AIM2 Deficiency Alleviates Cardiac Inflammation and Hypertrophy in HFD/STZ-Induced Diabetic Mice by Inhibiting the NLRC4/IRF1 Signaling Pathway [0.03%]
AIM2缺陷通过抑制NLRC4/IRF1信号通路缓解高脂饮食合并链脲佐菌素诱导的糖尿病小鼠心脏炎症和肥大
Jian-Ping Wu,Cheng Wu,Yuan-Ji Ma et al.
Jian-Ping Wu et al.
Absent in melanoma 2(AIM2) exacerbates atherosclerosis by inflammasome assembly. However, AIM2-mediated inflammation in diabetic cardiomyopathy remains incompletely understood. Here we investigate the role of AIM2 in high glucose (HG)- and ...
Adult Cardiomyocyte-Derived Extracellular Vesicles: a Promising Therapy for Cardiac Fibrosis [0.03%]
有希望用于治疗心脏纤维化的成年心肌细胞源外泌体疗法
Hongyun Wang,Xinpeng Li,Qianwen Wu et al.
Hongyun Wang et al.
An Updated Comprehensive Review of Existing Transcatheter Aortic Valve Replacement Access [0.03%]
经导管主动脉瓣置换术入路的全面综述更新
Wenjing Sheng,Hanyi Dai,Rongrong Zheng et al.
Wenjing Sheng et al.
For the past 20 years, transcatheter aortic valve replacement (TAVR) has been the treatment of choice for symptomatic aortic stenosis. The transfemoral (TF) access is considered the gold standard approach for TAVR. However, TF-TAVR cannot b...
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease [0.03%]
心囊内给药以实现心脏疾病的局部化和靶向治疗
Yaping Xu,Yan Chen,Jun Jie Tan et al.
Yaping Xu et al.
Intrapericardial administration has been proposed as an alternative delivery route of pharmacological agents via the bilaminar sac of pericardium surrounding the heart. To date, intrapericardial administration has entailed the localized adm...
Clinical Outcome of Hypertrophic Cardiomyopathy in Probands with the Founder Variant c.913_914del in MYBPC3: A Slovenian Cohort Study [0.03%]
SLAV族系c.913_914del(MYBPC3基因变异)所致肥厚型心肌病患者的临床转归：斯洛文尼亚队列研究
Nina Vodnjov,Aleš Maver,Nataša Teran et al.
Nina Vodnjov et al.
Hypertrophic cardiomyopathy is often caused by pathogenic MYBPC3 variants. The study of Italian patients with HCM and MYBPC3(NM_000256.3):c.913_914del showed a higher disease penetrance in males and a higher frequency of arrhythmias compare...
Daisy Guamán-Pilco,Elvira Chocano,Elena Palà et al.
Daisy Guamán-Pilco et al.
The study investigates the utility of heart fatty-acid binding protein (H-FABP) in distinguishing TIA from mimics. Data from 175 patients from the StrokeChip multicenter study was retrospectively analyzed. H-FABP level was measured using a ...
A Kernel Attention-based Transformer Model for Survival Prediction of Heart Disease Patients [0.03%]
一种基于核心关注的变压器模型的心脏病患者生存预测方法
Palak Kaushal,Shailendra Singh,Rajesh Vijayvergiya
Palak Kaushal
Survival analysis is employed to scrutinize time-to-event data, with emphasis on comprehending the duration until the occurrence of a specific event. In this article, we introduce two novel survival prediction models: CosAttnSurv and CosAtt...
Force Analysis Using Self-Expandable Valve Fluoroscopic Imaging: a way Through Artificial Intelligence [0.03%]
基于自膨胀瓣膜造影的力分析：通过人工智能实现的一种方法
Yiming Qi,Xiaochun Zhang,Zhiyun Shen et al.
Yiming Qi et al.
This study aimed to develop a force analysis model correlating fluoroscopic images of self-expandable valves with stress distribution. For this purpose, a nonmetallic measuring device designed to apply diverse forces at specific positions o...
Wei Chen,Meiyu Hu,Juan Gao et al.
Wei Chen et al.
Yushu Xie,Jie Xie,Liang Li
Yushu Xie
Methylation modification is a crucial epigenetic alteration encompassing RNA methylation, DNA methylation, and histone methylation. Ferroptosis represents a newly discovered form of programmed cell death (PCD) in 2012, which is characterize...