Radiation-induced immune response in novel radiotherapy approaches FLASH and spatially fractionated radiotherapies [0.03%]
新型放射治疗中的FLASH和空间分段放疗引起的辐射免疫反应
Annaig Bertho,Lorea Iturri,Yolanda Prezado
Annaig Bertho
The last several years have revealed increasing evidence of the immunomodulatory role of radiation therapy. Radiotherapy reshapes the tumoral microenvironment can shift the balance toward a more immunostimulatory or immunosuppressive microe...
Benoît Lecoester,Mylène Wespiser,Amélie Marguier et al.
Benoît Lecoester et al.
Chemoradiation (CRT) is a conventional therapy used in local cancers, especially when they are locally advanced. Studies have shown that CRT induces strong anti-tumor responses involving several immune effects in pre-clinical models and hum...
Mara De Martino,Camille Daviaud,Edgar Hajjar et al.
Mara De Martino et al.
Fatty acid metabolic reprogramming has emerged as a major regulator of anti-tumor immune responses with large body of evidence that demonstrate its ability to impact the differentiation and function of immune cells. Therefore, depending on ...
Are charged particles a good match for combination with immunotherapy? Current knowledge and perspectives [0.03%]
带电粒子与免疫治疗联合的现状及展望
A Helm,C Totis,M Durante et al.
A Helm et al.
Charged particle radiotherapy, mainly using protons and carbon ions, provides physical characteristics allowing for a volume conformal irradiation and a reduction of the integral dose to normal tissue. Carbon ion therapy additionally featur...
Myeloid-derived suppressor cells: Emerging players in cancer and beyond [0.03%]
髓源抑制细胞:癌症及其相关疾病中的新角色
Carlos Jiménez-Cortegana,Lorenzo Galluzzi
Carlos Jiménez-Cortegana
Knowing the myeloid-derived suppressor cells: Another enemy of sarcomas patients [0.03%]
了解髓系源性抑制细胞:肉瘤患者的另一敌人
Daniel J García-Domínguez,Víctor Sánchez-Margalet,Luis de la Cruz-Merino et al.
Daniel J García-Domínguez et al.
Sarcomas are heterogeneous and aggressive malignant tumors with variable responses to current standard treatments being usually incurable for those patients with metastatic and unresectable diseases. The lack of curative strategies has led ...
Myeloid-derived suppressor cells in head and neck squamous cell carcinoma [0.03%]
头颈部鳞状细胞癌中的髓系源性抑制细胞
Jing-Yu He,Fang-Yi Huo,Hong-Chao Tang et al.
Jing-Yu He et al.
Myeloid-derived suppressor cells (MDSCs), which originated from hematopoietic stem cells, are heterogeneous population of cells that have different differentiation patterns and widely presented in tumor microenvironment. For tumor research,...
Myeloid-derived suppressor cells: A new emerging player in endometriosis [0.03%]
髓源性抑制细胞:子宫内膜异位症中的新晋角色
Tao Zhang,Ying He,Gene Chi Wai Man et al.
Tao Zhang et al.
Endometriosis is a common gynecological disorder defined by the presence of endometrial tissue outside the uterus. This is commonly associated with chronic pelvic pain, infertility, and dysmenorrhea, which occurs in approximately 10% of wom...
Emerging avenues linking myeloid-derived suppressor cells to periodontal disease [0.03%]
髓源抑制细胞与牙周病关系的研究进展
Ana Gabriela Leija-Montoya,Javier González-Ramírez,Idanya Serafín-Higuera et al.
Ana Gabriela Leija-Montoya et al.
Periodontal disease is one of the most common inflammatory disorders in humans. Gingivitis is the mildest form of periodontal disease and its progression can lead to periodontitis, an inflammatory disease characterized by soft tissue damage...
Role of myeloid-derived suppressor cells during Trypanosoma cruzi infection [0.03%]
泰勒虫感染期间髓系源性抑制细胞的作用
Eliana Borgna,Estefanía Prochetto,Juan Cruz Gamba et al.
Eliana Borgna et al.
Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, is the third largest parasitic disease burden globally. Currently, more than 6 million people are infected, mainly in Latin America, but international migration has tu...