Jose Alonso,Eleanor Blakely,Joseph Castro et al.
Jose Alonso et al.
A Chromosome 6, not Natural Killer Cell, Contribution to Radiation- and Bleomycin-Induced Lung Disease in Mice [0.03%]
小鼠放射和博来霉素致肺病的易感性与第六号染色体有关，而与自然杀伤细胞无关
Anne-Marie Lemay,Christina K Haston
Anne-Marie Lemay
Inbred strains of mice differ in susceptibility to both radiation-induced and bleomycin-induced pulmonary fibrosis and these traits have been mapped to a common locus on chromosome 6 which harbors genes of natural killer cell function. To i...
In Vitro Radiobiological Advantages of Hypofractionation Compared with Conventional Fractionation: Early-Passage NSCLC Cells are Less Aggressive after Hypofractionation [0.03%]
与常规分割相比，低分割的放射生物学优势：早期传代非小细胞肺癌(NSCLC)细胞在低分割后活性较低
Haibo Zhang,Chao Wan,Jing Huang et al.
Haibo Zhang et al.
Hypofractionated radiotherapy is a new and highly effective mode of radiation therapy. For this study we used biologically equivalent dose (BED), the dose required to give the same log cell kill as the schedule being studied. BED has been w...
Comparative Study
Radiation research. 2018 Dec;190(6):584-595. DOI:10.1667/RR14951.1 2018
Dicentric Dose Estimates for Patients Undergoing Radiotherapy in the RTGene Study to Assess Blood Dosimetric Models and the New Bayesian Method for Gradient Exposure [0.03%]
RTGene研究中接受放射治疗的患者的dicentric剂量估算，用于评估血液剂量学模型和新的梯度曝光贝叶斯方法
Jayne Moquet,Manuel Higueras,Ellen Donovan et al.
Jayne Moquet et al.
The RTGene study was focused on the development and validation of new transcriptional biomarkers for prediction of individual radiotherapy patient responses to ionizing radiation. In parallel, for validation purposes, this study incorporate...
Involvement of the Hypothalamic Glutamatergic System in the Development of Radiation-Induced Pica in Rats [0.03%]
下丘脑谷氨酸能系统在辐射诱导的大鼠泥食症发病机制中的作用研究
Kouichi Yamamoto,Atsushi Yamatodani
Kouichi Yamamoto
Since the peripheral serotoninergic pathway is involved in the development of radiation-induced nausea and vomiting, referred to as radiation sickness, serotonin 5-HT3 receptor antagonists are used as a preventive measure, although patients...
Nonhuman Primates with Acute Radiation Syndrome: Results from a Global Serum Metabolomics Study after 7.2 Gy Total-Body Irradiation [0.03%]
接受7.2Gy全身照射的非人灵长类动物急性辐射综合症的血清代谢组学研究结果
Evan L Pannkuk,Evagelia C Laiakis,Melissa Garcia et al.
Evan L Pannkuk et al.
Threats of nuclear terrorism coupled with potential unintentional ionizing radiation exposures have necessitated the need for large-scale response efforts of such events, including high-throughput biodosimetry for medical triage. Global met...
Challenges and Benefits of Repurposing Products for Use during a Radiation Public Health Emergency: Lessons Learned from Biological Threats and other Disease Treatments [0.03%]
化学生物恐怖事件中的放射性公共卫生紧急情况的产品再利用的挑战与效益及其它疾病的治疗措施所获得的启示和教训
Andrea L DiCarlo,David R Cassatt,William E Dowling et al.
Andrea L DiCarlo et al.
The risk of a radiological or nuclear public health emergency is a major growing concern of the U.S. government. To address a potential incident and ensure that the government is prepared to respond to any subsequent civilian or military ca...
Computational Modeling and Clonogenic Assay for Radioenhancement of Gold Nanoparticles Using 3D Live Cell Images [0.03%]
基于三维活细胞图像的金纳米粒子放效增强的计算模型及集落形成实验研究
Wonmo Sung,Yoon Jeong,Hyejin Kim et al.
Wonmo Sung et al.
Radioenhancement of gold nanoparticles (GNPs) has shown great potential for increasing the therapeutic efficiency of radiotherapy. Here we report on a computational model of radiation response, which was developed to predict the survival cu...
Differential Radiation Sensitivity in p53 Wild-Type and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy [0.03%]
与衰老而非凋亡或非保护自噬有关的p53野生型和p53缺陷型肿瘤细胞的放射敏感性差异
Jingwen Xu,Nipa H Patel,Tareq Saleh et al.
Jingwen Xu et al.
Studies of radiation interaction with tumor cells often focus on apoptosis as an end point; however, clinically relevant doses of radiation also promote autophagy and senescence. Moreover, functional p53 has frequently been implicated in co...
Accelerator-Based Tests of Shielding Effectiveness of Different Materials and Multilayers using High-Energy Light and Heavy Ions [0.03%]
基于加速器的轻离子和重离子高能量束流对不同材料及多层组合屏蔽效果的测试研究
Martina Giraudo,Christoph Schuy,Uli Weber et al.
Martina Giraudo et al.
The roadmap for space exploration foresees longer journeys and further excursions outside low-Earth orbit as well as the establishment of permanent outposts on other celestial bodies, such as the Moon or Mars. The design of spacecrafts and ...