Neoadjuvant Chemoimmunotherapy in Resectable NSCLC With PD-L1 Expression < 1%: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials [0.03%]
不可切除的NSCLC伴PD-L1表达小于1%的新辅助化疗免疫治疗:随机对照试验的系统评价和网状Meta分析
Isadora Mamede,Skyler Taylor,Rafael Lara Nohmi et al.
Isadora Mamede et al.
Background: The benefit of neoadjuvant or perioperative chemoimmunotherapy in resectable non-small cell lung cancer (NSCLC) with programmed death ligand 1 (PD-L1) expression < 1% remains uncertain, as evidence is largely ...
Development and Validation of Lung Cancer Risk Prediction Models in the Singapore Chinese Population [0.03%]
在新加坡华人人群中肺癌风险预测模型的建立与验证
Yah Ru Juang,Wenjia Chen,Alvin Jing Hui Ng et al.
Yah Ru Juang et al.
Background: Despite effective screening technologies for smokers, lung cancer is often diagnosed late, especially among never-smokers who fall outside current screening guidelines. We developed 10-year risk prediction mod...
Clinical and Functional Factors Associated With Radiation Pneumonitis After Stereotactic Body Radiation Therapy for Lung Tumors: A Retrospective Cohort Study [0.03%]
立体定向体放射治疗后肺癌患者的放射性肺炎的临床及功能性影响因素:一项回顾性队列研究
Anissa Boutahir,Leila Bouazzi,Coralie Barbe et al.
Anissa Boutahir et al.
Introduction: To identify associated factors for radiation pneumonitis (RP) after stereotactic body radiation therapy (SBRT), focusing on pretreatment pulmonary function parameters and baseline clinical characteristics. ...
Real World Outcomes for the Efficacy and Safety of Osimertinib in Black Patients With Nonsmall Cell Lung Cancer [0.03%]
关于奥希替尼在非小细胞肺癌黑人患者中有效性和安全性的实际转归情况研究
Mattie Kilpatrick,Parker Gundersen,Katherine OReilly et al.
Mattie Kilpatrick et al.
Purpose: Epidermal growth factor receptor (EGFR) mutations occur in approximately 20%-30% of nonsmall cell lung cancers (NSCLC). Osimertinib, a third-generation EGFR tyrosine kinase inhibitor, irreversibly binds to EGFR m...
High Adherence Over a Decade of Annual Lung Cancer Screening in an Occupational Cohort [0.03%]
职业队列中十年年度肺癌筛查的高依从性研究
Steven B Markowitz,Bian Liu,Albert Miller et al.
Steven B Markowitz et al.
Introduction: Adherence to an annual low-dose chest CT (LDCT) scan regimen is essential to lung cancer screening success but has been scarcely studied beyond 2 annual CT scans. ...
Treatment Attrition From Surgery to Adjuvant Therapy in Stage IIB and IIIA Lung Adenocarcinoma: A National Cancer Database Analysis [0.03%]
基于国家癌症数据库分析的IIB和IIIA期肺腺癌患者外科治疗后辅助治疗依从性下降的状况
Omar Bushara,Mohammad S Farooq,Shawn Ahn et al.
Omar Bushara et al.
Introduction: Lung cancer is the leading cause of cancer-related death. For pathologic stage IIB/IIIA tumors, standard of care may include surgery followed by adjuvant therapy. The proportion of patients who do not receiv...
Impact of Immune Checkpoint Inhibitor-Combined Chemotherapy as First-Line Treatment for Non-Small Cell Lung Cancer With Brain Metastases [0.03%]
免疫检查点抑制剂联合化疗作为非小细胞肺癌脑转移一线治疗的影响
Amira Aliouat,Agathe Chareire,Teo Bodergat et al.
Amira Aliouat et al.
Immune checkpoint inhibitor-combined chemotherapy (chemo-ICI) is a cornerstone treatment for metastatic non-small cell lung cancer (NSCLC) without oncogenic addictions. However, immunotherapy's efficacy in patients with brain metastases rem...
High Programmed Death-Ligand 1 Expression is Associated With a Shorter Progression Free Survival in ALK-Rearranged Lung Cancer Patients Treated With First Line Tyrosine Kinase Inhibitors [0.03%]
程序性死亡配体1高表达与酪氨酸激酶抑制剂一线治疗间变淋巴瘤激酶重排型肺癌患者更短的无进展生存期有关
Yunan Nie,Alyse Staley,Trista K Hinz et al.
Yunan Nie et al.
Background: Although ALK-positive non-small cell lung cancer (NSCLC) derives limited benefit from immune checkpoint inhibitors, PD-L1 expression is frequently elevated at diagnosis. The clinical relevance of PD-L1 express...
Predicting Radiation-Induced Esophagitis in Locally Advanced NSCLC Using Baseline Clinical Factors: A Model From the Japan Lung Cancer Society Integrated Phase II-III Database [0.03%]
基于日本肺癌学会集成II-III期数据库的基线临床因素预测局部晚期NSCLC放射性食管炎发生的模型研究
Yuji Uehara,Kageaki Watanabe,Jun Tamura et al.
Yuji Uehara et al.
Background: Radiation-induced esophagitis (RE) is common during thoracic radiotherapy for NSCLC. We assessed its clinical impact and developed a model to predict grade ≥ 2 acute RE in patients with unresectable stage III...
Brief Report: Improving Lung Cancer Screening Rates: A Pilot Program for Low-Dose CT Implementation in a Community Cancer Center [0.03%]
低剂量螺旋CT肺癌筛查项目在社区肿瘤医院的实施试点研究报告
Maha Zafar,Manaswini Krishnakumar,Natasha Dudiki et al.
Maha Zafar et al.
Lung cancer remains the leading cause of cancer-related mortality worldwide, with low survival rates due to late-stage diagnosis. We conducted a pilot lung cancer screening program initiated at our community cancer center to improve the uti...