Glucagon-like Peptide-1 Receptor Dependent Signaling in Cardiovascular Health and Disease: A Mini-review [0.03%]
胰高血糖素样肽-1受体依赖性信号在心血管健康和疾病中的作用:综述型文章
Meng-Piao Lin,Bing-Jie Xue,Xiao-Jie Bai
Meng-Piao Lin
Glucagon-like peptide-1 (GLP-1) is a hormone mainly produced by intestinal L cells after meal, and its main functions include enhancing glucose-dependent insulin secretion, promoting insulin biosynthesis, inhibiting glucagon secretion, inhi...
Lacylation of Stearoyl-CoA Desaturase-1 Contributes to the Myocardial Ischemia-Reperfusion Injury Through Regulating Wnt/β-Catenin Signaling [0.03%]
肉毒碱棕榈酰转移酶-1乳酰化通过调控Wnt/β-catenin信号通路参与心肌缺血再灌注损伤
Ying Zhang,Junshi Zhang,Yaling Zhang et al.
Ying Zhang et al.
Myocardial ischemia-reperfusion injury (MIRI) involves tissue damage following restoration of blood flow. Stearoyl-CoA desaturase 1 (SCD1), associated with metabolic disorders, may contribute to MIRI. This study investigated the mechanism o...
Meiyu Hu,Shihui Zang,Yifu Chen et al.
Meiyu Hu et al.
Computational Fluid Dynamics Simulation of Endothelium-Modulated Thrombosis [0.03%]
调控内皮细胞的血栓形成计算流体模拟研究
Wenxuan He,Abhishek Karmakar,James F Antaki
Wenxuan He
The development of blood-wetted artificial organs is limited by thrombosis on synthetic biomaterial surfaces. In contrast, the endothelium of the vasculature creates a natural barrier to both thrombosis and pannus growth. Consequently, effo...
Response to the letter to the Editor: Comment on "A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity" [0.03%]
致编辑的回信:“检测亚临床动脉粥样硬化的潜在指标:关于严重肥胖患者核磁共振血脂谱的见解”
Júlia Carmona-Maurici,Iratxe Eskubi-Turró,Eva Pardina
Júlia Carmona-Maurici
Meiyu Hu,Tingting Yang,Xinxiu Meng et al.
Meiyu Hu et al.
Comment on "A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity" [0.03%]
对“检测亚临床动脉粥样硬化的潜在比率:严重肥胖患者NMR血脂谱的深入研究”的评论
S Dhanya Dedeepya,Vaishali Goel,Nivedita Nikhil Desai
S Dhanya Dedeepya
Pressure Measurements Obtained from Intraosseous Access: Potential Clinical Applications Explored Using a Porcine Model [0.03%]
骨内通路获取的压力测量:利用猪模型探讨其潜在临床应用
Joerg Reifart,Nida Asif,Paul Iaizzo
Joerg Reifart
Intraosseous access, the fastest access in emergencies, is exclusively used for delivering medications or fluids. The correlation between intraosseous and arterial pressures remains unclear. This study aimed to explore this correlation at b...
Transcription Factor SP1 Drives Myocardial Ischemia/reperfusion Injury By Transcription Activation-mediated GADD45G Upregulation [0.03%]
转录因子SP1通过转录激活介导GADD45G上调驱动心肌缺血再灌注损伤
Yaping Wang,Jianying Xue,Mingliang Cui et al.
Yaping Wang et al.
Myocardial ischemia-reperfusion injury (MIRI) is an unresolved clinically fatal complication in the management of acute myocardial infarction (AMI). Growth arrest and DNA damage-inducible gene 45 Gamma (GADD45G) plays a vital role in the re...
MiR-499-5P/PACS2/TRPV1 Axis Maintains Mitochondrial Homeostasis and Left Ventricular Function after Extreme Cold Stress [0.03%]
MiR-499-5P/PACS2/TRPV1轴维持极端寒冷刺激后的线粒体稳态和左心室功能
Renzheng Chen,Yan Ma,Sijia Chen et al.
Renzheng Chen et al.
Exposure to cold environments is physiologically challenging, with extreme cold stress (ECS) impairing the function of the left ventricle (LV) of the heart. We aimed to determine the role and mechanism of action of the miR-499-5p/phosphofur...