Impact of Single Dose Photons and Carbon Ions on Perfusion and Vascular Permeability: A Dynamic Contrast-Enhanced MRI Pilot Study in the Anaplastic Rat Prostate Tumor R3327-AT1 [0.03%]
单次剂量光子和碳离子对灌注和血管通透性的影响：在大鼠前列腺癌R3327-AT1模型中动态对比增强MRI的初步研究
Alina L Bendinger,Lisa Seyler,Maria Saager et al.
Alina L Bendinger et al.
We collected initial quantitative information on the effects of high-dose carbon (12C) ions compared to photons on vascular damage in anaplastic rat prostate tumors, with the goal of elucidating differences in response to high-LET radiation...
Monitoring Physiological Changes in Neutron-Exposed Normal Mouse Brain Using FDG-PET and DW-MRI [0.03%]
利用FDG-PET和DW-MRI监测正常小鼠脑部 neutron照射后的生理变化
Kyung Jun Kang,Ki-Hye Jung,Eun-Ji Choi et al.
Kyung Jun Kang et al.
We monitored a physiological response in a neutron-exposed normal mouse brain using two imaging tools, [18F]fluro-deoxy-D-glucose positron emission tomography ([18F]FDG-PET) and diffusion weighted-magnetic resonance imaging (DW-MRI), as an ...
Natalia Louneva,Amit Maity,Ann R Kennedy
Natalia Louneva
D-dimer plasma levels were evaluated to determine whether they are altered by radiation. D-dimer levels were measured in radiation oncology patients, who were diagnosed with prostate, breast or lung cancer, or leukemia, as well as in health...
Comprehensive Analysis of the Kinetics of Radiation-Induced Lymphocyte Loss in Patients Treated with External Beam Radiation Therapy [0.03%]
外照射放射治疗患者辐射诱导淋巴细胞减少动力学的全面分析
Susannah G Ellsworth,Anirudh Yalamanchali,Hong Zhang et al.
Susannah G Ellsworth et al.
Radiation-induced lymphopenia (RIL) is associated with worse survival in patients with solid tumors, as well as lower response rates to checkpoint inhibitors. While single-fraction total-body irradiation is known to result in exponential de...
Differentiation of Heterogeneous Radiation Exposure Using Hematology and Blood Chemistry [0.03%]
利用血液学和血浆生化指标鉴别异质性辐照小鼠模型
M Waleed Gaber,Shaefali P Rodgers,Tien T Tang et al.
M Waleed Gaber et al.
In the aftermath of a nuclear incident, survivors will suffer the deleterious effects from acute radiation exposure. The majority of those affected would have received heterogeneous radiation exposure, reflected in hematological metrics and...
Sex-Specific Effects of a Wartime-Like Radiation Exposure on Cognitive Function [0.03%]
wartime-like辐射暴露的认知功能的性别差异效应
Al Anoud D Baddour,Lauren A Apodaca,Leila Alikhani et al.
Al Anoud D Baddour et al.
Evaluating the risk for central nervous system (CNS) effects after whole-body or partial-body irradiation presents challenges due in part to the varied exposure scenarios in the context of occupational, accidental or wartime releases. Risk ...
The Importance and Clinical Implications of FLASH Ultra-High Dose-Rate Studies for Proton and Heavy Ion Radiotherapy [0.03%]
FLASH超高速剂量放射治疗的重要性和临床意义——质子及重离子放疗的研究进展
Nicholas W Colangelo,Edouard I Azzam
Nicholas W Colangelo
The goal of radiation therapy is to provide the highest probability of tumor control while minimizing normal tissue toxicity. Recently, it has been discovered that ultra-high dose rates of ionizing radiation may preferentially spare normal ...
Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats [0.03%]
富氢水对放射线导致的认知功能障碍的影响实验研究
Mengya Liu,Hui Yuan,Jingjing Yin et al.
Mengya Liu et al.
The goal of this work was to determine whether hydrogen-rich water (HRW) could attenuate radiation-induced cognitive dysfunction in rats and to explore the underlying mechanisms. Rats received 30 Gy whole-brain irradiation using a 6-MeV ele...
Comparison of Proteomic Biodosimetry Biomarkers Across Five Different Murine Strains [0.03%]
五种不同小鼠品系的蛋白质组 biodosimetry 生物标志物比较
Mary Sproull,Uma Shankavaram,Kevin Camphausen
Mary Sproull
In the event of a radiological or nuclear attack, advanced clinical countermeasures are needed for screening and medical management of the exposed population. Such a population will represent diverse heterogeneity in physiological response ...
Comparative Study
Radiation research. 2019 Dec;192(6):640-648. DOI:10.1667/RR15442.1 2019