors that predict PTSD symptoms and their chronicity remain unclear. This study investigated whether the volume of t...
Hannah R Stutt,Matthew A Weber,Rachel C Cole et al.
Hannah R Stutt et al.
Rodent behavioral studies have largely focused on male animals, which has limited the generalizability and conclusions of neuroscience research. Working with humans and rodents, we studied sex effects during interval timing that requires pa...