Translational Methods for Wearable Heart Rate Variability Monitoring in Older Adults: Preoperative Risk Stratification and Postoperative Monitoring [0.03%]
用于老年成人穿戴式心率变异性监测的转化方法：术前风险分层和术后监护
Nathaniel Brooke,Kenneth C Roberts,Sloan A Soyster Heinz et al.
Nathaniel Brooke et al.
Low preoperative heart rate variability (HRV) is associated with adverse cardiovascular outcomes and delirium after geriatric surgery, but in-person testing is burdensome and impractical. To evaluate wrist-based wearables for remotely captu...
Neutrophil Extracellular Traps and Complement Pathways: The Missing Links in Acute Rheumatic Fever and Rheumatic Heart Disease Pathogenesis [0.03%]
急性风湿热和风湿性心脏病发病机制中中性粒细胞胞外陷阱及补体途径的缺失环节
Saligrama Ramegowda Kalpana,Rudrapatna Subramanyam Jayshree
Saligrama Ramegowda Kalpana
For decades, the pathogenesis of Acute Rheumatic Fever and Rheumatic Heart Disease has been primarily attributed to autoimmune activation in genetically predisposed children, triggered by molecular mimicry between Group A Streptococcus anti...
PAD-associated Genetic Variants are More Strongly Associated with Surgical Intervention than Premature Onset [0.03%]
与手术干预相比，早发性糖尿病相关的遗传变异与PAD的关联更密切
Jiaqi Hu,Dana Alameddine,He Wang et al.
Jiaqi Hu et al.
This study explored the association between 19 peripheral artery disease (PAD)-associated variants and PAD severity. We classified PAD cases into 4 groups with increasing levels of severity based on age of PAD diagnosis and surgical status....
Correlation Between Serum GDF11 Levels and the Progression of Ischemic Mitral Regurgitation and Long-term Prognosis in Patients with ST-segment Elevation Myocardial Infarction After Percutaneous Coronary Intervention [0.03%]
ST段抬高型心肌梗死患者经皮冠状动脉介入治疗后血清GDF11水平与缺血性二尖瓣反流进展及长期预后的相关性研究
Jiangping Ye,Kewei Zong,Yehong Liu et al.
Jiangping Ye et al.
Ischemic mitral regurgitation (IMR) commonly complicates pPCI in STEMI patients. GDF11, a protective cardiovascular factor, may influence IMR progression and prognosis. Among 310 STEMI patients, 126 with recent normal echocardiography under...
Hanna Wang,Anni Määttä,Seppo Ylä-Herttuala
Hanna Wang
Heart failure is the leading cause of hospitalization globally, burdening healthcare systems and the economy. Heart failure is a multifactorial cardiac syndrome, where the heart fails to maintain sufficient cardiac output to support body fu...
Sustained Mechanical Occlusion of the Superior Vena Cava Safely Reduces Cardiac Filling Pressures in a Preclinical Model of Heart Failure [0.03%]
在心力衰竭的临床前模型中，上腔静脉持续机械性阻塞可安全降低心脏充盈压
Peter S Natov,Lara Reyelt,Shreyas Bhave et al.
Peter S Natov et al.
Device-based therapies may augment decongestion in acute decompensated heart failure. We investigated the efficacy and safety of prolonged mechanical superior vena cava occlusion using the preCARDIA system in a swine model of heart failure....
Computational Predictive Modeling of Surgical Outcomes in Total Anomalous Pulmonary Venous Connection: Assessing the Impact of Pulmonary Venous Confluence Size on Preoperative Planning [0.03%]
计算预测模型在完全异常肺静脉连接手术结局的应用：评估肺静脉汇合处大小对术前规划的影响
Jie Jin,Zhuo Shi,Qiang Gao et al.
Jie Jin et al.
To develop a predictive model for optimal anastomosis sizing in TAPVC surgery, focusing on the role of pulmonary venous confluence (PVC) size. A patient-specific fluid-structure interaction (FSI) model simulated blood flow through various a...
Exosomes Enhance Diagnosis and Therapy of Ischemic Heart Disease: Insights and Advances [0.03%]
外泌体改善缺血性心脏病的诊断和治疗：见解与进展
Meng Li,Junping Zhang,Shichao Lv et al.
Meng Li et al.
Ischemic heart disease is a leading cause of global morbidity and mortality, yet early diagnosis and targeted therapies remain limited. Exosomes, small extracellular vesicles carrying nucleic acids, proteins, and lipids, mediate intercellul...
Single-cell Transcriptomic Profiling Reveals Diagnostic of T Cell-platelet Aggregates in Peripheral Blood for Coronary Vulnerable Plaques [0.03%]
单细胞转录组分析发现T细胞血小板聚集体的诊断价值以鉴别易损斑块患者与非易损斑块患者
Diru Yao,Peina Meng,Bin Huang et al.
Diru Yao et al.
Acute coronary syndrome, driven by vulnerable plaque (VP) instability, is a major cause of cardiovascular mortality. Current diagnostic methods for VPs are limited by invasiveness or low specificity, highlighting the need for non-invasive b...
Pulmonary Artery Banding: an Effective in-vivo Acute Model of Functional Tricuspid Regurgitation for Transcatheter Interventions [0.03%]
肺动脉束带成型术：一种有效的经皮介入治疗三尖瓣反流的在体急性模型
Guido Ascione,Stefano Stella,Alessandro Addis et al.
Guido Ascione et al.
Tricuspid regurgitation (TR) is a highly morbid and often untreated valvular heart disease. New devices are under development to address this unmet need, necessitating valid models to test their efficacy. Aim of this study was to assess fea...