Stefan Meier,Michiel Henkens,Stephane Heymans et al.
Stefan Meier et al.
Cardiovascular disease (CVD) is the single greatest cause of mortality and morbidity worldwide. Inciting 85% of CVD fatalities is heart failure, often resulting in or from a myocardial infarction. Early detection along with pharmacological ...
Comparison of High-Dose Rosuvastatin Versus Low-Dose Rosuvastatin Plus Ezetimibe on Carotid Atherosclerotic Plaque Inflammation in Patients with Acute Coronary Syndrome [0.03%]
高强度罗苏伐他汀与低强度罗苏伐他汀联合埃斯西美贝对急性冠脉综合征患者颈动脉粥样硬化斑块炎性影响的比较研究
Minyoung Oh,Hyunji Kim,Eon Woo Shin et al.
Minyoung Oh et al.
We compared the effects of ezetimibe/rosuvastatin 10/5 mg versus rosuvastatin 20 mg on carotid atherosclerotic plaque inflammation measured by 18FDG PET/CT. Fifty patients with acute coronary syndrome (ACS) were randomly assigned to the eze...
Randomized Controlled Trial
Journal of cardiovascular translational research. 2020 Dec;13(6):900-907. DOI:10.1007/s12265-020-10009-4 2020
Nana He,Yuelin Zhang,Shun Zhang et al.
Nana He et al.
Cardiovascular diseases (CVDs) are an important cause of death and disease worldwide. Because injured cardiac tissue cannot be repaired itself, it is urgent to develop other alternate therapies. Stem cells can be differentiated into cardiom...
High Plasma Myeloperoxidase Is Associated with Plaque Erosion in Patients with ST-Segment Elevation Myocardial Infarction [0.03%]
高血浆髓过氧化物酶与ST段抬高性心肌梗死患者的斑块侵蚀相关
Yu Tan,Shujun Yang,Runzhen Chen et al.
Yu Tan et al.
We aimed to investigate the association between plasma myeloperoxidase (MPO) and plaque erosion in patients presenting with ST-segment elevation myocardial infarction (STEMI). Two hundred and fifty-two patients with STEMI who underwent opti...
Involvement of p53 in the Responses of Cardiac Muscle Cells to Heat Shock Exposure and Heat Acclimation [0.03%]
热休克和热习服诱导的心肌细胞中p53的活化及其功能分析
Yifan Chen,Tianzheng Yu
Yifan Chen
Intense heat stress induces damage to the heart, whereas mild to moderate heat stress protects the heart against subsequent ischemic injury. The mechanisms underlying the detrimental and beneficial effects of heat stress remain unclear. In ...
Alessandro Zorzi,Alberto Cipriani,Giulia Mattesi et al.
Alessandro Zorzi et al.
Arrhythmogenic right-ventricular cardiomyopathy (ARVC) is a genetically determined heart disease characterized by progressive myocyte death and substitution by fibrofatty tissue. Life-threatening ventricular arrhythmias may occur during the...
Design and Implementation of an Emergency Action Plan for Sudden Cardiac Arrest in Sport [0.03%]
运动中突发心脏骤停的应急行动计划的设计与实施
Henry F Pelto,Jonathan A Drezner
Henry F Pelto
Sudden cardiac arrest (SCA) is the leading cause of exercise-related fatalities in athletes. A comprehensive emergency action plan (EAP) is critical to facilitate a rapid and effective response to a cardiac emergency. SCA should be suspecte...
Deficient Chaperone-Mediated Autophagy Promotes Lipid Accumulation in Macrophage [0.03%]
自噬功能不全促进巨噬细胞脂质积累
Lei Qiao,He-Feng Wang,Lei Xiang et al.
Lei Qiao et al.
Chaperone-mediated autophagy (CMA) serves as a critical upstream regulator of lipophagy and lipid metabolism in hepatocyte. However, the role of CMA in lipid metabolism of macrophage, the typical component of atherosclerotic plaque, remains...
Myocarditis in the Athlete: Arrhythmogenic Substrates, Clinical Manifestations, Management, and Eligibility Decisions [0.03%]
运动员心肌炎的心律失常 substrate、临床表现、管理及参赛资格决定
Riccardo Vio,Alessandro Zorzi,Domenico Corrado
Riccardo Vio
Myocarditis is as an important cause of sudden cardiac death (SCD) among athletes. The incidence of SCD ascribed to myocarditis did not change after the introduction of pre-participation screening in Italy, due to the transient nature of th...
The Effect of Dobutamine Stress Testing on Vortex Formation Time in Patients Evaluated for Ischemia [0.03%]
多巴胺负荷试验对评估心肌缺血患者旋涡形成时间的影响
Yannis Dimitroglou,Constantina Aggeli,Konstantinos Rapis et al.
Yannis Dimitroglou et al.
Vortex formation time (VFT) is a dimensionless index used to quantify duration of vortex ring formation during diastole. We sought to investigate the effect of pharmaceutical stress on VFT in patients evaluated for ischemia. For this purpos...