Cardiovascular Volume Reserve in Patients with Heart Failure and Reduced Ejection Fraction [0.03%]
射血分数降低的心力衰竭患者的心血管容量储备
Petra Nijst,Pieter Martens,Frederik H Verbrugge et al.
Petra Nijst et al.
This study aimed to investigate the relationship between intravascular volume and intracardiac filling pressures in stable HF patients with reduced ejection fraction (HFrEF). A total of 40 HFrEF patients (LVEF 36 ± 10%) (10 subjects with a...
Facilitation Through Aggrastat or Cangrelor Bolus and Infusion Over PrasugreL: a MUlticenter Randomized Open-label Trial in PatientS with ST-elevation Myocardial InFarction Referred for PrimAry PercutaneouS InTERvention (FABOLUS FASTER) Trial: Design and Rationale : The FABOLUS FASTER Trial [0.03%]
通过使用阿昔单抗或替格瑞洛注射和持续输注优于普拉格雷：在ST段抬高型心肌梗死并接受直接皮质冠状动脉介入治疗的患者中进行的一项多中心、开放标签随机对照试验（FABOLUS FASTER研究）：设计与合理性
Giuseppe Gargiulo,Giovanni Esposito,Plinio Cirillo et al.
Giuseppe Gargiulo et al.
Antithrombotic therapy is a critical component of the management of ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI). Rapid and profound inhibition of platelet reactivity has ...
Randomized Controlled Trial
Journal of cardiovascular translational research. 2021 Feb;14(1):110-119. DOI:10.1007/s12265-020-09969-4 2021
The Effect of Antihypertensive Therapy on Left Ventricular Longitudinal Strain: Missing Part of the Puzzle [0.03%]
抗高血压治疗对左心室纵向应变的影响：拼图中缺失的部分
Marijana Tadic,Cesare Cuspidi
Marijana Tadic
There is no consensus regarding the benefit of antihypertensive therapy on left ventricular structure and function. The most of studies investigated the effect of therapy on left ventricular hypertrophy, less studies were focused on left ve...
Cardiovascular Risk Assessment and Therapeutic Implications in Rheumatoid Arthritis [0.03%]
风湿性关节炎的心血管风险评估及治疗意义
Juli Halacoglu,Leticia A Shea
Juli Halacoglu
Patients with rheumatoid arthritis (RA) suffer from a magnitude of excess cardiovascular risk. A paradoxical lipid pattern has been observed in rheumatoid arthritis patients where low levels of total cholesterol and low-density lipoprotein ...
Human In Vitro Models for Assessing the Genomic Basis of Chemotherapy-Induced Cardiovascular Toxicity [0.03%]
化疗引起的心血管毒性的基因组基础的体外评价模型
Emily A Pinheiro,Tarek Magdy,Paul W Burridge
Emily A Pinheiro
Chemotherapy-induced cardiovascular toxicity (CICT) is a well-established risk for cancer survivors and causes diseases such as heart failure, arrhythmia, vascular dysfunction, and atherosclerosis. As our knowledge of the precise cardiovasc...
Impact of Atrial Fibrillation on In-Hospital Mortality and Thromboembolic Complications after Left Ventricular Assist Device Implantation [0.03%]
左心室辅助装置植入术后房颤对住院死亡率和血栓并发症的影响
Vanessa Blumer,Miguel Ortiz Bezara,Veraprapas Kittipibul et al.
Vanessa Blumer et al.
The association between atrial fibrillation (AF) and thromboembolic (TE) complications in left ventricular assist device (LVAD) recipients is controversial, and there is paucity of large-scale data evaluating the impact of AF on early outco...
Atherosclerosis: Insights into Vascular Pathobiology and Outlook to Novel Treatments [0.03%]
动脉粥样硬化：血管病生物学新见解及展望新型治疗方法
Marc P Wolf,Patrick Hunziker
Marc P Wolf
The pathobiology of atherosclerosis and its current and potential future treatments are summarized, with a spotlight on three central cell types involved: (i) endothelial cells (ECs), (ii) macrophages, and (iii) vascular smooth muscle cells...
Role of NLRP3-Inflammasome/Caspase-1/Galectin-3 Pathway on Atrial Remodeling in Diabetic Rabbits [0.03%]
NLRP3炎性小体/Caspase-1/Galectin-3信号通路在糖尿病兔心房重构中的作用研究
Xiaohan Wu,Yang Liu,Daimiao Tu et al.
Xiaohan Wu et al.
Both diabetes mellitus (DM) and atrial fibrillation (AF) are usually associated with enhanced inflammatory response. The effect of the "NACHT, LRR and PYD domain containing protein 3" (NLRP3)-inflammasome/caspase-1/galectin-3 pathway and th...
Acute In Vivo Functional Assessment of a Biodegradable Stentless Elastomeric Tricuspid Valve [0.03%]
可降解的三尖瓣无支架弹性阀的急性体内功能评估
Garrett N Coyan,Lindemberg da Mota Silveira-Filho,Yasumoto Matsumura et al.
Garrett N Coyan et al.
Degradable heart valves based on in situ tissue regeneration have been proposed as potentially durable and non-thrombogenic prosthetic alternatives. We evaluated the acute in vivo function, microstructure, mechanics, and thromboresistance o...
Iliocaval Venous Obstruction, Cardiac Preload Reserve and Exercise Limitation [0.03%]
髂下静脉阻塞、心脏前负荷储备和运动限制
Rachael I Morris,Paul A Sobotka,Peter K Balmforth et al.
Rachael I Morris et al.
Cardiac output during exercise increases by as much as fivefold in the untrained man, and by as much as eightfold in the elite athlete. Increasing venous return is a critical but much overlooked component of the physiological response to ex...