Incidence and Risk Factors of Non-neutropenic Enterocolitis With Adjuvant Capecitabine and Oxaliplatin Chemotherapy in Colorectal Cancer [0.03%]
辅助卡培他滨和奥沙利铂化疗结直肠癌患者非中性粒细胞减少性肠炎的发病率及其危险因素分析
Guillaume Roy,Rakan Okde,Olivia Cull et al.
Guillaume Roy et al.
Background: Following the IDEA collaboration, the use of capecitabine and oxaliplatin (CAPOX regimen) for adjuvant colorectal cancer treatment has increased. While CAPOX is associated with higher rates of diarrhea, non-ne...
The Impact of Surgical Resection in Early Onset Colorectal Cancer Patients With Liver Limited Disease [0.03%]
早发性结直肠癌肝转移局限患者的手术治疗效果分析
Andrea Pretta,Pina Ziranu,Francesca Bergamo et al.
Andrea Pretta et al.
Background: Recent studies have shown an increased incidence of early-onset CRC (EO-CRC), particularly in advanced stages and with metastatic disease. Our study aimed to evaluate the role of metastasectomies related to th...
Phase II Study of Pembrolizumab Plus Capecitabine and Bevacizumab for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer [0.03%]
帕博利尤单抗联合卡培他滨和贝伐珠单抗治疗微卫星稳定型/错配修复阳性转移性结直肠癌的Ⅱ期研究
Andrea Bocobo,Julia Whitman,Bridget P Keenan et al.
Andrea Bocobo et al.
Background: This study evaluated the safety, tolerability and preliminary efficacy of pembrolizumab in combination with capecitabine and bevacizumab in microsatellite stable (MSS) metastatic colorectal cancer (mCRC). ...
Consistency of Radiological Staging in Resectable Mismatch-Repair Proficient Colon Cancer: An Interobserver Agreement Study [0.03%]
mismatch repair proficient可切除结肠癌的放射学分期的一致性：一项关于观察者间一致性方面的研究
Vincenzo Nasca,Gabriele Tinè,Marta Vaiani et al.
Vincenzo Nasca et al.
Background: Reproducibility and accuracy of radiological classification with CT imaging is crucial for selecting patients with resectable, nonmetastatic colon cancer (CC) who may benefit from neoadjuvant strategies. ...
Phase Ib Study to Assess the Safety of Neoadjuvant Trifluridine/Tipiracil With Concurrent Radiation in Resectable Stage II/III Rectal Cancer: The FIERCE Study [0.03%]
术前曲氟尿苷联合泰Leap与同期放疗治疗可切除的II/III期直肠癌的Ib期研究：FIERCE研究
Emerson Y Chen,Nima Nabavizadeh,Nicholas D Kendsersky et al.
Emerson Y Chen et al.
Background: Trifluridine has demonstrated superior radio-sensitizing ability in vitro, and trifluridine/tipiracil (FTD/TPI) confers clinical benefit in metastatic colorectal cancer. The FIERCE trial (NCT04104139) sought t...
Lenvatinib Plus Pembrolizumab for Patients With Previously Treated Advanced Colorectal Cancer: Results From the Phase II LEAP-005 Study [0.03%]
仑伐替尼联合派姆单抗治疗既往接受过治疗的晚期结直肠癌患者：LEAP-005Ⅱ期试验结果
Iván Victoria Ruiz,Nataliya V Uboha,Rahima Jamal et al.
Iván Victoria Ruiz et al.
Background: Current treatments for patients with previously treated metastatic colorectal cancer (CRC) have poor outcomes. LEAP-005 (ClinicalTrials.gov, NCT03797326) was a multicohort, open-label phase II study evaluating...
Circulating Tumor DNA as a Biomarker for Recurrence After Curative Resection of Colorectal Cancer Liver Metastases: A Systematic Review and Meta-Analysis [0.03%]
Atta Ullah Khan,Abdul Ahad Mehboob,Asraa Abdulsahib Yousif et al.
Atta Ullah Khan et al.
Colorectal liver metastases (CRLM) remain a leading cause of cancer-related mortality, with recurrence rates of 50 to 70% following curative-intent hepatic resection. Circulating tumor DNA (ctDNA) has emerged as a promising biomarker for mi...
Brain Metastasis From Anal Canal Squamous Cell Carcinoma: A Rare Case Report and Systematic Review [0.03%]
罕见的肛管鳞状细胞癌脑转移病例报告及系统回顾
Miriam Tomaciello,Mauro Palmieri,Massimo Corsini et al.
Miriam Tomaciello et al.
Anal canal squamous cell carcinoma (ACSCC) is a rare malignancy, accounting for approximately 2% of all colorectal cancers. Brain metastases originating from this primary site are exceedingly uncommon and scarcely documented. The aim of thi...
Successful Encorafenib and Cetuximab Re-Challenge Combined With Nivolumab in BRAF V600E Mutated, Mismatch-Repair-Proficient Metastatic Colorectal Cancer - A Case Report From the AGMT mCRC Registry [0.03%]
恩考芬尼和西妥昔单抗联合纳武利尤单抗治疗BRAF V600E突变、错配修复完整型转移性结直肠癌的再挑战研究——AGMT mCRC注册报告的一个病例研究报告
Iason Theodorou,Ronald Heregger,Richard Greil et al.
Iason Theodorou et al.
The Role of Systemic Chemotherapy to Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Patients With Appendiceal Cancers [0.03%]
系统化疗在回盲部肿瘤腹腔细胞减灭术及腹腔热灌注化疗中作用的专家共识（2018版）
Gagandeep Brar,Dani Castillo,Thinzar Lwin et al.
Gagandeep Brar et al.
Background: Appendiceal cancer frequently presents with peritoneal metastases. Cytoreductive surgery combined (CRS) with heated intraperitoneal chemotherapy (HIPEC) is currently standard practice for metastatic appendicea...