Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer [0.03%]
增强的药理学抗坏血酸氧化放射增敏胰腺癌
Matthew S Alexander,Brianne R O&#x;Leary,Justin G Wilkes et al.
Matthew S Alexander et al.
Pharmacologic ascorbate (P-AscH-) is emerging as a promising adjuvant for advanced pancreatic cancer. P-AscH- generates hydrogen peroxide (H2O2), leading to selective cancer cell cytotoxicity. Catalytic manganoporphyrins, such as MnT4MPyP, ...
Early Diffusion-Weighted Imaging and Proton Magnetic Resonance Spectroscopy Features of Liver Transplanted Tumors Treated with Radiation in Rabbits: Correlation with Histopathology [0.03%]
兔移植瘤放疗早期扩散加权成像和氢磁共振波谱特征：与病理组织学的相关性研究
Yueming Li,Dandan Lin,Youliang Weng et al.
Yueming Li et al.
In this study, we sought to determine how diffusion-weighted imaging (DWI) and proton magnetic resonance spectroscopy (1H-MRS) features are associated with histopathological results, and explored the cellular mechanisms of DWI and 1H-MRS in...
Joy Garrett,Carol H Sampson,P Artur Plett et al.
Joy Garrett et al.
Several investigators performing bone marrow transplantation studies have previously reported sporadic increases in mortality that were associated with pronounced swelling in the face, head and neck of mice. Over the past few years, we and ...
Comprehensive Review of Quality of Publications and Meta-analysis of Genetic Damage in Mammalian Cells Exposed to Non-Ionizing Radiofrequency Fields [0.03%]
关于非离子射频场暴露哺乳动物细胞遗传损伤的发表质量和系统评价及meta分析综述
Vijayalaxmi,Thomas J Prihoda
Vijayalaxmi
There have been numerous published studies reporting on the extent of genetic damage observed in animal and human cells exposed in vitro and in vivo to non-ionizing radiofrequency fields (RF, electromagnetic waves that carry energy as they ...
Performance of Fluorescent Cell-Labeling Dyes under Simulated Europa Mission Radiation Doses [0.03%]
类欧罗巴辐射条件下荧光细胞标记染料的性能研究
Iulia Hanczarek,Aaron J Kenna,Chris Lindensmith et al.
Iulia Hanczarek et al.
We investigated the performance of several commonly used fluorescent dyes after exposure to a simulated Europa mission total ionizing radiation dose of 300 krad (3 kGy) applied using a 60Co source. Dyes irradiated in aqueous solution or as ...
Age Dependence of Radiation-Induced Genomic Instability in Mouse Hematopoietic Stem Cells [0.03%]
小鼠造血干细胞辐射诱导的基因组不稳定性的年龄依赖性研究
Kentaro Ariyoshi,Tomisato Miura,Kosuke Kasai et al.
Kentaro Ariyoshi et al.
Age at exposure is a critical factor that influences the risk of radiation-induced leukemia. Accumulating evidence suggests that ionizing radiation can induce genomic instability and promote leukemogenesis in hematopoietic stem cells (HSCs)...
Effects of Low-to-Moderate Doses of Gamma Radiation on Mouse Hematopoietic System [0.03%]
低中剂量γ射线辐射对小鼠造血系统的影响
XiangHong Li,Wanchang Cui,Lisa Hull et al.
XiangHong Li et al.
In this study, we investigated the effects of low-to-moderate doses of radiation in mice, given our limited understanding of the health risks associated with these exposures. Here, we demonstrate the different responses of the CD2F1 mouse h...
Challenges and Benefits of Repurposing Licensed/Approved/Cleared Products for a Radiation Indication [0.03%]
已获许可/批准/认可产品用于辐射指示的再定位所面临的挑战和好处
Paul W Price,Andrea L DiCarlo
Paul W Price
Increasingly, the risk of a radiological or nuclear public health emergency is a major concern for the U.S. government. To address a potential incident and ensure that the U.S. Government is prepared to respond to any civilian or military c...
Radiation-Drug Combinations to Improve Clinical Outcomes and Reduce Normal Tissue Toxicities: Current Challenges and New Approaches: Report of the Symposium Held at the 63rd Annual Meeting of the Radiation Research Society, 15-18 October 2017; Cancun, Mexico [0.03%]
提高临床疗效和降低正常组织毒性的放疗-药物联合：当前的挑战与新的策略——国际辐射研究学会第63届年会专题研讨会报告（墨西哥坎昆，2017年10月15日至18日）
Kelly C Falls,Ricky A Sharma,Yaacov R Lawrence et al.
Kelly C Falls et al.
The National Cancer Institute's (NCI) Radiation Research Program (RRP) is endeavoring to increase the relevance of preclinical research to improve outcomes of radiation therapy for cancer patients. These efforts include conducting symposia,...