mtDNA Copy Number Contributes to All-Cause Mortality of Lacunar Infarct in a Chinese Prospective Stroke Population [0.03%]
线粒体DNA拷贝数通过影响腔隙性梗死导致 chinese prospective stroke population中全因死亡率增加
Li Song,Tianlong Liu,Yan Song et al.
Li Song et al.
The study aimed to investigate the relationship between mtDNA copy number and the risk of all-cause mortality in stroke. One thousand four hundred eighty-four stroke patients were documented including 273 deaths (127 thrombosis, 52 lacunar,...
Biqing Wang,Wenbin Cai,Ding Ai et al.
Biqing Wang et al.
Deubiquitinases (DUBs) are a major component of the ubiquitin-proteasome system in eukaryotic cells; the system plays a crucial role in many biological processes, such as inflammation, oxidative stress, and cell apoptosis, which are importa...
Effect of Smartphone-Based Telemonitored Exercise Rehabilitation among Patients with Coronary Heart Disease [0.03%]
基于智能手机的远程监控有指导锻炼康复对冠心病患者的疗效研究
Yanxin Song,Chuan Ren,Ping Liu et al.
Yanxin Song et al.
The aim of this study was to investigate the effects of telemonitored exercise rehabilitation on patients with coronary heart disease (CHD) in China. Ninety-six patients with stable CHD were included and analyzed (48 in telemonitored group ...
Randomized Controlled Trial
Journal of cardiovascular translational research. 2020 Aug;13(4):659-667. DOI:10.1007/s12265-019-09938-6 2020
Margarida Lorigo,Melissa Mariana,Nelson Oliveira et al.
Margarida Lorigo et al.
Cardiovascular diseases (CVD) are one of the leading causes of death worldwide. Testosterone (T) is an important sex hormone that triggers several genomic and non-genomic pathways, leading to improvements of several cardiovascular risk fact...
Inhibition of MicroRNA-206 Ameliorates Ischemia-Reperfusion Arrhythmia in a Mouse Model by Targeting Connexin43 [0.03%]
microRNA-206通过靶向缝隙连接蛋白43调控小鼠缺血再灌注心律失常
Yan Jin,Tianyi Zhou,Qiuting Feng et al.
Yan Jin et al.
Reperfusion arrhythmias (RA) are an important cause of sudden cardiac death and is closely associated with gap junction protein in the heart, connexin 43 (Cx43). This study is aimed at elucidating the molecular association between microRNA-...
Intermittent Occlusion of the Superior Vena Cava Reduces Cardiac Filling Pressures in Preclinical Models of Heart Failure [0.03%]
上腔静脉间断闭塞可降低心力衰竭模型中的心脏充盈压
Navin K Kapur,Lara Reyelt,Paige Crowley et al.
Navin K Kapur et al.
Congestion is a major determinant of clinical outcomes in heart failure (HF). We compared the acute hemodynamic effects of occlusion of the superior (SVC) versus the inferior vena cava (IVC) and tested a novel SVC occlusion system in swine ...
The Effects of Valvular Heart Disease on Atrial Conduction During Sinus Rhythm [0.03%]
窦性心律下瓣膜性心脏病对房室传导的影响
Lisette J M E van der Does,Eva A H Lanters,Christophe P Teuwen et al.
Lisette J M E van der Does et al.
Different arrhythmogenic substrates for atrial fibrillation (AF) may underlie aortic valve (AV) and mitral valve (MV) disease. We located conduction disorders during sinus rhythm by high-resolution epicardial mapping in patients undergoing ...
Bilateral Deep Vein Thrombosis, Vena Cava Agenesis, and Renal Abnormalities: KILT Syndrome-A Case Report and Literature Review [0.03%]
双侧深静脉血栓、下腔静脉缺如和肾异常：KILT综合征一例并文献复习
Sergio Moragón-Ledesma,Francisco Galeano-Valle,Enrique Calleja-Cartón et al.
Sergio Moragón-Ledesma et al.
KILT (kidney and IVC abnormalities with leg thrombosis) syndrome is a very rare condition that associates inferior vena cava abnormalities, renal defects, and venous thrombosis. These vascular disorders appear in 0.6-2% of patients with car...
Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes [0.03%]
急性冠脉综合征后慢性及医院获得性贫血患者的预后
Thabo Mahendiran,David Nanchen,Baris Gencer et al.
Thabo Mahendiran et al.
Discharge anaemia is common following acute coronary syndromes (ACS). However, it is unknown if chronic anaemia (CA) and hospital-acquired anaemia (HAA) are associated with similar outcomes. In this retrospective analysis of 4083 ACS admiss...
XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction [0.03%]
XPO1基因治疗可减轻慢性心肌梗死大鼠的心功能障碍
María García-Manzanares,Estefanía Tarazón,Ana Ortega et al.
María García-Manzanares et al.
Transcriptomic signature of XPO1 was highly expressed and inversely related to left ventricular function in ischemic cardiomyopathy patients. We hypothesized that treatment with AAV9-shXPO1 attenuates left ventricular dysfunction and remode...