Association with Polyamines and Polypeptides Increases the Relative Yield of 2-Deoxyribonolactone Lesions in Radiation-Damaged DNA [0.03%]
与多胺和多肽的相互作用增加放射线损伤DNA中2-脱氧 ribono lactone类损伤的比例
Yuriy Razskazovskiy,Modeste Tegomoh,Marina Roginskaya
Yuriy Razskazovskiy
The production of 2-deoxyribonolactones (C1'-oxidation product), C4'-oxidized abasic sites and C5'-carbonyl terminated strand scission products was investigated in complexes of double-stranded DNA with protamine, poly-L-lysine and spermine ...
RITCARD: Radiation-Induced Tracks, Chromosome Aberrations, Repair and Damage [0.03%]
辐射诱导痕迹、染色体异常、修复与损伤模型(RITCARD)
Ianik Plante,Artem Ponomarev,Zarana Patel et al.
Ianik Plante et al.
Chromosome aberrations (CAs) are one of the effects of radiation exposure and can have implications for human health in the space environment, since they are related to cancer risk. In radiation research, chromosome aberrations are a conven...
Integration of Neurons Derived from Transplanted BDNF-Overexpressing Neural Stem Cells into Circuit of the Irradiated Hippocampus [0.03%]
载有BDNF基因过表达的神经干细胞移植的放射损伤海马组织中的细胞整合研究
Qixian Zhang,Xue Zhong,Jie Zhang et al.
Qixian Zhang et al.
Stem cell transplantation is thought to be an effective method for radiation-induced cognitive dysfunction. However, there have been few studies performed to determine whether transplanted stem cells can integrate into hippocampus circuits....
RABiT-II-DCA: A Fully-automated Dicentric Chromosome Assay in Multiwell Plates [0.03%]
RABiT-II-DCA：微孔板中完全自动化的易位多中心染色体分析法
Ekaterina Royba,Mikhail Repin,Sergey Pampou et al.
Ekaterina Royba et al.
We developed a fully-automated dicentric chromosome assay (DCA) in multiwell plates. All operations, from sample loading to chromosome scoring, are performed, without human intervention, by the second-generation Rapid Automated Biodosimetry...
Radioresistance of Serpinb3a-/- Mice and Derived Hematopoietic and Marrow Stromal Cell Lines [0.03%]
Serpinb3a基因敲除小鼠及由此衍生的造血细胞和骨髓基质细胞系的辐射抵抗性研究
Stephanie Thermozier,Xichen Zhang,Wen Hou et al.
Stephanie Thermozier et al.
Serpins are a group of serine-proteases involved in multiple signal transduction pathways in mammalian cells. In particular, Serpinb3a is involved in the lysosomal necrosis cell death pathway with components that overlap with radiation-indu...
Radiation and Risk of Liver, Biliary Tract, and Pancreatic Cancers among Atomic Bomb Survivors in Hiroshima and Nagasaki: 1958-2009 [0.03%]
广岛和长崎原子弹幸存者肝、胆道及胰腺癌发病风险的流行病学研究（1958～2009年）
Atsuko Sadakane,Benjamin French,Alina V Brenner et al.
Atsuko Sadakane et al.
The Life Span Study (LSS) of atomic bomb survivors has consistently demonstrated significant excess radiation-related risks of liver cancer since the first cancer incidence report. Here, we present updated information on radiation risks of ...
Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice [0.03%]
血管内皮细胞放射敏感性增加促进小鼠肠道晚期损伤发生发展
Chang-Lung Lee,Andrea R Daniel,Matt Holbrook et al.
Chang-Lung Lee et al.
Exposure of the gastrointestinal (GI) tract to ionizing radiation can cause acute and delayed injury. However, critical cellular targets that regulate the development of radiation-induced GI injury remain incompletely understood. Here, we i...
Radia Tamarat,Marc Benderitter
Radia Tamarat
Single-Step Synthesis of Atmospheric CO2 Sorbents through Radiation-Induced Graft Polymerization on Commercial-Grade Fabrics [0.03%]
通过辐射诱导接枝聚合在商用织物上一步法合成大气CO2吸附剂
Eli Fastow,Sean Cook,Pablo Dean et al.
Eli Fastow et al.
Primary amines form a key component of a well-studied mechanism for capturing carbon dioxide (CO2) from the atmosphere. This study comprises a single-step synthesis of a novel sorbent for CO2 by grafting monomers rich in primary amines to t...
DNA Damage Processing is Perturbed in Both Proliferative and Non-Proliferative Cells of Increased Chronological Cellular Age [0.03%]
增龄细胞无论在增殖或非增殖状态下其 DNA 损伤处理过程均受到干扰
Rebecca Sabin,Gaia Pucci,Rhona M Anderson
Rebecca Sabin
p53BP1 forms discrete foci within minutes of radiation exposure, at sites of DNA double-strand breaks, which ordinarily decay to background levels within 24 h of induction. Longer lived, persisting 53BP1 foci are thought to mark unrepaired ...