A Two-Component Assay for Hypoxia Incorporating Long-Term Nitroreduction and Short-Term DNA-Damage Allows Differentiation of the Three Hypoxia Sub-types [0.03%]
一种两部分缺氧分析方法结合长期硝基还原和短期DNA损伤，可区分三种缺氧亚型
Cameron J Koch
Cameron J Koch
Hypoxia in tumors has many well-characterized effects that are known to prevent optimal cancer treatment. Despite the existence of a large number of assays that have supported hypoxia as an important diagnostic, there is no routine clinical...
Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays [0.03%]
帕瑞肽1基因剔除小鼠遭受中剂量γ射线照射的基因表达研究
M A Suresh Kumar,Evagelia C Laiakis,Shanaz A Ghandhi et al.
M A Suresh Kumar et al.
There is a current interest in the development of biodosimetric methods for rapidly assessing radiation exposure in the wake of a large-scale radiological event. This work was initially focused on determining the exposure dose to an individ...
Acute Effect of Low-Dose Space Radiation on Mouse Retina and Retinal Endothelial Cells [0.03%]
低剂量太空辐射对小鼠视网膜及视网膜内皮细胞的急性影响
X W Mao,M Boerma,D Rodriguez et al.
X W Mao et al.
There is concern that degradation of vision as a result of space flight may compromise both mission goals and long-term quality of life after space travel. The visual disturbances may be due to a combination of intracerebral pressure change...
Cortical Thinning and Structural Bone Changes in Non-Human Primates after Single-Fraction Whole-Chest Irradiation [0.03%]
单次全胸照射后非人灵长类动物的皮质骨变薄和结构骨变化
Michael Farris,Emory R McTyre,Catherine Okoukoni et al.
Michael Farris et al.
Stereotactic body radiation therapy (SBRT) is associated with an increased risk of vertebral compression fracture. While bone is typically considered radiation resistant, fractures frequently occur within the first year of SBRT. The goal of...
2017 Michael Fry Award Lecture When DNA is Actually Not a Target: Radiation Epigenetics as a Tool to Understand and Control Cellular Response to Ionizing Radiation [0.03%]
2017迈克尔·弗莱奖演讲当DNA并非靶点时：辐射诱导入组学作为研究和控制电离辐射的细胞反应的方法
Igor Koturbash
Igor Koturbash
Aside from the generally accepted potential to cause DNA damage, it is becoming increasingly recognized that ionizing radiation has the capability to target the cellular epigenome. Epigenetics unifies the chemical marks and molecules that c...
New Radiation Dosimetry Estimates for [18F]FLT based on Voxelized Phantoms [0.03%]
基于体素化模型的[18F]FLT放射剂量学评估的新方法
B M Mendes,A V Ferreira,L T C Nascimento et al.
B M Mendes et al.
3'-Deoxy-3-[18F]fluorothymidine, or [18F]FLT, is a positron emission tomography (PET) tracer used in clinical studies for noninvasive assessment of proliferation activity in several types of cancer. Although the use of this PET tracer is ex...
Improving Research in Radiation Oncology through Interdisciplinary Collaboration [0.03%]
通过跨学科合作推动放射肿瘤学研究的发展
Jay W Burmeister,Monica W Tracey,Sara E Kacin et al.
Jay W Burmeister et al.
The contribution of radiation oncology to the future of cancer treatment depends significantly on our continued clinical progress and future research advancements. Such progress relies on multidisciplinary collaboration among radiation onco...
Comments on "Modeling Cell Survival after Photon Irradiation Based on Double-Strand Break Clustering in Megabase Pair Chromatin Loops" by Thomas Friedrich, Marco Durante and Michael Scholz (Radiat Res 2012; 178:385-94) [0.03%]
福里德里希等人关于“基于光子照射下百万碱基对染色体环中的DNA双链断裂聚集的细胞生存模型”的述评（《辐射研究》2012年第178期385-94页）
Giovanni Borasi
Giovanni Borasi
Comments on 'Comments on "Modeling Cell Survival after Photon Irradiation Based on Double-Strand Break Clustering in Megabase Pair Chromatin Loops" by Thomas Friedrich, Marco Durante and Michael Scholz (Radiat Res 2012; 178:385-94)' [0.03%]
对Friedrich等人关于光子照射后基于Mbp染色体环DNA双链断裂聚集的细胞存活模型的评论的评述
Thomas Friedrich,Marco Durante,Michel Scholz
Thomas Friedrich
Scintillation Yield Estimates of Colloidal Cerium-Doped LaF3 Nanoparticles and Potential for "Deep PDT" [0.03%]
纳米颗粒的闪烁产额估计及在"深部PDT"中的潜在应用
Konstantin A Kudinov,Daniel R Cooper,Jonathan K Ha et al.
Konstantin A Kudinov et al.
A hybrid of radiotherapy and photodynamic therapy (PDT) has been proposed in previously reported studies. This approach utilizes scintillating nanoparticles to transfer energy to attached photosensitizers, thus generating singlet oxygen for...