Seán P Barry,Paul A Townsend
Seán P Barry
Our understanding of the molecular processes which regulate cardiac function has grown immeasurably in recent years. Even with the advent of β-blockers, angiotensin inhibitors and calcium modulating agents, heart failure (HF) still remains...
Barbara Cisterna,Marco Biggiogera
Barbara Cisterna
In this chapter we describe the status of the research concerning the nucleolus, the major nuclear body. The nucleolus has been recognized as a dynamic organelle with many more functions than one could imagine. In fact, in addition to its f...
Mitochondrial dynamics [0.03%]
线粒体动力学
Jürgen Bereiter-Hahn,Marina Jendrach
Jürgen Bereiter-Hahn
Mitochondrial dynamics is a key feature for the interaction of mitochondria with other organelles within a cell and also for the maintenance of their own integrity. Four types of mitochondrial dynamics are discussed: Movement within a cell ...
Philipp Skroblin,Solveig Grossmann,Gesa Schäfer et al.
Philipp Skroblin et al.
The second messenger cyclic adenosine monophosphate (cAMP), which is produced by adenylyl cyclases following stimulation of G-protein-coupled receptors, exerts its effect mainly through the cAMP-dependent serine/threonine protein kinase A (...
Gerhard Schlosser
Gerhard Schlosser
Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line, profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and ganglia of the vertebrate head. Recent evidence suggests that all...
Kevin Blauth,Swati Banerjee,Manzoor A Bhat
Kevin Blauth
Glial cells are critical players in every major aspect of nervous system development, function, and disease. Other than their traditional supportive role, glial cells perform a variety of important functions such as myelination, synapse for...
Patricia Costa,Maddy Parsons
Patricia Costa
Adhesion to the extracellular matrix (ECM) and to adjacent cells is a fundamental requirement for survival, differentiation, and migration of numerous cell types during both embryonic development and adult homeostasis. Different types of ad...
Boris M Slepchenko,Leslie M Loew
Boris M Slepchenko
The Virtual Cell (VCell) is a unique computational environment for modeling and simulation of cell biology. It has been specifically designed to be a tool for a wide range of scientists, from experimental cell biologists to theoretical biop...
Takuya Matsuo,Masahiro Ishiura
Takuya Matsuo
The unicellular green alga Chlamydomonas reinhardtii has long been used in research on circadian rhythm. Various circadian rhythms in behavior and physiology including phototaxis, chemotaxis, the cell division cycle, UV sensitivity, stickin...
Impact of ATP-binding cassette transporters on human immunodeficiency virus therapy [0.03%]
ATP结合盒转运蛋白对人类免疫缺陷病毒治疗的影响
Johanna Weiss,Walter Emil Haefeli
Johanna Weiss
Even though potent antiretrovirals are available against human immunodeficiency virus (HIV)-1 infection, therapy fails in a significant fraction of patients. Among the most relevant reasons for treatment failure are drug toxicity and side e...