MRI Study on the Changes of Bone Marrow Microvascular Permeability and Fat Content after Total-Body X-Ray Irradiation [0.03%]
全身X射线照射后骨髓微血管通透性及脂肪含量变化的磁共振研究
Kejun Wang,Yunfei Zha,Hao Lei et al.
Kejun Wang et al.
In this study, we investigated microvascular perfusion status, changes to fat content and fatty acid composition in the bone marrow of rat femurs after total-body irradiation by quantitative permeability parameters of dynamic contrast-enhan...
Rapid Decrease in KRT14 and TP53 mRNA Expression in the Buccal Mucosa of Patients Receiving Total-Body Irradiation for Allogeneic Stem Cell Transplantation [0.03%]
接受全身照射以进行同种异基因干细胞移植患者的颊粘膜KRT14和TP53 mRNA表达快速降低
J Chmara,J W L Browning,H Atkins et al.
J Chmara et al.
The only curative treatment option for relapsed patients with acute myeloid leukemia (AML) is allogeneic stem cell transplantation. Depletion of hematopoietic stem cells and leukemic blast cells is achieved through the systemic administrati...
Chronic Exposure to External Low-Dose Gamma Radiation Induces an Increase in Anti-inflammatory and Anti-oxidative Parameters Resulting in Atherosclerotic Plaque Size Reduction in ApoE-/- Mice [0.03%]
长期低剂量γ射线慢性照射通过增加抗炎和抗氧化参数在小鼠中起到缩小动脉粥样硬化斑块的作用
T G Ebrahimian,L Beugnies,J Surette et al.
T G Ebrahimian et al.
Populations living in radiation-contaminated territories, such as Chernobyl and Fukushima, are chronically exposed to external gamma radiation and internal radionuclide contamination due to the large amount of 137Cs released in the environm...
Factors Modifying the Radon-Related Lung Cancer Risk at Low Exposures and Exposure Rates among German Uranium Miners [0.03%]
影响德国铀矿工低剂量及暴露率下氡致肺癌危险因素的研究
M Kreuzer,C Sobotzki,M Schnelzer et al.
M Kreuzer et al.
It is still not fully understood whether and how factors such as time, age and smoking modify the relationship between lung cancer and radon at low exposures and exposure rates. Improved knowledge is necessary for the dose conversion of rad...
Jianyuan Song,Huojun Zhang,Zhenyu Wang et al.
Jianyuan Song et al.
Radiation-induced skin fibrosis is a detrimental and chronic disorder that occurs after radiation exposure. The molecular changes underlying the pathogenesis of radiation-induced fibrosis of human skin have not been extensively reported. Te...
DosiKit, a New Portable Immunoassay for Fast External Irradiation Biodosimetry [0.03%]
一种新型便携式免疫测定工具用于快速外部照射生物剂量测量Dosikit的研究
Julie Bensimon Etzol,Marco Valente,Sandrine Altmeyer et al.
Julie Bensimon Etzol et al.
DosiKit is a new field-radiation biodosimetry immunoassay for rapid triage of individuals exposed to external total-body irradiation. Here, we report on the validation of this immunoassay in human blood cell extracts 0.5 h after in vitro ex...
FTIR Microspectroscopy Probes Particle-Radiation Effect on HCT116 cells (p53+/+, p53-/-) [0.03%]
傅里叶变换红外显微光谱技术研究不同辐射诱导HCT116细胞(p53+/+和p53-/-)的作用差异
Jingwen Yan,Fengqiu Zhang,Qing Huang
Jingwen Yan
p53 is a crucial tumor suppressor and plays an important role in cell cycle arrest, DNA damage repair, promotion of cell senescence and apoptosis, prevention of DNA damage and maintaining genomic stability and integrity. It has been reporte...
Is there Unmeasured Indication Bias in Radiation-Related Cancer Risk Estimates from Studies of Computed Tomography? [0.03%]
CT研究中的辐射相关癌症风险评估存在未测量指示偏倚吗？
Johanna M Meulepas,Michael Hauptmann,Jay H Lubin et al.
Johanna M Meulepas et al.
Recently reported studies have associated radiation exposure from computed tomography (CT) scanning with small excess cancer risks. However, since existing medical records were used in these studies, they could not control for reasons for t...
Quantitative Proteomic Analysis of the Hippocampus of Rats with GCR-Induced Spatial Memory Impairment [0.03%]
定量蛋白组学分析地塞米松致空间学习记忆损伤大鼠海马差异蛋白质表达
Sucharita M Dutta,Melissa M Hadley,Scott Peterman et al.
Sucharita M Dutta et al.
NASA is planning future missions to Mars, which will result in astronauts being exposed to ∼13 cGy/year of galactic cosmic radiation (GCR). Previous ground-based experiments have demonstrated that low (15 cGy) doses of 1 GeV/n 56Fe ions im...
Characterization of Diffuse Intrinsic Pontine Glioma Radiosensitivity using Synchrotron Microbeam Radiotherapy and Conventional Radiation Therapy In Vitro [0.03%]
利用同步加速器微束放射治疗和常规放疗体外表征弥漫性内生脑桥胶质瘤的放射敏感性
L M Smyth,P A W Rogers,J C Crosbie et al.
L M Smyth et al.
Synchrotron microbeam radiation therapy is a promising preclinical radiotherapy modality that has been proposed as an alternative to conventional radiation therapy for diseases such as diffuse intrinsic pontine glioma (DIPG), a devastating ...