MicroRNA Profile of Exosomes and Parental Cells is Differently Affected by Ionizing Radiation [0.03%]
离子辐射对细胞及细胞外囊泡微小核糖核酸谱型的影响不同
Agata Abramowicz,Wojciech Łabaj,Justyna Mika et al.
Agata Abramowicz et al.
Exosomes are key mediators of cell-to-cell communication involved in different aspects of the response to ionizing radiation. The functional role of exosomes depends on their molecular cargo, including protein and miRNA content. In this wor...
Peter M Corry,Robert J Griffin
Peter M Corry
Flow Cytometry Definition of Rat Mammary Epithelial Cell Populations and Their Distinct Radiation Responses [0.03%]
.flow cytometry定义的大鼠乳腺上皮细胞群及其不同的辐射反应
Ken-Ichi Kudo,Masaru Takabatake,Kento Nagata et al.
Ken-Ichi Kudo et al.
Breast tissue is very susceptible to radiation-induced carcinogenesis, and mammary stem/progenitor cells are potentially important targets of this. The mammary epithelium is maintained as two mostly independent lineages of luminal and basal...
Identifying Circulating and Lung Tissue Cytokines Associated with Thoracic Irradiation and AEOL 10150 Treatment in a Nonhuman Primate Model [0.03%]
一种非人灵长类模型中与胸部放射和AEOL 10150治疗相关的循环细胞因子及肺组织细胞因子的鉴定
Wanchang Cui,Kim G Hankey,Pei Zhang et al.
Wanchang Cui et al.
Inflammatory cytokines have been suggested to play important roles in radiation-induced lung injury (RILI). Identifying significantly changed circulating and tissue cytokines after thoracic irradiation will aid in deciphering the mechanism ...
Effects of Low-Dose Gamma-Ray Radiation on Apoptosis and Development of Zebrafish Embryo Brain [0.03%]
低剂量γ射线辐射对斑马鱼胚胎脑发育及细胞凋亡的影响
Weichao Zhao,Penghui Yuan,Nan Hu et al.
Weichao Zhao et al.
To investigate the effects of low-dose γ irradiation on apoptosis and development of the brain in zebrafish embryos, cumulative 15 mGy doses of γ rays from a 137Cs source were used to irradiate zebrafish embryos at 2 h post-fertilization ...
Effects of Hypoxia and Radiation-Induced Exosomes on Migration of Lung Cancer Cells and Angiogenesis of Umbilical Vein Endothelial Cells [0.03%]
缺氧及放射诱导的肺癌细胞外泌体对血管生成的影响研究
Fang Mo,Yanwu Xu,Junling Zhang et al.
Fang Mo et al.
Numerous studies have shown that exosomes play important roles in tumor biology development. However, the function of exosomal protein in cancer progression under different oxygen condition after irradiation is poorly understood. In this st...
Radiation-Induced Bystander Effect can be Transmitted Through Exosomes Using miRNAs as Effector Molecules [0.03%]
辐射诱导的旁观者效应可以通过外泌体使用miRNA作为效应分子进行传递
Yu Du,Shufang Du,Liu Liu et al.
Yu Du et al.
The radiation-induced bystander effect (RIBE) is a destructive reaction in nonirradiated cells and is one primary factor in determining the efficacy and success of radiation therapy in the field of cancer treatment. Previously reported stud...
Fruit Fly, Drosophila melanogaster, as an In Vivo Tool to Study the Biological Effects of Proton Irradiation [0.03%]
利用果蝇(Drosophila melanogaster)活体模型研究质子辐射的生物学效应
Koichiro Nakajima,TianXiang Gao,Kazuhiko Kume et al.
Koichiro Nakajima et al.
The clinical superiority of proton therapy over photon therapy has recently gained recognition; however, the biological effects of proton therapy remain poorly understood. The lack of in vivo evidence is especially important. Therefore, the...
Assessing Nonlinearity in Harderian Gland Tumor Induction Using Three Combined HZE-irradiated Mouse Datasets [0.03%]
利用三种结合的高 LET 粒子照射数据评估硬腺肿瘤诱导的非线性效应
Lori J Chappell,S Robin Elgart,Caitlin M Milder et al.
Lori J Chappell et al.
Recently reported studies considering nonlinearity in the effects of low-dose space radiation have assumed a nontargeted mechanism. To date, few analyses have been performed to assess whether a nontargeted term is supported by the available...
The Intestinal Microbiota Plays as a Protective Regulator Against Radiation Pneumonitis [0.03%]
肠道微生物群作为辐射性肺炎的保护调节者发挥作用
Xiaoqi Nie,Long Li,Minxiao Yi et al.
Xiaoqi Nie et al.
Radiation pneumonitis is a common complication of thoracic irradiation for lung cancer patients. The healthy gut microbiota plays an important role in the local mucosal defense process as well as pulmonary immunomodulation of the host. Howe...