Generation of a Transcriptional Radiation Exposure Signature in Human Blood Using Long-Read Nanopore Sequencing [0.03%]
基于纳米孔长读段测序技术的人类血液辐射暴露转录特征图谱绘制研究
Lourdes Cruz-Garcia,Grainne OBrien,Botond Sipos et al.
Lourdes Cruz-Garcia et al.
In the event of a large-scale event leading to acute ionizing radiation exposure, high-throughput methods would be required to assess individual dose estimates for triage purposes. Blood-based gene expression is a broad source of biomarkers...
Response to the Letter to the Editor, 'Comments on "Improved Modeling of Plutonium-DTPA Decorporation," (Radiat Res 2019; 191:201-10) by Gremy and Miccoli' [0.03%]
关于Gremy和Miccoli的评论信“关于‘改良Pu-DTPA清吸模型’(Radiat Res 2019; 191:201-10)”的回复
Sara Dumit,Bastian Breustedt,Maia Avtandilashvili et al.
Sara Dumit et al.
Comment
Radiation research. 2019 Dec;192(6):682-683. DOI: 2019
Prediction of Cell Survival after Exposure to Mixed Radiation Fields with the Local Effect Model [0.03%]
使用局部效应模型预测混合辐射场作用下的细胞存活率
Tabea Pfuhl,Thomas Friedrich,Michael Scholz
Tabea Pfuhl
Mixed radiation fields comprise the most common form of radiation exposure. Given their relevance in radiation protection, cancer radiotherapy and space research, accurate predictions of the corresponding radiation effects are essential. Th...
Enhancement of Cytotoxicity of Enediyne Compounds by Hyperthermia: Effects of Various Metal Complexes on Tumor Cells [0.03%]
金属化合物增敏enediyne抗肿瘤活性的研究
Joy E Garrett,Erin Metzger,Katelyn Schmitt et al.
Joy E Garrett et al.
Enediyne natural products are a class of compounds that were recognized for their potential as chemotherapeutic agents many years ago, but found to be highly cytotoxic due to their propensity for low thermal activation. Bergman cyclization ...
Effect of Heterogeneity in Background Incidence on Inference about the Solid-Cancer Radiation Dose Response in Atomic Bomb Survivors by Cologne et al., Radiat Res 2019; 192:388-398 [0.03%]
Cologne等关于原子 bomb 受害者中固体癌放射反应的剂量效应受背景发病异质性影响的分析,Radiat Res 2019;192:388-398
Linda Walsh,Uwe Schneider
Linda Walsh
Comparison of Radiation Dose Reconstruction Methods to Investigate Late Adverse Effects of Radiotherapy for Childhood Cancer: A Report from the Childhood Cancer Survivor Study [0.03%]
儿童癌症幸存者研究中关于放射治疗晚期不良作用的辐射剂量重建方法比较研究报告
Sara J Schonfeld,Rebecca M Howell,Susan A Smith et al.
Sara J Schonfeld et al.
Quantification of radiation dose to normal tissue during radiotherapy is critical for assessing risk for radiotherapy-related late effects, including subsequent neoplasms (SNs). Case-control studies of SNs typically reconstruct absorbed rad...
Comparative Study
Radiation research. 2020 Feb;193(2):95-106. DOI:10.1667/RR15308.1
Effects of Brain Irradiation in Immune-Competent and Immune-Compromised Mouse Models [0.03%]
免疫健全和免疫缺陷型小鼠脑部放射效应的差异性研究
Mohammad Saki,Kruttika Bhat,Sirajbir S Sodhi et al.
Mohammad Saki et al.
Patient-derived orthotopic xenografts (PDOXs) closely recapitulate primary human glioblastoma (GBM) tumors in terms of histology and genotype. Compared to other mouse strains, NOD-scid IL2Rgammanull (NSG) mice show excellent tumor take rate...
UVC-Emitting LuPO4:Pr3+ Nanoparticles Decrease Radiation Resistance of Hypoxic Cancer Cells [0.03%]
缺氧癌细胞辐射抵抗力下降:LuPO4:Pr3+纳米颗粒发出的UVC的作用
Matthias Müller,Sara Espinoza,Thomas Jüstel et al.
Matthias Müller et al.
Radiation-resistant hypoxic tumor areas continue to present a major limitation for successful tumor treatment. To overcome this radiation resistance, an oxygen-independent treatment is proposed using UVC-emitting LuPO4:Pr3+ nanoparticles (N...
Impact of the PrC-210 Radioprotector Molecule on Cancer Deaths in p53-Deficient Mice [0.03%]
化合物PrC-210放射保护剂对p53基因缺陷小鼠癌症死亡率的影响
William E Fahl,Frank Jermusek,Thomas Guerin et al.
William E Fahl et al.
Radiation-induced cancer is an ongoing and significant problem, with sources that include clinics worldwide in which 3.1 billion radiology exams are performed each year, as well as a variety of other scenarios such as space travel and nucle...
Role of Endoplasmic Reticulum and Mitochondrion in Proton Microbeam Radiation-Induced Bystander Effect [0.03%]
内质网和线粒体在质子微束辐照旁效应中的作用
Chen Dong,Wenzhi Tu,Mingyuan He et al.
Chen Dong et al.
It is well known that mitochondria and the endoplasmic reticulum (ER) play important roles in radiation response, but their functions in radiation-induced bystander effect (RIBE) are largely unclear. In this study, we found that when a smal...