Radiomics of Pericoronary Adipose Tissue and CT-FFR to Predict Major Adverse Cardiovascular Events in Patients with T2DM Complicated by CAD [0.03%]
糖尿病冠心病患者冠状动脉周围脂肪组织的影像组学和CT-FFR对不良心血管事件的预测价值研究
Bingcheng Huai,Dixiao Yao,Yi Wang et al.
Bingcheng Huai et al.
This study aims to integrate lesion-specific pericoronary adipose tissue (PCAT) radiomics analysis with existing clinical and imaging methods under the guidance of CT-derived fractional flow reserve (CT-FFR), to develop and validate an inte...
Three-Dimensional Printing in Cardiovascular Medicine: Clinical Applications and Technological Advancements [0.03%]
心血管医学中的三维打印：临床应用与技术革新
Sankara Narayanan Ravi
Sankara Narayanan Ravi
Three-dimensional (3D) printing has rapidly evolved as a transformative technology in cardiovascular medicine, offering capabilities for anatomical modelling, surgical planning, and the development of biocompatible implants. This review syn...
In Vitro Assessment of Coronary Perfusion after Valve-in-Valve Transcatheter Aortic Valve Implantation in a High-Risk Patient-Specific Experimental Model [0.03%]
一种高风险患者的特定实验模型的经导管主动脉瓣植入术后的冠状动脉灌注的体外评估
Francesca Perico,Claudia Romagnoni,Fabio Pappalardo et al.
Francesca Perico et al.
Coronary obstruction following transcatheter aortic valve-in-valve implantation (VIV-TAVI) carries a high mortality risk. This in-vitro study assessed coronary perfusion in a high-risk VIV-TAVI scenario. A patient deemed at high-risk and tr...
The Role of Testosterone in Atherosclerosis: View From Cell Cultures and Animal Models [0.03%]
雄激素在动脉粥样硬化发生发展中的作用：从细胞和动物模型角度看
Siarhei A Dabravolski,Mariam Bagheri Ekta,Aleksandra S Utkina et al.
Siarhei A Dabravolski et al.
Testosterone (TES) has complex roles in cardiovascular disease, influencing not only atherosclerosis development in general, but also atherosclerosis-related processes associated with hypertension, cholesterol metabolism, vascular calcifica...
Extension of Atherosclerosis ApoE-/- Mouse-a Model of Chronic Myocardial Ischemia and Evaluation Method [0.03%]
载脂蛋白E基因敲除小鼠动脉粥样硬化模型在慢性心肌缺血中的应用及评价方法的扩展研究
Zhaobo Wang,Peixun Zheng,Qian Lin et al.
Zhaobo Wang et al.
Chronic myocardial ischemia (CMI) is a key pathological condition in coronary artery disease (CAD), yet small animal models for CMI are limited. This study developed and characterized a CMI mouse model using ApoE-/- mice fed a high-fat diet...
Hyperoside Inhibits Doxorubicin-Induced Ferroptosis in Cardiomyocytes via the Nrf2/GPX4 Pathway [0.03%]
hyperoside通过Nrf2 / GPX4途径抑制秋水仙碱诱导的心肌细胞铁死亡
Mingchun Huang,Yanyan Li,Yuyan Li et al.
Mingchun Huang et al.
Hyperoside (Hyp) exhibits notable protective effects by targeting oxidative stress, ferroptosis, and apoptosis. In vivo experiments used a murine model of DOX-induced cardiotoxicity with Hyp co-treatment. Hyp co-administration mitigated dox...
Hemodynamic Study of Plaque Progression and Regression Based on Coronary CTA Imaging using Computational Fluid Dynamics Method: Preliminary Results [0.03%]
基于冠脉CTA影像的计算流体力学方法评价动脉粥样硬化斑块进展与消退的血流动力学研究：初步结果
Shumin Lv,Lin Yang,Jingao Jiang et al.
Shumin Lv et al.
This study evaluated coronary computed tomography angiography (CCTA)-based computational fluid dynamics (CFD) for predicting plaque dynamics in coronary artery disease. We retrospectively analyzed 22 patients (34 lesions) with paired CCTAs ...
Coronary Artery Calcification: Decoding Mechanisms, Innovations, and Translational Strategies from Bench to Bedside [0.03%]
冠状动脉钙化：从机制、创新到转化策略的解读
Shan Ma,Dan Wu,Yanqing Hu et al.
Shan Ma et al.
Coronary artery calcification (CAC), a key atherosclerotic pathology, has shifted from a passive degenerative marker to an actively regulated process involving osteogenic transdifferentiation, inflammation, and cellular diversity. This revi...
Correction: The SGLT2 Inhibitor Canagliflozin Reduces Atherosclerosis by Enhancing Macrophage Autophagy [0.03%]
correction：钠-葡萄糖协同转运蛋白2抑制剂卡格列净通过增强巨噬细胞自噬减少动脉粥样硬化
Hongping Chen,Da Teng,Bowen Xu et al.
Hongping Chen et al.
PFKFB3 Promotes Myofibroblast Differentiation and Cardiac Fibrosis Through its Intra- and Extra- Cellular Roles [0.03%]
PKFB3通过细胞内和细胞外作用促进肌成纤维细胞分化和心脏纤维化
Bing Han,Zhaowei Zhu,Yongxiang Wang et al.
Bing Han et al.
Cardiac fibrosis remains a major clinical challenge with limited therapeutic options, and the role of PFKFB3 in its pathogenesis remains unclear. Single-cell RNA sequencing analysis was applied and the results demonstrated that glycolysis w...