The interplay between gamma delta (γδ) T cells and cellular stress pathways in the pathogenesis of emerging human viral zoonoses [0.03%]
博弈دل塔（γδ）T细胞与细胞压力通路在新兴人畜共患病毒发病机制中的作用
Shovan Dutta,Anirban Ganguly,Sounak Ghosh Roy
Shovan Dutta
This chapter examines the intricate relationship between gamma-delta (γδ) T cells and cellular stress pathways in the context of emerging infectious diseases. γδ T cells, a distinct subset of lymphocytes, are integral to the innate immu...
Deciphering the role of γδ T cells in skin inflammatory diseases: Insights from psoriasis, atopic dermatitis, and alopecia areata [0.03%]
揭秘γδT细胞在皮肤炎症性疾病中作用：来自银屑病、特应性皮炎和斑秃的启示
Ines Espeleta,Radu Alecsandru Gorgon,Francisco Sánchez-Madrid et al.
Ines Espeleta et al.
Gamma delta (γδ) T lymphocytes are a heterogeneous population of immune cells that correspond between 1 % and 5 % of mice lymphoid tissues and human blood lymphocytes. However, their prevalence increases markedly in epithelial and mucosal...
Human T-cell receptor inborn errors of immunity shed light on the real-life role of γδ vs αβ T lymphocytes [0.03%]
人T细胞受体先天性免疫缺陷病揭示了γδ与αβ T淋巴细胞在真实生活中的作用差异
Ana V Marin,Daniel Chacon-Arguedas,Ivan Estevez-Benito et al.
Ana V Marin et al.
T lymphocytes are critical components of adaptive immunity. They are involved, together with other leucocytes, in defense against pathogens, including viruses, bacteria, fungi and parasites. Mature T cells include two subsets, αβ and γδ...
Gamma-delta T cells in breast cancer: Dual role in tumor immunity and emerging therapeutic approaches [0.03%]
γδT细胞在乳腺癌中的作用及治疗前景：肿瘤免疫的双重角色及新兴治疗方法
Silvia Silva-Romeiro,María Luisa Sánchez-León,Carlos Jiménez-Cortegana et al.
Silvia Silva-Romeiro et al.
Gamma delta (γδ) T cells are a unique subset of T lymphocytes capable of bridging innate and adaptive immunity. Unlike αβ T lymphocytes, γδ T cells bypass the need for Major Histocompatibility Complex (MHC)-restricted antigen presenta...
Carolina C Jancic
Carolina C Jancic
gamma-delta (γδ) T cells reside in numerous tissues, recognize a vast array of antigens, and perform highly specialized functions. They have participated in antimicrobial and antitumor immunity, in modulation the immune responses and in t...
Igor Bychkov,David L Wiest
Igor Bychkov
While the function of αβ T cells in host defense is quite well understood, insight into the role that γδ T cells play in health and disease has lagged behind, despite their discovery approximately forty years ago. Because γδ T cells r...
Pedro Chacón,Ana María Múnera-Rodríguez,Camila Leiva-Castro et al.
Pedro Chacón et al.
Allergic diseases including asthma, allergic rhinitis, food allergies, and atopic dermatitis arise from an overactive immune response following exposure to allergens. The increasing prevalence of these conditions highlights the urgent need ...
Unraveling the role of γδ T cells in inflammatory bowel disease: Development and prevention strategies [0.03%]
γδ T细胞在炎症性肠病中的作用及防治策略研究进展
Ana María Múnera-Rodríguez,Camila Leiva-Castro,Pedro Chacón et al.
Ana María Múnera-Rodríguez et al.
Inflammatory bowel diseases (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), are autoimmune disorders characterized by heterogeneous clinical manifestations and dysregulated immune responses. Central to this pathophysio...
Jiayu Peng,Hui Qiu,Lin-Lin Bu et al.
Jiayu Peng et al.
Head and neck squamous cell carcinoma (HNSCC) is a prevalent and aggressive malignant tumor with poor clinical prognosis. The immune system plays a critical role in tumor surveillance and response to therapy. Among various immune cell popul...
The antiviral potential of Vγ9Vδ2 T cells: Therapeutic implications for immunocompromised adult and pediatric hosts [0.03%]
Vγ9Vδ2 T细胞的抗病毒潜力：免疫抑制成人和儿童患者治疗的意义
Veronica Bordoni,Federica Guarracino,Angela Lorusso et al.
Veronica Bordoni et al.
A growing number of pediatric and adult subjects worldwide suffer from impaired immune response to pathogens, due to both disease and medical treatments. Different types of immunodeficiency or immunosuppressive drugs may affect different as...