Endothelial Cell-Derived Extracellular Vesicles Allow to Differentiate Between Various Endotypes of INOCA: A Multicentre, Prospective, Cohort Study [0.03%]
内皮细胞来源的外泌体用于区分INOCA的各种表型：一项多中心前瞻性队列研究
Aleksandra Gąsecka,Piotr Szolc,Edwin van der Pol et al.
Aleksandra Gąsecka et al.
Ischemia and non-obstructive coronary artery disease (INOCA) might be due to coronary microvascular dysfunction (CMD), vasospastic angina (VSA) or both. We compared plasma concentration of various extracellular vesicles (EVs) in patients wi...
Hyperspectral Imaging for Microcirculatory Assessment of Patients undergoing Transcatheter and Surgical Aortic Valve Replacement-a Prospective Observational Pilot Study [0.03%]
基于导管和外科主动脉瓣膜置换患者的微循环 hyperspectral 影像评估：前瞻性观察研究
Maximilian Dietrich,Aycan Tayan,Tobias Hölle et al.
Maximilian Dietrich et al.
This prospective, observational study evaluated Hyperspectral Imaging (HSI) to assess the effects of cardiac surgery and cardiopulmonary bypass (CPB) on microcirculation. 40 Patients with severe aortic stenosis were enrolled. 20 patients un...
β-Hydroxybutyrate and Citrate Synthase as Potential Diagnostic Biomarkers in Aging-Related Atrial Fibrillation [0.03%]
β-羟丁酸和柠檬酸合酶作为与衰老相关房颤的潜在诊断生物标志物
Jia-Kang He,Xiao-Xiao Jiang,Shi-Yu Dai et al.
Jia-Kang He et al.
The incidence of atrial fibrillation (AF) increases with age; however, the precise mechanisms by which aging elevates AF risk and the effective biomarkers for managing AF in elderly patients remain unclear. We analyzed plasma samples from 1...
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction [0.03%]
一种新型双层真空压制生物支架补片的机械和几何特性在后瓣膜二尖瓣重建中的应用研究
Johannes H Jedrzejczyk,Frederik T Andersen,Jacob Petersen et al.
Johannes H Jedrzejczyk et al.
To assess the mechanical properties of small intestinal submucosal extracellular matrix (SIS-ECM) iterations and choose the optimal version for evaluating functional geometrics after posterior mitral valve reconstruction. Four SIS-ECM versi...
Shorter Leukocyte Telomere Length Is Associated with Increased Major Adverse Cardiovascular Events or Mortality in Patients with Essential Hypertension [0.03%]
原发性高血压患者端粒缩短与主要不良心血管事件或死亡率增加有关
Hongna Fu,Yuanting Zhu,Luyang Lin et al.
Hongna Fu et al.
The association between leukocyte telomere length (LTL) alteration and major adverse cardiovascular events (MACE) or mortality in patients with hypertension is still unclear. 20,034 patients with essential hypertension were enrolled from UK...
Adaptation of Aortic Bioprosthetic Valves for Pulmonary Position: Comparative Analysis of Transcatheter and Surgical Valves [0.03%]
经导管和外科主动脉生物瓣膜用于肺动脉位置的适应性分析：对比研究
Mina Shafiei,Dong Qiu,Ali N Azadani
Mina Shafiei
Pulmonary valve dysfunction is common in congenital heart disease, often leading to interventions like right ventricular outflow tract reconstruction. Transcatheter pulmonary valve replacement (TPVR) has emerged as a successful alternative ...
Apolipoprotein A-I Mimetic Peptide Restores VEGF-induced Angiogenesis in Hypercholesterolemic Ischemic Heart by Reducing HDL Proinflammatory Properties [0.03%]
apoA-I模拟剂通过降低HDL促炎特性恢复高胆固醇缺血心脏病中VEGF诱导的血管生成作用
Zui Liu,Yang Cao,Xiao-Long Liao et al.
Zui Liu et al.
VEGF-induced angiogenesis is impaired in hypercholesterolemia. Previous studies showed that an apolipoprotein A-I(ApoA-I) mimetic peptide, D-4F, is able to reduce HDL proinflammatory index in hypercholesterolemia. Whether D-4F promotes angi...
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive? [0.03%]
在致心律失常性心肌病中通过GSK-3β靶向 canonical Wnt信号通路：保守还是进步？
Brandon Shu Huang Low,Angeliki Asimaki
Brandon Shu Huang Low
Arrhythmogenic cardiomyopathy is a primary myocardial disease and a major cause of sudden death in all populations of the world. Canonical Wnt signalling is a critical pathway controlling numerous processes including cellular differentiatio...
Drp1 Promotes Macrophage M1 Polarization and Inflammatory Response in Autoimmune Myocarditis by Driving Mitochondrial Fission [0.03%]
DRP1通过促进线粒体分裂驱动自身免疫性心肌炎巨噬细胞M1极化和炎症反应
Lin Lin,Jin Wei,Jiahong Xue et al.
Lin Lin et al.
Autoimmune myocarditis (AM) is characterized by an intricate inflammatory response within the myocardium. Dynamin-related protein 1 (Drp1), a pivotal modulator of mitochondrial fission, plays a role in the pathogenesis of various diseases. ...
Machine Learning Model for Predicting Risk Factors of Prolonged Length of Hospital Stay in Patients with Aortic Dissection: a Retrospective Clinical Study [0.03%]
主动脉夹层患者住院时间延长的危险因素预测模型构建及验证——一项回顾性临床研究
Luo Li,Yihuan Chen,Hui Xie et al.
Luo Li et al.
The length of hospital stay (LOS) is crucial for assessing medical service quality. This study aimed to develop machine learning models for predicting risk factors of prolonged LOS in patients with aortic dissection (AD). The data of 516 AD...