Circulating Extracellular Vesicles from Heart Failure Patients Inhibit Human Cardiomyocyte Activities [0.03%]
心力衰竭患者循环中的细胞外囊泡可抑制人类心脏成纤维细胞的活性
Ke Zhen,Xiaojuan Wei,Zelun Zhi et al.
Ke Zhen et al.
Extracellular vesicles (EVs) have been implicated in cardiac remodeling during heart failure (HF). However, the role of circulating EVs (CEVs) in the process of HF is poorly understood. To elucidate the molecular mechanism associated with C...
Induction of Controllable Vortical Flow in a Dual-Stenosis Aorta Model: A Replication of Disordered Eddies Flow in Aneurysms [0.03%]
主动脉双狭窄模型中可控涡流的诱发：动脉瘤内紊乱涡流的一种复制现象
Zhijie Wang,Zonghan Lyu,Jingfeng Jiang
Zhijie Wang
This paper presents a two-stenosis aorta model mimicking vortical flow in vascular aneurysms. More specifically, we propose to virtually induce two adjacent stenoses in the abdominal aorta to develop various vortical flow zones post stenose...
4D-Flow MRI and Vector Ultrasound in the In-Vitro Evaluation of Surgical Aortic Heart Valves - a Pilot Study [0.03%]
基于4D流磁共振和向量超声的主动脉瓣置换术离体评价研究——一项前瞻性研究
Henrik Stephan,Linda Grefen,Dirk Clevert et al.
Henrik Stephan et al.
Introduction: The aim of this study was the initial investigation of 4D-Flow MRI and Vector Ultrasound as novel imaging techniques in the in-vitro analysis of hemodynamics in anatomical models. Specifically, by looking at...
Past Trends and Future Directions of Cardiac Regenerative Medicine - A Systematic Analysis of Clinical Trial Registries [0.03%]
心脏再生医学的过去趋势和未来方向——临床试验注册表的系统分析
Maaike Wulfse,Mats T Vervoorn,Jantijn J G J Amelink et al.
Maaike Wulfse et al.
Cell therapy, gene therapy, and tissue engineering have been explored as potential strategies to repair or regenerate damaged cardiac tissue. Despite the presence of encouraging preclinical data, clinical trials of regenerative cardiac ther...
Moizle Grace Castro Ocariza,Louise Nancy Paton,Evelyn Mary Templeton et al.
Moizle Grace Castro Ocariza et al.
The heart requires a substantial amount of energy to function, utilising various substrates including lipids, glucose and lactate as energy sources. In times of increased stress, lactate becomes the primary energy source of the heart, but p...
Hemodynamic Analysis in Aortic Dilatation after Arterial Switch Operation for Patients with Transposition of Great Arteries Using Computational Fluid Dynamics [0.03%]
计算流体力学在大动脉转位Switch手术后主动脉扩张中的血动力学分析
Woo Young Park,Sang Yun Lee,Jongmin Seo
Woo Young Park
After an arterial switch operation for complete transposition of the great arteries, neo-aortic root dilatation occurs, with unclear hemodynamic effects. This study analyzes three groups (severe dilation, mild dilation, and normal) using co...
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) - A Prospective, Multicentre Cohort Study [0.03%]
轻链细胞外囊泡预测射血分数轻度降低的心力衰竭患者舒张功能障碍的进展（LYCHEE研究）：一项前瞻性多中心队列研究
Aleksandra Gąsecka,Aleksander Siniarski,Piotr Duchnowski et al.
Aleksandra Gąsecka et al.
Risk stratification in heart failure with mildly-reduced ejection fraction (HFmrEF) remains challenging. We evaluated the predictive value of advanced glycation end products (AGEs) and plasma concentrations of extracellular vesicles (EVs) f...
Dysfunctional HDL Diagnostic Metrics for Cardiovascular Disease Risk Stratification: Are we Ready to Implement in Clinics? [0.03%]
心血管疾病风险分层的异常HDL诊断指标：我们准备好在诊所实施了吗？
Swetha N Kempegowda,Kavya Sugur,Rajesh K Thimmulappa
Swetha N Kempegowda
Epidemiological studies have revealed that patients with higher levels of high-density lipoprotein cholesterol (HDL-C) were more resistant to cardiovascular diseases (CVD), and yet targeting HDL for CVD prevention, risk assessment, and phar...
Assessment of CMR Feature-Tracking Age- and Sex-Dependent Right Ventricular Strain in a Healthy Caucasian Cohort [0.03%]
欧洲裔健康人群中右心室应变的年龄和性别依赖性CMR特征追踪评估
Jan Eckstein,Hermann Körperich,Oliver M Weber et al.
Jan Eckstein et al.
Right ventricular (RV) strain offers crucial diagnostic insights in cardiovascular and pulmonary disorders. Nonetheless, the absence of established reference values impedes its clinical implementation. Utilizing CMR-feature tracking, age- a...
Pearls and Pitfalls of Epicardial Echocardiography for Implantation of Impella CP Devices in Ovine Models [0.03%]
绵羊模型中植入Impella CP装置的超声心动图经胸检查的要点及陷阱
Konstantin Yastrebov,Laurencie M Brunel,Fiona C Schnitzler et al.
Konstantin Yastrebov et al.
The Impella CP is a percutaneously inserted temporary left ventricular assist device used in clinical practice and in translational research into cardiogenic shock, perioperative cardiac surgery, acute cardiac failure and mechanical circula...