TSPAN8-mediated Epithelial-mesenchymal Transition Drives Acquired Radioresistance in Cervical Cancer [0.03%]
TSPAN8介导的上皮间质转化诱导宫颈癌获得性放射抵抗性
Jing-Nan Wang,Ling-Li Liao,Fan Yang et al.
Jing-Nan Wang et al.
Acquired radioresistance remains a major obstacle to effective radiotherapy for cervical cancer, often driven by epithelial-mesenchymal transition (EMT). This study reveals TSPAN8 as a novel regulator of EMT-mediated radioresistance, offeri...
Hypersaline Inhalation: an Alternative to Pulmonary Lavages for Removing Inhaled insoluble Radioactive Particles? [0.03%]
超咸吸入:去除吸入的难溶性放射性颗粒的肺灌洗替代方法?
Hubert Peiffer,Olivier Grémy,Anne Van der Meeren
Hubert Peiffer
The medical management of victims after pulmonary intake of radioactive insoluble particles is a real challenge. The recommended treatment in case of plutonium or cobalt intake is the administration of the chelating agent DTPA, which remain...
National Institute of Allergy and Infectious Diseases (NIAID) - Bundeswehr Institute of Radiobiology (BIR) Joint Programmatic Workshop on a Global Approach to Medical Countermeasure Development in Radiological Public Health Preparedness [0.03%]
美国国家过敏症和传染病研究所(NAIID)与德国联邦国防军放射生物学研究所(BIR)关于公共卫生辐射应急准备医疗应对措施全球性方法的联合研讨会
Merriline M Satyamitra,Michael Abend,Christina Beinke et al.
Merriline M Satyamitra et al.
This invited commentary grew out of a presentation made at the 2025 ConRad Meeting in Munich, Germany, and summarizes talks made by researchers supported by the National Institute of Allergy and Infectious Diseases (NIAID) and the Bundesweh...
Application of Blood Smears for the Identification of Non-exposed Individuals after a Nuclear Incident [0.03%]
核事故后利用血涂片鉴别未受照个体的应用研究
Prabal Subedi,Lukas Duchrow,Anne Dietz et al.
Prabal Subedi et al.
Healthcare systems will be overwhelmed in the case of a large-scale nuclear incident, not only by members of the exposed population, but also by non-exposed ("worried-well") individuals. Current methods of biodosimetry are time-consuming an...
Lt Colonel Mc Pd Dr Stefan Eder
Lt Colonel Mc Pd Dr Stefan Eder
Comparative Analysis of Proton and Carbon-Ion Therapy for Head and Neck Cancer: LET-Dependent α/β Ratios in EQD2 and NTCP [0.03%]
质子和碳离子治疗头颈部肿瘤的比较分析:LET依赖性α/β比值在EQD2和NTCP中的作用
Yushi Wakisaka,Yuya Miyasaka,Yuki Tominaga et al.
Yushi Wakisaka et al.
Proton therapy (PT) and carbon-ion therapy (CIT) differ not only in their physical dose characteristics but also in their biological effects, attributable to variations in fractionation protocols and linear energy transfer (LET). These diff...
Interlaboratory Comparison of the Dicentric Chromosome Assay for a Mixed Gamma-Neutron Radiation Field [0.03%]
混合γ中子辐射场的dicentric染色体检测法实验室比对研究
Jakub Vavra,Daniela Ekendahl,Lukas Kotik et al.
Jakub Vavra et al.
In the event of a criticality accident, there is a risk of high-dose exposure for affected individuals from a mixed gamma-neutron radiation field. Dosimetry in such cases is complex and requires multiple approaches. Biodosimetry methods, es...
Lipophagy Mitigates Radiation-induced Liver Lipid Disorders and Damage in Adolescent Mice [0.03%]
自噬作用缓解小鼠放射性肝脂质紊乱和损伤事件选中的句子
Yu Feng Zhang,Yu Xu,Ke Zhou et al.
Yu Feng Zhang et al.
Ionizing radiation poses a significant health risk to adolescent livers by disrupting lipid metabolism, yet protective mechanisms remain poorly understood. We investigated this using a pubertal mouse model exposed to localized X-irradiation...
Case Report: The Limited Value of Dicentric Analysis in Cases of Suspected Overexposure to a Low X-ray Dose [0.03%]
个例报告:低剂量X射线疑似过度暴露的 dicentric 检测有限价值分析
Christina Beinke,Elizabeth A Ainsbury,Andreas Lamkowski et al.
Christina Beinke et al.
Dicentric analysis is used to confirm ionizing radiation exposure and to estimate individual absorbed doses. However, assessing doses below 100 mSv and clearly communicating the findings to the affected person is challenging, partly due to ...
Repurposing Quetiapine as an Adjuvant Therapeutic Agent for Triple-Negative Breast Cancer [0.03%]
喹硫平在治疗三阴性乳腺癌中的再利用研究
Ling He,Purva Joshi,Angeliki Ioannidis et al.
Ling He et al.
Triple-negative breast cancer (TNBC) lacks actionable molecular targets, so treatment primarily relies on cytotoxic chemotherapy and radiotherapy, yet relapse, resistance, and metastasis still drives poor long-term survival. Dopamine signal...