Recent Progress in Microenvironment-Responsive Nanodrug Delivery Systems for the Targeted Treatment of Rheumatoid Arthritis [0.03%]
近年环境响应型纳米药物递送系统在类风湿性关节炎靶向治疗中的研究进展
Shuhang Liu,Ming Yang,Han Liu et al.
Shuhang Liu et al.
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that often causes joint pain, swelling, and functional impairments. Drug therapy is the main strategy used to alleviate the symptoms of RA; however, drug therapy may hav...
Dana Wegierak,Pinunta Nittayacharn,Michaela B Cooley et al.
Dana Wegierak et al.
Contrast-enhanced ultrasound is currently used worldwide with clinical indications in cardiology and radiology, and it continues to evolve and develop through innovative technological advancements. Clinically utilized contrast agents for ul...
Nanoparticles Bounded to Interfering RNAs as a Therapy for Pancreatic Cancer: A Systematic Review [0.03%]
纳米颗粒结合干扰RNA治疗胰腺癌的系统性研究回顾
Patricia Lara,Francisco Quiñonero,Raul Ortiz et al.
Patricia Lara et al.
Pancreatic cancer is one of the tumors with poor prognosis and low survival due to late diagnosis, high resistance, and very limited effective therapeutic options. Thus, new pharmacological treatments are necessary to improve the prognosis ...
Engineered Macrophage Exosomes Deliver Drug-Targeted Therapy for Breast Cancer [0.03%]
工程化巨噬细胞外泌体递送药物靶向治疗乳腺癌
Mingrui Feng,Lifang Zhang,Zhuoling Zou et al.
Mingrui Feng et al.
Breast cancer is a highly widespread form of malignant tumor characterized by a high rate of recurrence and mortality; it primarily occurs when tumor cells spread to peripheral regions of the body. Macrophages have a significant impact on t...
Development of Self-Adjuvants in mRNA Vaccine and Its Application in Disease Prevention and Treatment [0.03%]
基于mRNA疫苗自佐剂的开发及其在疾病预防和治疗中的应用研究进展
Huaibin Yu,Yafang Lu,Zhuorong Miao et al.
Huaibin Yu et al.
Adjuvants augment the immunogenicity of vaccines when co-administered with messenger RNA (mRNA) antigens. In recent years, nanotechnology and nanoscience have seen significant growth, resulting in the discovery of synthetic small molecule c...
Biomaterial-Mediated Metabolic Regulation of Ferroptosis for Cancer Immunotherapy [0.03%]
用于癌症免疫治疗的生物材料介导铁死亡代谢调控
Yingqi Liu,Dan Tao,Menghuan Li et al.
Yingqi Liu et al.
Ferroptosis is a lipid peroxidation-driven cell death route and has attracted enormous interest for cancer therapy. Distinct from other forms of regulated cell death, its process is involved with multiple metabolic pathways including lipids...
Fuat Topuz,Tamer Uyar
Fuat Topuz
Cyclodextrins (CDs) belong to a class of cyclic oligosaccharides characterized by their toroidal shape consisting of glucose units linked via α-1,4-glycosidic bonds. This distinctive toroidal shape exhibits a dual nature, comprising a hydr...
Nanotechnology for Targeted Inflammatory Bowel Disease Therapy: Challenges and Opportunities [0.03%]
针对炎症性肠病的纳米技术治疗：挑战与机遇
Meng-Tzu Weng,Chia-Yueh Hsiung,Shu-Chen Wei et al.
Meng-Tzu Weng et al.
Inflammatory bowel disease (IBD) is a complex and recurring inflammatory disorder that affects the gastrointestinal tract and is influenced by genetic predisposition, immune dysregulation, the gut microbiota, and environmental factors. Adva...
Unveiling Invisible Extracellular Vesicles: Cutting-Edge Technologies for Their in Vivo Visualization [0.03%]
揭秘隐形的细胞外囊泡：其体内可视化的新技术
Prakash Gangadaran,Fatima Khan,Ramya Lakshmi Rajendran et al.
Prakash Gangadaran et al.
Extracellular vesicles (EVs), nanosized lipid bilayer vesicles released by nearly all types of cells, play pivotal roles as intercellular signaling mediators with diverse biological activities. Their adaptability has attracted interest in e...
Recent Progress on Nanomedicine-Mediated Repolarization of Tumor-Associated Macrophages for Cancer Immunotherapy [0.03%]
近期基于纳米药物介导的肿瘤相关巨噬细胞重编程的癌症免疫治疗研究进展
Jing-Yang Zhang,Yun-He Su,Xu Wang et al.
Jing-Yang Zhang et al.
Tumor-associated macrophages (TAMs) constitute the largest number of immune cells in the tumor microenvironment (TME). They play an essential role in promoting tumor progression and metastasis, which makes them a potential therapeutic targe...