Advances in Peptide-Based Cancer Vaccines: Materials, Targeting, and Delivery Strategies [0.03%]
基于肽的癌症疫苗进展：材料、靶向和递送策略
Shea Garland,Jacques Lux
Shea Garland
Immunotherapy, particularly immune checkpoint inhibitors (ICIs), has transformed cancer treatment by achieving durable responses in a subset of patients. However, the effectiveness of ICIs is often limited by factors such as low tumor expre...
Latest Advancements in Electrochemical Genosensors Integrated With Nanoparticles for the Detection of Nucleic Acids [0.03%]
纳米颗粒集成的电化学生物传感器最新研究进展及其用于核酸检测方面的能力
Gulsah Congur
Gulsah Congur
Biosensors are the prototypes of future miniaturized and handheld devices that can quantitatively detect the analyte with reliable results. Electrochemical biosensors are a class of biosensors that are capable of both sensitive and selectiv...
Peptide Hydrogels for Postoperative Tumor Therapy: Enhancing Immune Modulation and Local Drug Delivery [0.03%]
用于术后肿瘤治疗的肽水凝胶：增强免疫调节和局部药物递送
Sangshuang Li,Huaimin Wang
Sangshuang Li
Postoperative tumor cavities provide a transient but targetable immune niche where local biomaterials can suppress residual disease and complement systemic therapy. Self-assembling peptidic hydrogels are uniquely suited for this setting bec...
Emerging Advances in Nanomedicine for Targeted Cancer Photoimmunotherapy and Photo-Immunometabolic Therapy [0.03%]
纳米医学在癌症光免疫治疗及光免疫代谢治疗领域的新进展
Alexander Chota,Paromita Sarbadhikary,Heidi Abrahamse et al.
Alexander Chota et al.
Immunotherapy has advanced quickly as a promising new approach for cancer treatment, but its therapeutic efficacy and clinical translation have lagged expectations, because of its inability to directly target tumors, low response rates, and...
Harnessing the Power of D-Alpha-Tocopheryl Polyethylene Glycol Succinate-Based Nanoparticles for Targeted Breast Cancer Therapy [0.03%]
利用D-α-生育酚聚乙二醇琥珀酸基纳米颗粒进行靶向乳腺癌治疗
Zrien Naz,Mohammad Fareed,Niher Tabassum Snigdha et al.
Zrien Naz et al.
Breast cancer (BC) continues to be the most common cancer affecting women globally, posing significant therapeutic challenges due to limited therapeutic efficacy, non-specific drug targeting, systemic toxicity, and the emergence of chemores...
Design, Synthesis and Biomedical Applications of 18F Nanoprobes: A Comprehensive Review [0.03%]
氟-18纳米探针的设计、合成及生物医药应用综述研究
Chuqiang Que,Ying Han,Shiyao Fu et al.
Chuqiang Que et al.
18F-labeled nanoprobes represent a significant advancement in molecular imaging, integrating the high sensitivity and quantitative capabilities of positron emission tomography (PET) with the versatility of nanotechnology. This review provid...
Next-Generation Polymeric mRNA Nanocarriers: From Chemical Engineering to Organ-Selective Gene Delivery [0.03%]
下一代聚合mRNA纳米载体：从化学工程到器官选择性基因传递
Wang Chen,Dandan Zhu,Meiwan Chen et al.
Wang Chen et al.
mRNA-based therapeutics as an emerging biotherapeutic platform offers immense potential in various fields, including vaccine development, tumor immunology, protein replacement therapy, and gene editing. However, critical bottlenecks persist...
Chronic Respiratory Diseases: Use of Quantum Particles as Nanotheranostic Agents [0.03%]
慢性呼吸系统疾病：作为纳米治疗诊断剂的量子粒子的应用
Neelam,Shefali Mallik,K M Neethu et al.
Neelam et al.
Chronic respiratory diseases are among the top five non-communicable diseases (NCDs) contributing to the highest global mortality and morbidity. These diseases, which include chronic obstructive pulmonary disease (COPD), asthma, diffuse par...
Rational Design of Zwitterionic Nanosystems to Overcome Biological Barriers for Drug Delivery by Various Administration Routes [0.03%]
用于各种给药途径克服生理屏障的两性离子纳米递送系统的设计
Jiahui Ma,Dongyue Ding,Rui Xu et al.
Jiahui Ma et al.
The drug delivery nanosystems (DDNS) have demonstrated excellent potential in numerous drug modifications reliant on the physical and chemical properties. However, the main challenge in the clinical application transformation of DDNS lies i...
Jiangwei Zhou,Yongcheng Zhang,Fushi Dong et al.
Jiangwei Zhou et al.
Radiotherapy (RT) is one of the cornerstones in cancer treatment, with approximately 50% of patients receiving radiation regimens annually. However, its clinical efficacy is constrained by two persistent challenges: tumor radioresistance an...