Hui Wang,Yiyun Cheng
Hui Wang
mRNA delivery has emerged as a transformative approach in biotechnology and medicine, offering a versatile platform for the development of novel therapeutics. Unlike traditional small molecule drugs or protein-based biologics, mRNA therapeu...
Strategies in Electrospun Polymer and Hybrid Scaffolds for Enhanced Cell Integration and Vascularization for Bone Tissue Engineering and Organoids [0.03%]
用于骨组织工程和类器官的电纺聚合物和杂化支架中增强细胞整合和血管化的策略
Martyna Polak,Joanna Ewa Karbowniczek,Urszula Stachewicz
Martyna Polak
Addressing the demand for bone substitutes, tissue engineering responds to the high prevalence of orthopedic surgeries worldwide and the limitations of conventional tissue reconstruction techniques. Materials, cells, and growth factors cons...
Nanotechnology-Enabled Targeted Protein Degradation for Cancer Therapeutics [0.03%]
基于纳米技术的癌症治疗蛋白降解疗法
Wutong Zhao,Yongbin Jiang,Xiufen Li et al.
Wutong Zhao et al.
Targeted protein degradation (TPD) represents an innovative therapeutic strategy that has garnered considerable attention from both academic and industrial sectors due to its promising developmental prospects. Approximately 85% of human pro...
Nanomaterials for the Diagnosis and Treatment of Triple-Negative Breast Cancer [0.03%]
用于三阴性乳腺癌诊断和治疗的纳米材料
Xuan Sun,Dandan Li,Yue Lv et al.
Xuan Sun et al.
In recent years, the diagnosis and treatment at the early stages significantly raise the survival rate of breast cancer patients. Moreover, antibody drugs pave the way toward precision target therapy. However, the treatment and survival of ...
Advanced Antibacterial Strategies for Combatting Biomaterial-Associated Infections: A Comprehensive Review [0.03%]
应对生物材料相关感染的先进抗菌策略综述
Esra Kasapgil,Manuela Garay-Sarmiento,César Rodriguez-Emmenegger
Esra Kasapgil
Biomaterial-associated infections (BAIs) pose significant challenges in modern medical technologies, being a major postoperative complication and leading cause of implant failure. These infections significantly risk patient health, resultin...
Dynamic Real-Time Biosensing Enabled Biorhythm Tracking for Psychiatric Disorders [0.03%]
实时生物传感驱动的精神疾病生物节律追踪方法研究
Karin Huizer,Ivneet Kaur Banga,Ruchita Mahesh Kumar et al.
Karin Huizer et al.
This review article explores the transformative potential of dynamic, real-time biosensing in biorhythm tracking for psychiatric disorders. Psychiatric diseases, characterized by a complex, heterogeneous, and multifactorial pathophysiology,...
Hypocrellin: A Natural Photosensitizer and Nano-Formulation for Enhanced Molecular Targeting of PDT of Melanoma [0.03%]
光敏剂原毛酸及纳米制剂在增强黑色素瘤分子靶向光动力治疗中的应用
Precious Winterrose Gugu Nkosi,Rahul Chandran,Heidi Abrahamse
Precious Winterrose Gugu Nkosi
Nano-formulation has generated attention in the battle against cancer, because of its great flexibility, reduced adverse side effects, and accuracy in delivering drugs to target tissues dependent on the size and surface characteristics of t...
Challenges in Exploiting Human H Ferritin Nanoparticles for Drug Delivery: Navigating Physiological Constraints [0.03%]
人源H型铁蛋白纳米颗粒药物递送的挑战：克服生理约束
Alberto Macone,Chiara Cappelletti,Alessio Incocciati et al.
Alberto Macone et al.
Over the past two decades, ferritin has emerged as a promising nanoparticle for drug delivery, catalyzing the development of numerous prototypes capable of encapsulating a wide array of therapeutic agents. These ferritin-based nanoparticles...
Electrochemical Nanosensor-Based Emerging Point-Of-Care Tools: Progress and Prospects [0.03%]
电化学生物纳米传感器的新兴床边工具：进展和前景
Jaqueline Pena-Zacarias,Md Ikhtiar Zahid,Md Nurunnabi
Jaqueline Pena-Zacarias
Early detection of disease remains a crucial challenge in medicine. Delayed diagnosis often leads to limited treatment options, increased disease progression, and unfortunately, even death in some cases. To address this, the need for rapid,...
Better, Faster, Stronger: Accelerating mRNA-Based Immunotherapies With Nanocarriers [0.03%]
更快、更好、更强：利用纳米载体加速基于mRNA的免疫疗法
Henrique M B Carvalho,Tiago A S Fidalgo,Rita C Acúrcio et al.
Henrique M B Carvalho et al.
Messenger ribonucleic acid (mRNA) therapeutics are attracting attention as promising tools in cancer immunotherapy due to their ability to leverage the in vivo expression of all known protein sequences. Even small amounts of mRNA can have a...