Poojan Chaniyara,Mohnish Gandhi,Dhruvesh Maiya et al.
Poojan Chaniyara et al.
Systemic toxicity and off target effects are some of the major drawbacks of traditional, broad-spectrum therapies. Nanotechnology effectively counters these by offering precise, targeted alternatives and hence, reshaping biomedical engineer...
MRI acute/sub-acute ischemic stroke segmentation with deep learning: A comprehensive review [0.03%]
基于深度学习的急性/亚急性缺血性卒中MRI分割综述
Mohammad Alshurbaji,Maregu Assefa,Said Boumaraf et al.
Mohammad Alshurbaji et al.
The segmentation of ischemic stroke lesions from Magnetic Resonance Imaging (MRI) images using deep learning (DL) techniques has emerged as a critical area of research in medical imaging. This article provides a comprehensive review of the ...
Bioink-based 3D bioprinting: Paving the path for regenerative medicine [0.03%]
基于生物墨水的3D生物打印：铺就再生医学的道路
Dhruvi Dipakbhai Patel,Shalu Jha,Khushboo Virpankar et al.
Dhruvi Dipakbhai Patel et al.
Three-dimensional (3D) bioprinting has come a long way to have emerged as a transformative technology in bio-fabrication. Bioinks with specific attributes of cellular compatibility, mechanical strength, printability, and biodegradability re...
Santhosh Kumar Yasam,N Vignesh,Senthilkumar Rajagopal
Santhosh Kumar Yasam
Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation and redox imbalance. It has emerged as a pivotal mechanism implicated in various diseases, including cancer, chronic kidney diseases (CKD), neurodege...
Shreya Dave,Juni Banerjee,Shuvomoy Banerjee et al.
Shreya Dave et al.
Understanding the pathologies related to neurological issues, viz. Alzheimer's disease (AD), brain tumors, and multiple sclerosis (MS) are complex and still lack effective therapeutics. Management of the global health burden caused by the e...
Minh-Dat Quoc Tang,Bao-Nhien Au,Van Khanh Hoang et al.
Minh-Dat Quoc Tang et al.
The development and application of nanoscale materials for tackling medical and health-related challenges is garnering considerable interest. By loading or attaching small molecule drugs in structure, these nanocarriers can improve the phar...
Cristina Pérez-Montes,Elena Lavado-Fernández,Inés Martínez-Rojo et al.
Cristina Pérez-Montes et al.
For eukaryotic organisms the maintenance and regulation of cellular homeostasis is essential. This process requires continuous elimination of cellular debris, including misfolded, oxidized, and aggregated proteins, and damaged/obsolete orga...
Impact of different exercise modalities on mitophagy in human skeletal muscle [0.03%]
不同运动方式对人类骨骼肌自噬的影响
Cristóbal Muñoz-Medina,Alfonso Carriel-Nesvara,Javier Botella et al.
Cristóbal Muñoz-Medina et al.
Exercise induces profound mitochondrial adaptations in skeletal muscle, with different modalities uniquely influencing different branches of mitochondrial quality control (MQC). This review examines how endurance, resistance, and high-inten...
Non-selective and selective autophagy as mediators of mechanical forces [0.03%]
非选择性和选择性自噬在机械力介导中的作用
Maraiza Alves Teixeira,Nicolas Dupont
Maraiza Alves Teixeira
Autophagy is a fundamental cell biological process that controls the quality and quantity of the eukaryotic cytoplasm. Dysfunctional autophagy, when defective or excessive, has been linked to human pathologies. Autophagy can randomly degrad...
Joan Villarroya,Albert Blasco-Roset,Marta Giralt
Joan Villarroya
Brown adipose tissue (BAT) is the main site of adaptive thermogenesis, a heat-producing process essential for maintaining body temperature, especially in cold environments. While abundant in newborns, BAT is also present in adults, where it...