Jiangwei Zhou,Yongcheng Zhang,Fushi Dong et al.
Jiangwei Zhou et al.
Radiotherapy (RT) is one of the cornerstones in cancer treatment, with approximately 50% of patients receiving radiation regimens annually. However, its clinical efficacy is constrained by two persistent challenges: tumor radioresistance an...
Galleria mellonella as a Simple Yet Reliable In Vivo Model for Nanotoxicology: Techniques and Applications [0.03%]
纳米毒理学的在 vivo 模型：技术与应用
Núria Blanco-Cabra,Joana Admella,Eduard Torrents
Núria Blanco-Cabra
Nanomaterials are a rapidly advancing tool with applications across various scientific fields. However, their interactions with living organisms have raised numerous safety concerns, making it crucial to develop reliable models to predict a...
Sex and Gender Dimensions in Hazard and Risk Assessment of Engineered Nanomaterials [0.03%]
纳米材料风险评估中的性别差异研究进展与未来方向
Lucija Božičević,Karolina Jagiello,Anita Sosnowska et al.
Lucija Božičević et al.
The knowledge on hazards and risks connected to human exposure to engineered nanomaterials (ENMs) is still very limited, despite several decades of research and regulatory efforts at the international level. In particular, sex/gender-relate...
Emerging Biomimetic Drug Delivery Nanoparticles Inspired by Extracellular Vesicles [0.03%]
受外泌体启发的仿生药物递送纳米粒子研究进展
Viswanathan Sundaram,Santosh Aryal
Viswanathan Sundaram
Nanoparticles (NPs) made up of cellular components such as extracellular vesicles (EVs) with a biomimetic outlook have emerged as a revolutionary approach in nanomedicine, providing significant benefits for targeted drug administration, imm...
Transforming Cancer Nanotechnology Data Analysis and User Experience. Part II: Providing Future Solutions Using Large Language Models [0.03%]
癌症纳米技术数据分析和用户体验转型。第二部分：使用大型语言模型提供未来解决方案
Weina Ke,Rui He,Mark A Jensen et al.
Weina Ke et al.
The advances in cancer nanotechnologies and current efforts focused on data sharing, along with the associated challenges, have been summarized in the first part of this review. Herein, we explore the potential of Large Language Models (LLM...
Engineered Extracellular Vesicles in Arthritic Diseases: Therapeutic Applications & Challenges [0.03%]
工程化细胞外囊泡在关节炎性疾病中的治疗应用及挑战
Seif Ehab,Ola A Gaser,Atif Abdulwahab A Oyouni et al.
Seif Ehab et al.
Arthritic diseases are a significant global health challenge, highlighting the urgent need for innovative therapeutic strategies. Extracellular vesicles (EVs) have emerged as promising candidates for treating various intractable diseases. T...
Transforming Cancer Nanotechnology Data Analysis and User Experience. Part I: Current Challenges and Solutions Provided by caNanoLab [0.03%]
癌症纳米技术数据分析和用户体验转型 第一部分 当前的挑战及caNanoLab提供的解决方案
Weina Ke,Rui He,Mark A Jensen et al.
Weina Ke et al.
Cancer nanotechnologies have the potential to revolutionize cancer diagnosis and treatment; however, their complexity poses challenges to data analysis and knowledge sharing. caNanoLab, a dedicated cancer nanotechnology data-sharing portal,...
Wei-Chun Chou,Alexa Canchola,Fan Zhang et al.
Wei-Chun Chou et al.
Nanomedicine harnesses nanoscale materials, such as lipid, polymeric, and inorganic nanoparticles, to deliver diagnostic or therapeutic agents for cancer, infectious disease, and neurological disorders, among others. However, translating pr...
Qian Wang,Shuxin Lyu,Xiaoyu Zhang et al.
Qian Wang et al.
Photoacoustic imaging (PAI), an intriguing imaging technology, is increasingly being utilized in both basic and clinical medical research. PAI in the second near-infrared window (NIR-II) offers a series of notable advantages, enhanced depth...
Recent Advances in Prodrug-Loaded Nanoparticles for Enhanced Immunotherapy Efficacy [0.03%]
用于增强免疫治疗效果的前药负载型纳米颗粒最新进展
Yajun Xu,Jincheng Du,Ya Liu et al.
Yajun Xu et al.
Immunotherapy has emerged as an important approach for cancer treatment. However, most drugs for activating the cancer-immunity cycle have serious side effects from systemic off-target action, endangering patients' safety. Prodrug-loaded na...