Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion [0.03%]
评估血管辐射防护剂对辐射诱导的血管通透性和白细胞黏附影响的新型小鼠耳静脉模型的应用
Kathleen A Ashcraft,Kingshuk Roy Choudhury,Sam R Birer et al.
Kathleen A Ashcraft et al.
Vascular injury after radiation exposure contributes to multiple types of tissue injury through a cascade of events. Some of the earliest consequences of radiation damage include increased vascular permeability and promotion of inflammation...
Jaimee C Eckers,Adam D Swick,Randall J Kimple
Jaimee C Eckers
Dose-Modifying Factor of Radiation Therapy with Concurrent Cisplatin Treatment in HPV-Positive Squamous Cell Carcinoma: A Preclinical Study [0.03%]
HPV阳性鳞状细胞癌同期放化疗患者顺铂剂量调整的放射增敏因素：一项基于动物模型的研究
Ajda Prevc,Simona Kranjc,Maja Cemazar et al.
Ajda Prevc et al.
Human papillomavirus (HPV) is an important etiological factor in oropharyngeal squamous cell carcinoma (SCC). Compared to HPV-negative tumors, HPV-positive oropharyngeal SCC has shown a better response to nonsurgical treatments. In this stu...
NASA GeneLab Project: Bridging Space Radiation Omics with Ground Studies [0.03%]
NASA基因实验室项目：连接空间辐射组学与地面研究
Afshin Beheshti,Jack Miller,Yared Kidane et al.
Afshin Beheshti et al.
Accurate assessment of risks of long-term space missions is critical for human space exploration. It is essential to have a detailed understanding of the biological effects on humans living and working in deep space. Ionizing radiation from...
Circulating Cytokine/Chemokine Concentrations Respond to Ionizing Radiation Doses but not Radiation Dose Rates: Granulocyte-Colony Stimulating Factor and Interleukin-18 [0.03%]
离子辐射剂量而非剂量率会影响循环细胞因子和趋化因子浓度：粒细胞集落刺激因子和白介素-18
Juliann G Kiang,Joan T Smith,Sara R Hegge et al.
Juliann G Kiang et al.
Exposure to ionizing radiation is a crucial life-threatening factor in nuclear and radiological incidents. It is known that ionizing radiation affects cytokine/chemokine concentrations in the blood of B6D2F1 mice. It is not clear whether ra...
Mice Lacking RIP3 Kinase are not Protected from Acute Radiation Syndrome [0.03%]
不含RIP3激酶的小鼠不能够免受急性辐射综合征的影响
Katherine D Castle,Andrea R Daniel,Everett J Moding et al.
Katherine D Castle et al.
Exposure to high doses of ionizing radiation can cause lethal injury to normal tissue, thus inducing acute radiation syndrome. Acute radiation syndrome is caused by depletion of bone marrow cells (hematopoietic syndrome) and irreparable dam...
DNA Topoisomerase IB as a Potential Ionizing Radiation Exposure and Dose Biomarker [0.03%]
拓扑异构酶IB作为潜在的电离辐射暴露与剂量生物标志物研究进展
Rotem Daudee,Rafi Gonen,Uzi German et al.
Rotem Daudee et al.
In radiation exposure scenarios where physical dosimetry is absent or inefficient, dose estimation must rely on biological markers. A reliable biomarker is of utmost importance in correlating biological system changes with radiation exposur...
Analysis of Radiation-Induced Chromosomal Aberrations on a Cell-by-Cell Basis after Alpha-Particle Microbeam Irradiation: Experimental Data and Simulations [0.03%]
α粒子微束照射后辐射诱发细胞染色体异常的实验分析及模拟研究
Antonella Testa,Francesca Ballarini,Ulrich Giesen et al.
Antonella Testa et al.
There is a continued need for further clarification of various aspects of radiation-induced chromosomal aberration, including its correlation with radiation track structure. As part of the EMRP joint research project, Biologically Weighted ...
A Novel Method to Extend a Partial-Body CT for the Reconstruction of Dose to Organs beyond the Scan Range [0.03%]
一种新颖的方法：基于部分体长CT剂量估算全身器官辐射吸收剂量
Gleb A Kuzmin,Matthew M Mille,Jae Won Jung et al.
Gleb A Kuzmin et al.
Epidemiological investigation is an important approach to assessing the risk of late effects after radiotherapy, and organ dosimetry is a crucial part of such analysis. Computed tomography (CT) images, if available, can be a valuable resour...
Analysis of Gene Expression Changes in PHA-M Stimulated Lymphocytes - Unraveling PHA Activity as Prerequisite for Dicentric Chromosome Analysis [0.03%]
植物血凝素刺激的淋巴细胞基因表达变化分析-作为臂间易位染色体分析先决条件的植物血凝素活性解析
C Beinke,M Port,R Ullmann et al.
C Beinke et al.
Dicentric chromosome analysis (DCA) is the gold standard for individual radiation dose assessment. However, DCA is limited by the time-consuming phytohemagglutinin (PHA)-mediated lymphocyte activation. In this study using human peripheral b...