Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases [0.03%]
冠状脂肪组织：心血管疾病的潜在治疗靶点
Wenxi Fang,Saiyang Xie,Wei Deng
Wenxi Fang
With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide. Although the treatment of CVD has become increasingly advanced, there are still a considerable nu...
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography [0.03%]
金磁纳米颗粒富集基因芯片技术在冠心病遗传易感性研究中的应用分析
Hai-Tao Cao,Cong-Ying Deng,Xin-Min Yan et al.
Hai-Tao Cao et al.
It aimed to explore the correlation of Glu504Lys locus mutation of aldehyde dehydrogenase-2 (ALDH2) with coronary heart disease (CHD) based on gold magnetic nanoparticles (GMNPs) chromatography and amplification refractory mutation system-P...
Advances in Metabolic Remodeling and Intervention Strategies in Heart Failure [0.03%]
心力衰竭中的代谢重塑及干预策略进展
Simin Meng,Yi Yu,Shuo Yu et al.
Simin Meng et al.
The heart is the most energy-demanding organ throughout the whole body. Perturbations or failure in energy metabolism contributes to heart failure (HF), which represents the advanced stage of various heart diseases. The poor prognosis and h...
Mechano-energetic efficiency in patients with hypertrophic cardiomyopathy with and without sarcomeric mutations [0.03%]
肥厚型心肌病患者（含有人和无人类球蛋白基因突变）的机械能量效率
Felice Borrelli,Raffaella Lombardi,Grazia Canciello et al.
Felice Borrelli et al.
Hypertrophic cardiomyopathy (HCM) is mainly caused by sarcomeric mutations which may affect myocardial mechano-energetic efficiency (MEE). We investigated the effects of sarcomeric mutations on MEE. A non-invasive pressure/volume (P/V) anal...
Total Glucosides of Paeony Ameliorate Myocardial Injury in Chronic Heart Failure Rats by Suppressing PARP-1 [0.03%]
芍药总苷通过抑制PARP-1改善慢性心力衰竭大鼠心肌损伤
Wenjuan Wei,Caiyan Li,Baoyong Zhang et al.
Wenjuan Wei et al.
Total glucosides of paeony (TGP) have a potential protective effect on chronic heart failure (CHF) rats, but the mechanism remains unclear. PARP inhibition prevents the decrease in myocardial contractility. Therefore, we aim to investigate ...
Junmei Lu,Emeli Chatterjee,Junjie Xiao
Junmei Lu
Research Progress on Histone Deacetylases Regulating Programmed Cell Death in Atherosclerosis [0.03%]
组蛋白去乙酰化酶调节动脉粥样硬化程序性细胞死亡的研究进展
Gang Zhou,Yanfang Liu,Hui Wu et al.
Gang Zhou et al.
Histone deacetylases (HDACs) are epigenetic modifying enzyme that is closely related to chromatin structure and gene transcription, and numerous studies have found that HDACs play an important regulatory role in atherosclerosis disease. Apo...
Exploring Cutting-Edge Approaches to Potentiate Mesenchymal Stem Cell and Exosome Therapy for Myocardial Infarction [0.03%]
探究促进间充质干细胞和外泌体治疗心肌梗死的前沿策略
Chendong Peng,Jie Yan,Yu&#x;ang Jiang et al.
Chendong Peng et al.
Cardiovascular diseases (CVDs) continue to be a significant global health concern. Many studies have reported promising outcomes from using MSCs and their secreted exosomes in managing various cardiovascular-related diseases like myocardial...
Danlou Tablet Protects Against Myocardial Infarction Through Promoting eNOS-Dependent Endothelial Protection and Angiogenesis [0.03%]
丹参片通过促进eNOS依赖性内皮保护和血管生成防治心肌梗死
Yujiao Zhu,Yibo Chai,Zhuhua Su et al.
Yujiao Zhu et al.
Myocardial infarction (MI) is one of the leading causes of death worldwide. Danlou tablet (Dan) is an effective traditional Chinese medicine for cardiac protection, although the underlying mechanism was not fully understood. In this study, ...
Comparison and Evaluation of Two Combination Modes of Angiotensin for Establishing Murine Aortic Dissection Models [0.03%]
两种降压药联合构建小鼠主动脉夹层模型方法的比较与评价
Wenhui He,Sanjiu Yu,Haoyang Li et al.
Wenhui He et al.
Aortic dissection (AD) is a potentially fatal cardiovascular emergency caused by separation of different layers of aortic wall. However, because of limited time window available for clinical research, there is an urgent need for an ideal an...